Bladder Cancer

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The key takeaways are that bladder cancer is more common in men and cigarette smoking is a major risk factor. The most common type is urothelial carcinoma.

The common types of bladder cancer are urothelial carcinoma, squamous cell carcinoma, and adenocarcinoma. Urothelial carcinoma is the most common.

Some risk factors for bladder cancer include cigarette smoking, chemical exposure, age, sex, race, personal history, and family history.

BLADDER CANCER

INTRODUCTION

• Bladder cancer is a common type of cancer


that begins in the cells of the bladder
• More common site of cancer is the urinary
tract.
• 2.7 times more common in men. Men fourth
commonest cause of cancer.
Definition
• Bladder cancer

Bladder cancer refers to any of several


types of malignant growth of the urinary bladder.
CAUSES AND RISK FACTORS
 Cigarette smoking
 Chemical exposure at work

 Diet: Fried meats


Risk Factors

 Age: Seniors are at high risk of developing bladder


cancer.
 Sex: Men are three times more likely than women to
have bladder cancer.
 Race: whites have much higher risk of developing
cancer .
 Personal history of bladder cancer

 Family history of bladder cancer

 Chronic bladder inflammation

 Birth defects

 External beam radiation


Types
• Urothelial carcinoma: Urothelial carcinoma,
previously called transitional cell carcinoma, occurs in
the cells that line the inside of the bladder. Urothelial
carcinoma is the most common type of bladder cancer
• Squamous cell carcinoma: Squamous cell carcinoma
is associated with chronic irritation of the bladder
from an infection or from long-term use of a urinary
catheter. Squamous cell bladder cancer is rare.
• Adenocarcinoma: Adenocarcinoma begins in cells
that make up mucus-secreting glands in the bladder.
Adenocarcinoma of the bladder is very rare.
STAGES
CLINICAL MANIFESTATIONS

• Hematuria: This may be visible to the naked


eye or detectable only by microscope.
• Frequent urination
• Painful urination
• Back pain
Diagnosis
• History collection
• Physical examination
• Cystoscopy
• Biopsy
• Imaging
• Urine cytology
MANAGEMENT
 Transurethral resection with fulguration : In this
operation , an instrument is inserted through the
urethra and into the bladder . A small wire loop on the
end of the instrument then removes the tumor by
cutting it or with electrical current (fulguration).
 Radical cystectomy: In this operation the entire bladder
is removed ,it is removed as well as its surrounding
lymph nodes and other structure that may contain cancer.
 Sagmental or partial cystectomy : In this operation,
part of the bladder is removed .In men the standard
surgical procedure is a cysto prostactomy (removal of
the bladder and prostate ) with pelvic lymph
adenectomy .
 In women ,the standard surgical procedure is a radical
cystectomy with pelvic lymph adenectomy.
 Chemotherapy : In early bladder cancer chemotherapy
may be infused into the bladder through the urethra .
Drugs commonly used to treat bladder cancer include
thiotepa ,mitomycin and doxorubicin.
 Radiation therapy: Radiation may be given for small
muscle invasive bladder cancer, radiation therapy is also
used relive symptoms (palliative treatment) of advanced
bladder.
 Targeted therapy: To treat advanced cancer when other
treatments haven't helped
Immunotherapy
• This treatment uses bacillus Calmette-Guerin (BCG),
which was developed as a vaccine used to protect against
tuberculosis.
• BCG causes an immune system reaction that directs
germ-fighting cells to the bladder
NURSING MANAGEMENT

 Assist patient to minimize irritative


the voiding by fluid managementand
symptoms
bladder avoidance of
irritants.
 Administer urinary analgesics or antispasmodic
medications.
 Provide frequent small meals to minimizenausea
related chemotherapy .
 Monitor signs for hypertension .
 Monitor complete blood count.

 Assist the patient in positional changes to relive local


or generalized discomfort from bone metastasis .
Prevention
• Don't smoke
• Take caution around chemicals
• Choose a variety of fruits and vegetables.
• Healthy lifestyle
Complications
• Anemia
• Swelling of the ureters (hydronephrosis)
• Urethral stricture.
• Urinary incontinence.
• Erectile dysfunction in men.
• Sexual dysfunction in women.

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