Disorders of Epiphyses and Epiphyseal Growth - IGN

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Disorders of

Epiphyses and
Epiphyseal Growth
Disorders of Epiphysis and
Epiphyseal Plates:
• Generalized
• Congenital (ex. Achondroplasia)
• Acquired (ex. Rickets)
• Localized
• Pressure type (Leg-Calve-Perthes Disease)
• Traction type (ex. Tibial tubercle / Osgood-
Schlatter Disease)
• Osteochondrosis: an idiopathic type of
avascular necrosis.
Nutrition of The Epiphysis and
Its Epiphyseal Plate
• Most pressure epiphysis are
covered essentially by articular
cartilage and receive blood
vessels only from their bare
bone area.
• Femoral head, being completely
intraarticular, and completely
covered by articular cartilage so
the blood supply precariously
must penetrate the cartilage
clothing.
• Disruption of ephypiseal blood
vessels leads to ischemia of
epiphyseal plate and growth
disturbance.
Avascular Necrosis of Bone
• Series of pathological events from the
initial loss of blood supply and resultant
death of bone to the gradual replacement
of the dead bone by living bone.
• Etiology:
• Genetically determined vascular configuration.
• Trauma
• Tense synovial effusion.
Idiopathic Avascular Necrosis of
Epiphyses (Osteochondroses)
• Synonims: Epiphysitis, Osteochondrosis,
Aseptic Necrosis, Ischemic Epiphyseal
Necrosis  confusing.
• Kohler Disease, Osgood Schlatter Disease,
Leg-Calve-Perthes Disease  more
confusing.
• The etiology is similar in every entities.
General Feature of
Osteochondroses
• Incident and Etiology
• Most common: 3-10 years old
• Boys > girls
• Lower limbs > upper limbs
• Pathogenesis and Pathology
• Osteochondroses is a self-limiting disease, with or
without treatment.
• Phases:
• Early Phase of Necrosis
• Phase of Revascularization with Bone Deposition and
Resorption
• Phase of Bone Healing
• Phase of Residual Deformity
Clinical Feature and Diagnosis
• Quiet-early phase of necroses, osteochondroses produce
neither symptomps nor clinical signs.
• Revascularization phase, if a pathological fracture develops in
the subchondral bone, the pain will appear.
• Synovial effusion develops causing local tenderness and
painful limitation of motion in the joint, especially in
abduction.
• If left untreated, symtomps and sign will be intermitten,
causing disuse atrophy of involved muscle.
• Differential diagnosis:
• Irregular ossification in normal epiphysis.
• Generalized disorders suc as hypothyroidism and epiphyseal
dysplasia.
Sequelae
• Subchondral fracture in the epiphysis
• Subluxation of the involved joint
• Deformity of epiphysis with resultant joint
incongruity
• Secondary degenerative joint disease.
Aim and Principles of Treatment
• The aims of treatments:
• Prevent the epiphyseal deformity.
• Preserve the congruity of joint to prevent secondary
osteoarthritis.
• The principles of treatment:
• Prevention of abnormal forces on the epiphysis during
the vulnerable phase of revascularization and healing.

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