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    The Reactions of Bioconjugation

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    Alberto Carlos Espinosa Garavito
    The document discusses various reactions that can be used for bioconjugation with thiols, including reactions with haloacetyl and alkyl halide derivatives, maleimides, aziridines, acryloyl derivatives, arylating agents, thiol-disulfide exchange reagents like pyridyl disulfides and TNB-thiol, disulfide reductants, vinyl sulfone derivatives, metal-thiol dative bonds, native chemical ligation, and cisplatin modification of methionine and cysteine residues.

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    The Reactions of Bioconjugation

    Uploaded by

    Alberto Carlos Espinosa Garavito
    24 views15 pages
    The document discusses various reactions that can be used for bioconjugation with thiols, including reactions with haloacetyl and alkyl halide derivatives, maleimides, aziridines, acryloyl derivatives, arylating agents, thiol-disulfide exchange reagents like pyridyl disulfides and TNB-thiol, disulfide reductants, vinyl sulfone derivatives, metal-thiol dative bonds, native chemical ligation, and cisplatin modification of methionine and cysteine residues.

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    THE REACTIONS OF BIOCONJUGATION.pptx

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    The document discusses various reactions that can be used for bioconjugation with thiols, including reactions with haloacetyl and alkyl halide derivatives, maleimides, aziridines, acryloyl derivatives, arylating agents, thiol-disulfide exchange reagents like pyridyl disulfides and TNB-thiol, disulfide reductants, vinyl sulfone derivatives, metal-thiol dative bonds, native chemical ligation, and cisplatin modification of methionine and cysteine residues.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    24 views15 pages

    The Reactions of Bioconjugation

    Uploaded by

    Alberto Carlos Espinosa Garavito
    The document discusses various reactions that can be used for bioconjugation with thiols, including reactions with haloacetyl and alkyl halide derivatives, maleimides, aziridines, acryloyl derivatives, arylating agents, thiol-disulfide exchange reagents like pyridyl disulfides and TNB-thiol, disulfide reductants, vinyl sulfone derivatives, metal-thiol dative bonds, native chemical ligation, and cisplatin modification of methionine and cysteine residues.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 15

    THE REACTIONS OF

    BIOCONJUGATION
    THIOLS REACTION
    THIOLS REACTION
    2.1 Haloacetyl and Alkyl Halide Derivatives
    THIOLS REACTION
    2.2. Maleimides
    THIOLS REACTION
    2.3. Aziridines
    THIOLS REACTION
    2.4. Acryloyl Derivatives
    THIOLS REACTION
    2.5. Arylating Agents
    THIOLS REACTION
    2.6. Thiol–Disulfide Exchange Reagents
    THIOLS REACTION
    Pyridyl Disulfides
    THIOLS REACTION
    TNB-Thiol
    THIOLS REACTION
    Disulfide Reductants
    THIOLS REACTION
    2.7. Vinyl Sulfone Derivatives
    THIOLS REACTION
    2.8. Metal–Thiol Dative Bonds
    THIOLS REACTION
    2.8. Metal–Thiol Dative Bonds
    THIOLS REACTION
    2.9. Native Chemical Ligation
    THIOLS REACTION
    2.10. Cisplatin Modification of Methionine and Cysteine

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