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Algorithms: Chou Fasman

The document discusses the Chou-Fasman parameters used for predicting secondary protein structure. It provides a table that lists the amino acids and their probabilities (P) of forming an alpha helix, beta sheet, or turn. It also lists factors (f) that influence the formation of each secondary structure based on neighboring residues. A typical protein contains 32% alpha helix, 21% beta sheets and 47% loops.

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Patel Bansari
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45 views

Algorithms: Chou Fasman

The document discusses the Chou-Fasman parameters used for predicting secondary protein structure. It provides a table that lists the amino acids and their probabilities (P) of forming an alpha helix, beta sheet, or turn. It also lists factors (f) that influence the formation of each secondary structure based on neighboring residues. A typical protein contains 32% alpha helix, 21% beta sheets and 47% loops.

Uploaded by

Patel Bansari
Copyright
© © All Rights Reserved
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd
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algorithms

Chou fasman
A typical protein contains 32% α –helix, 21% β
sheets and 47% loops
Chou-Fasman Parameters
Name Abbrv P(a) P(b) P(turn) f(i) f(i+1) f(i+2) f(i+3)
Alanine A 142 83 66 0.06 0.076 0.035 0.058
Arginine R 98 93 95 0.07 0.106 0.099 0.085
Aspartic Acid D 101 54 146 0.147 0.11 0.179 0.081
Asparagine N 67 89 156 0.161 0.083 0.191 0.091
Cysteine C 70 119 119 0.149 0.05 0.117 0.128
Glutamic Acid E 151 37 74 0.056 0.06 0.077 0.064
Glutamine Q 111 110 98 0.074 0.098 0.037 0.098
Glycine G 57 75 156 0.102 0.085 0.19 0.152
Histidine H 100 87 95 0.14 0.047 0.093 0.054
Isoleucine I 108 160 47 0.043 0.034 0.013 0.056
Leucine L 121 130 59 0.061 0.025 0.036 0.07
Lysine K 114 74 101 0.055 0.115 0.072 0.095
Methionine M 145 105 60 0.068 0.082 0.014 0.055
Phenylalanine F 113 138 60 0.059 0.041 0.065 0.065
Proline P 57 55 152 0.102 0.301 0.034 0.068
Serine S 77 75 143 0.12 0.139 0.125 0.106
Threonine T 83 119 96 0.086 0.108 0.065 0.079
Tryptophan W 108 137 96 0.077 0.013 0.064 0.167
Tyrosine Y 69 147 114 0.082 0.065 0.114 0.125
Valine V 106 170 50 0.062 0.048 0.028 0.053

Protein Folding 12

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