Presentation On Walnut

Presentation by
WALNUT ( Juglans Regia) In

Rheumatoid Arthritis
Research To be Carried on
Kasmiri origin WALNUT ( JUGLANS Regia)
At
Dr Naseer’s Unani and Panchkarma Hospital
Presentation By/
Dr. Majid-Ul-Majid
Sr. Unani Physician
Unani & Panchkarma Hospital
Brief Resume of The Intended Work
Introduction & Need of Study
Walnuts are among the most widely consumed commercially grown tree nuts in the world. Many health benefits
have been claimed for the consumption of these, including reduced risk of cardiovascular disease, coronary
heart disease, type II diabetes treatment, and prevention and treatment of certain cancers, and the lessening of
symptoms attributed to age-related and other neurological disorders. The polyphenols in walnuts can help fight
this oxidative stress and inflammation. A subgroup of polyphenols called ellagitannins may be especially
involved.
STUDY ON RHUMATOID ARTHRITIS: Rheumatoid arthritis (RA) is an autoimmune disease that

can cause joint pain and damage throughout your body. RA is an autoimmune disease, which
means the arthritis results from your immune system attacking your body's own tissues.
• NO CURE OF RHUMATOID ARTHRITIS : Although there's no cure for rheumatoid arthritis, early treatment
and support (including lifestyle changes, medication, supportive treatments and surgery) can reduce the
risk of joint damage and limit the impact of the condition. The disease-modifying anti rheumatic drugs
(DMARDs) are laden with severe side effects on the body as a whole. So a need arises to explore
scientifically some of the safe and effective naturally available foods/drugs and Walnut is one such
product which has the potential to manage the Rheumatoid Arthritis.
Walnut in Rheumatoid Arthritis: The pharmacological research showed that walnut kernel could clear away
the free radical, inhibit the lipid peroxidation damage. Due to presence of high density lipoproteins (HDL)
but we are observing tremendous scope of walnut in RHUMATIOD ARTHRITIS. the aqueous (2.87 and 1.64
g/kg) and ethanol (2.044 and 1.17 g/kg) Extract of fruit showed antinociceptive activity in hotplate test
suggesting a promising analgesic and anti-inflammatory agents against diseases such as rheumatoid arthritis.
Objective of study
• Scientifically validate the adjuvant effect of walnut in the management of rheumatoid arthritis .
• To develop effective , safe and low-cosat drug for rheumatoid arthritis
• To give an marketing boost to the local walnut industry by validating its medicinal effects besides walnut
being a known dry fruit.
Material and Methods

Source of data
• Data will be generated from the clinical studies at The Unani And Panchkarma Hospitals, Srinagar, J&k
Method of collection of Data / Plant material
• walnut(Juglans Regia) will be procured from the authentic source. The identity of the drug will be confirmed by the
pharmacognosist/ botanist.
Test drug (dose and route of administration)
• Dry ripe walnuts will be given in the dosage of 2 nuts (kernel weight average 28gm/nut) thrice a day with a gap of 6 hrs.
• Duration of the treatment = 45 days
Patient Screening:
Patient will be selected in random methods visiting Unani and panchkarma Hospital after fulfilling the basic criteria to be
declared as case of Rheumatoid Arthritis.
Inclusive Criteria
• Age Below 70 years
• Sex: Either Sex
Exclusive Criteria
Patients with Gouty Arthritis, Osteoarthritis, Psoriatic arthritis, Ankylosing arthritis shall be
Excluded in the study
Investigations to be carried out
• International Criteria for Rheumatoid Arthritis will be followed ( DAS & EULAR CRITERIA)
• RA,CRP,ESR,CBC,ANTICCP Shall be observed apart from important clinical features.
• Investigation and assessment of the disease course will be done at an interval of 15 days both
in the Test Group and Control Group
0th Day 15th Day 30th Day 45th Day Respectively
Patient Consent
• Full consent of the patient/ guardian will be taken after explaining the pros and cones of the
said study in the local language of the patient.
Written consent
• Written consent will be taken from the patient/ guardian on the standard case registration
form(CRF).
Test Drug
• Test drug (walnut) will be provided free to the patient as per the research protocol and will
be used as adjuvant drug to conduct the research.
Controlled Drug
• Test drug (walnut) will be provided free to the patient as per the research protocol.
Ethical clearance
• The study will be carried after proper ethical clearance from the concerned authorities.
Thank you
For your valuable time
Dr.Majid-Ul-Majid
Sr. Unani Physician
Unani and panchkarma Hospital

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Presentation On Walnut

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Presentation by

WALNUT ( Juglans Regia) In

STUDY ON RHUMATOID ARTHRITIS: Rheumatoid arthritis (RA) is an autoimmune disease that

Material and Methods

For your valuable time

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