Perioral Dermatitis Slide

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Presented By:

1. 2. 3.

Ira Ulil Inayah Wahid C 111 07 239 Christya Lorena G C 111 07 263 Siti Alis Solihan bt Ramli C 111 07 295 Advisor: dr. Hartati Supervisor: dr. Dirmawati Kadir, Sp. KK
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Introduction:
Perioral dermatitis (PD) is an eruption of

papules or small papulopustules around the


mouth. Usually as a respond to topical

corticosteroid or cosmetics used.


Its manifests as scaling, papules or

papulopustules with erithematous


background.
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Epidemiology
Perioral dermatitis (PD) is most commonly

found in young women at their age of 15-40 years old with peak incidens at 25-35 years old.
In children girls and boys are in the same risk

to develop PD
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Etiology:
Medications: misused of topical

corticosteroid
Cosmetics: toothpaste (due to the contain

of flouride), lotion and cream which

contain paraffin and isopropyl myristate

Etiology:
Physical factors: UV light, hot and

polluted air
Microbiology factors: Fusiform spirillia,

Candidia, and Demodex folliculorum


Other factors: hormonal factors, oral

contraception, malabsorptions
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Pathogenesis
The exact pathogenesis of PD is

unknown.
But it is assumed that edema and

vasodilatation of papillary dermis,


perivascular and also infiltration of

lymphocyte, histiocyte and PMN in


parafollicular
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Diagnosis
Anamnesis:

1. Usually the lesion


appears for weeks to months 2. Itchy usually absent

3. Burning sensation usually absent

Diagnosis
Lesion characteristics:

1. Erythematous papulopustules on an
erythematous background, symmetry, grouped

as satellite .
2. Confluent plaques may appear eczematous with tiny scales. There are no comedones.
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Diagnosis:
Predillections:

Initially perioral. Rim of sparing around the vermilion border of lips.

Differential diagnosis
1. Allergy Contact dermatitis

2. Atopic dermatitis
3. Seborrhoic dermatitis 4. Rosasea 5. Acne vulgaris 6. Dermatitis liplicker
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Dermatitis perioral

Dermatitis perioral

Allergy contact dermatitis

Atopic dermatitis

Seborrhoic dermatitis

Rosasea

Acne vulgaris

Dermatitis liplicker

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Management:
1. Nonmedication:
- Identify the causative agent (cosmetic or

topical corticosteroid etc) and stop the

usage. Beware of rebound phenomenon for


corticosteroid usage.

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Management:
2. Medication: - Topical antibiotic most commonly use is Metronidazole - Systemic antibiotic most commonly used is Tetracyclin - Calcineurine inhibitor topical - Photodinamic therapy (5-aminolevulinic topical)
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TOPIKAL

DOSIS

SISTEMIK

DOSIS

First line

Metronidazol

2x1

Tetrasiklin Doksisiklin Minosiklin

250-500 mg 2x1/hr 50-100 mg 2x1/hr 50-100 mg 2x1/hr

Second line

Eritromisin atau Klindamisin Sulfur Asam azelaic

2x1 2x1 2x1 2x1

Eritromisin

400 mg 3x1/hr atau 30-50 mg/kgBB/hr

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Complication:
Psychological and can cause lack of self

confidence
Rebound phenomena due to stoppage of

corticosteroid

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Prognosis:
Cureable with broad spectrum antibiotics
Relapse to some patients If not immediately treated or if topical

corticosteroid is continously used this PD


can progress to years
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Conclusion:
PD is eruption of Perioral dermatitis is an

eruption of papules or small papulopustules


around the mouth. Usually as a respond to topical corticosteroid or cosmetics used.
Its manifests as scaling, papules or

papulopustules with eritematous background.


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Conclusion:
Perioral dermatitis (PD) is most commonly

found in young women at their age of 15-40 years old with peak incidens at 25-35 years old. To manage PD, stop the usage of causative agent. Give topical antibiotic (Metronidazole), systemic antibiotic most commonly used is Tetracyclin
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Thank You

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