46 Tic Disorders
46 Tic Disorders
46 Tic Disorders
Betita, Durell S.
Oliveros, Vanessa D.
TICS
defined as rapid and repetitive muscle
contractions resulting in movements or
vocalizations that are experienced as
involuntary
abnormal movements or vocalizations that most
commonly affect the muscles of the face & neck
eye-blinking, head-jerking, mouth-grimacing, head-shaking
Vocal Tics: throat-clearing, grunting, snorting, and
coughing
Ordering
Symmetry
Counting
Repetitive Touching
MOTOR TICS
Simple Motor Tics repetitive, rapid contractions
of functionally similar muscle groups (eye-blinking,
neck-jerking, shoulder shrugging, facial-grimacing)
Complex Motor Tics purposeful, ritualistic than
simple tics (grooming behaviors, smelling of
objects, jumping, touching behaviors, echopraxia
or imitation of observed behavior, copropraxia or
display of obscene gestures
VOCAL TICS
Simple Vocal Tics coughing, throatclearing, grunting, sniffing, snorting, barking
Complex Vocal Tics repeating of words
or phrases out of context, coprolalia or use
of obscene words or phrases, palilalia or
repeating own words, echolalia or repetition
of last-heard words of others
Tourettes Disorder
Multiple Motor & one or more Vocal Tics
EPIDEMIOLOGY
4-5 per 10,000
More in children than adults
Onset of motor component occurs at 7
years old; vocal tics emerge at 11 years
old
More often in boys than girls
ETIOLOGY
Genetic Factors more in monozygotic twins than
dizogytic, transmission in autosomal dominant fashion,
relation to ADHD (half of all Tourettes patients)
Neurochemical & Neuroanatomical Factors dopamine
system involvement
Immunological Factors & Postinfection autoimmune
process secondary to Streptococcal infections as
potential mechanism , also associated in OCD
development
DIFFERENTIALS
Disordered Movements
(Dystonic, Choreiform, Athetoid,
Myoclonic, Hemiballismic)
Tremors, mannerisms,
stereotypic movement disorder
(head-banging, body rocking)
EPIDEMIOLOGY
100 1,000 X greater than Tourettes
School boys at higest risk, unknown
incidence
Rare, 1-2% of population
ETIOLOGY
High concordance in
monozygotic twins
DIFFERENTIAL
DIAGNOSIS
Motor movements
Involuntary Vocal Utterances
(Huntingtons, Parkinsons)
TREATMENT
Psychotherapy
Reversal Treatments
Anxiolytic Agents