Case Presentation: Pediatrics Rotation

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CASE PRESENTATION

Pediatrics Rotation
By Stephanie Piotrovsky, PA-S
The Case Presentation
• A seven year old male comes to the
clinic with multiple crusted lesions
around the mouth, nose, and on the
trunk.
• The patient has no other complaints.
• Vital signs are within normal limits.
• No fever at this time.
• No past surgical, medical history
• Immunizations up to date
DIFFERENTIAL
DIAGNOSIS
• IMPETIGO
– Bullous Vs. Nonbullous
• ECTHYMA
• HSV-1
• VARICELLA
• DERMATITIS
• TINEA CAPITUS
The History (HPI)
(Elicited from mother and child)
 How long have the lesions been present?
 Approximately, one week
 Has their appearance changed?
 Mom states that it started out as small pink
bumps around his nose and mouth one week
ago. A few days later, he had blisters in the
same areas and also on his chest and right
arm. Two days ago, she noticed the crusting
and it hasn’t changed since.
 Do the lesions itch, burn or hurt?
 The child said that they only itch and hurt a
little bit.
The History (HPI)
(Elicited from mother and child)
• Is anyone else around the child sick or have
similar skin problems?
– NO
• Does the child have any underlying illness or
condition ( Diabetes, HIV/AIDS, chemo,
gluccoicorticoid use, etc…) that causes
immune compromise?
– NO
• Has any attempt made to self treat the rash?
– NO
• Is the child currently on any medications?
– NO
The History (HPI)
(Elicited from mother and child)
• Does the child have any known allergies?
– NO
• Has the child been sick recently?
– A runny nose and nasal congestion for the
past week. No fever, sore throat, ear
aches, headaches, body aches, chills,
night sweats, SOB or cough.
• Has the child ever experienced this before?
– NO
The Physical Exam
• General: Non-toxic appearing, NAD, A&OX3
• Skin: Warm, moist
• Multiple yellowish-brown crusted lesions
approximately 1-3cm in diameter with a
slightly erythematous base.
• Several lesions around mouth and nose
most 1-2cm in diameter.
• One lesion on right forearm and one in the
right midclavicular region, both
approximately 3cm in diameter
• HEENT:
– Turbinates slightly erythematous
– Mild-moderate nasal congestion with clear
nasal discharge
– Rest of exam within normal limits
The Physical Exam
• NECK:
– Supple
– Submandibular and submental adenopathy-- soft, nontender, mobile
• CHEST:
– Lungs CTA B/L without adventitious sounds
– Symmetrical -No accessory mm use
• HEART:
– RRR
– No murmurs, gallops, clicks auscultated
• ABDOMEN:
– Positive bowel sounds x 4 quads
– Soft, nontender
– No masses, hepato-/spleno- megally
IMPETIGO
• The most common bacterial skin infection in
children
• Superficial infection of the epidermis
• Most commonly involves the face (mouth and nose),
extremities, hands, and neck
• Peak incidence in summer and early fall
• Children with poor hygiene and malnutrition
• Contagious and will spread from one part of the body
to another through scratching
• Usually appears on previously traumatized skin or
skin that has a preexisting break in its integrity
(psoriasis, eczema, atopic dermatitis)
IMPETIGO--Nonbullous form
• ETIOLOGY:
– 1. Staph (S.aureus) 2. Combo Strep and Staph 3.
Strep (S.pyogenes)
– Usually on predisposed skin (varicella, bites, cuts, burns)
• CLINICAL FEATURES:
– Discrete, fragile vesicles surrounded by an erythematous
border. The vesicles become pustular, rupture, and
discharge a honey colored fluid that quickly forms a crust
– Little or no erythema, pruritis, or constitutional symptoms
– Regional adenopathy (90%)
– Leukocytosis (50%)
IMPETIGO--Nonbullous form
IMPETIGO--Bullous Form
• ETIOLOGY:
– Staphlococcus aureus
– Occurs sporadically on intact skin as a
manifestation of localized toxin production
• CLINICAL PRESENTATION:
– Flaccid, transparent bullae that quickly become
purulent and rupture spontaneously
– Most commonly on the skin of moist intertriginous
areas
– No regional adenopathy, erythema, or
constitutional symptoms
IMPETIGO--Bollous Form
IMPETIGO--DIAGNOSIS
• History
• Physical exam
• Culture, gram stain, biopsy
using histopathic evaluation
when unsure
• Usually emperic
IMPETIGO--Treatment
• Mupirocin (Bactroban) ointment
– Apply to affected area TID for 10 days
• Cephalexin (Keflex)
– 25-50 mg/kg/day for 10 days for children
– 500 mg BID for adults
• Alternatives
– Pen VK
– Second generation Cephalosporins
– Macrolides
• Bullous Impetigo of a NB
– Oxicillin, Augmentin…PO
IMPETIGO--Complications
• Can persist for months if untreated
• Pigmentary changes with or without scarring
• Acute glomerulonephritis (Group-A- Beta hemolytic Strep)
– 3 weeks after pyoderma -children 2-6 years old
– headache, anorexia, dull back pain, edema and HTN, proteinuria,
hematuria, and RBC casts
• Cellulitis
– Rapidly spreading infection of the dermis and subcutaneous tissue
– Warmth, tenderness, localized erythema
– No sharply demarcated borders
• Lymphangitis
– Inflammation of the lymphatic channels from invasion by pathogenic
organisms (Group-A-Beta-hemolytic Strep)
– Erythematous, irregular linear streaks from primary site to regional
lymph nodes
ECTHYMA

• Deeper and more chronic infection than


impetigo
• More frequently on the legs
• S. pyogenes
• Initial vesicles with erythematous
base==>erode through dermis to form a
thick crusted ulcer with elevated margins
surrounded by a red rim.
• Tx= same as impetigo
Herpes simplex virus
• Initial episode with systemic symptoms
• Gingivostomatitis and adenopathy
• Painful erosions or ulcers on the lips, tongue,
gingivae, buccal mucosa, cheeks, and nose
• Initial inflammation, tenderness and/or itching
of the skin followed by grouped vesicles on an
erythematous base. They rupture to
leave a small cluster of erosions
• Diagnosis= Tzank test shows Multinucleated
giant cells
VARICELLA
• Prodrome of low grade fever, Upper
respiratory sxs, and mild malaise followed
by the appearance of a prurtic exanthem.
• Initially on trunk and scalp
• Tiny erythematous papules ==> thin-walled,
superficial central vesicles surrounded by
red halos ==> drying, umbillicated
appearance, and crust form
• Hallmark = three stages
• Peak in late fall through early spring
DERMATITIS
(Atopic and Contact)
• Redness, edema, vesiculation, scaling,
lichenification, pigmentation changes
• Eczema (Infantile)= red, itchy papules and
plaques that ooze and crust over the
cheeks, forehead, extremities, scalp, trunk
--usually symmetrical
• Contact Dermatitis=well/ demarcated
erythema, crusting, and/or blistering
– contact with irritant
Tinea Capitus
• Kerion form=raised, tender boggy plaques
or masses with pustules that stimulate
absess formation
• Occipital, postauricular, posterior cervical
adenopathy
• Involve the scalp or hair line
CONCLUSION
• From the case presentation, history, and PE the
diagnosis was IMPETIGO--Nonbullous form
• Although the presentation was similar to that of
ecthyma and bullous impetigo, all forms are
treated similarly
• The child was given Bactroban ointment TID for 10
days and Keflex po for 10 days
• Child kept out of school until he was on the oral
antibiotic for 24 hours
PATIENT EDUCATION
AND FOLLOW UP
• The mother was told to remove the scabs (with warm water soak
if needed) and to wash the areas with antibacterial soap before
ointment application.
• After ointment application, she was instructed to cover the lesions
with an adhesive bandage to avoid further spread and scratching.
• Mom was also advised to discourage the child from touching the
lesions and to constantly wash his hands with antibacterial soap.
• To prevent spread to family members, avoid sharing towels or
wash clothes with child.
• Advised that the lesions should heal within one week
• Advised to return if the impetigo worsens, is not completely
healed in one week, or the child develops a fever or sore throat
QUESTIONS???

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