Chain of Infection

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Chain of Infection

Healthcare Finals Concept


Chain of Infection

Certain conditions must be met in order for microorganisms and infectious


diseases to be transmitted from person to person. This process, known as the
chain of infection, only occurs if all six links in the chain are intact.
Links in the chain
Infectious Agent

These are the pathogens that cause


communicable diseases. This includes not only
bacteria, but also viruses, fungi and parasites. •Bacteria
The toxicity of these pathogens depends on
their number, potency, ability to enter and •Viruses
survive in the body, and host susceptibility.
•Parasites
Reservoir

Infectious pathogen reservoirs are habitats where •People


pathogens normally live, grow, and breed.
•Animals/Pets (dogs,
Animate reservoirs include people, insects, birds, and •cats, reptiles)
other animals. Inanimate reservoirs include soil, •Wild animals
water, food, feces, intravenous fluid, and equipment.
•Food
•Soil
•Water
Portal of Exit

The place where the organism leaves the reservoir,


such as the respiratory tract (nose, mouth), intestinal
•Mouth (vomit, saliva)
tract (rectum), urinary tract, or blood and other body
fluids. •Cuts in the skin
(blood)
•During diapering and
toileting stool
Mode of Transmission

The means by which an organism transfers from one


carrier to another by either direct transmission or
indirect transmission. •Contact (hands, toys,
sand)
•Droplets (when you
speak, sneeze or cough)
Direct
- In direct transmission, an infectious agent is transferred from a reservoir to
a susceptible host by direct contact or droplet spread.

•Direct contact - occurs through skin-to-skin contact, kissing, and sexual


intercourse.

•Droplet spread - refers to spray with relatively large, short-range aerosols


produced by sneezing, coughing, or even talking.
Indirect
- Indirect transmission refers to the transfer of an infectious agent from a reservoir to
a host by suspended air particles, inanimate objects (vehicles), or animate
intermediaries (vectors).

•Airborne transmission - occurs when infectious agents are carried by dust or droplet
nuclei suspended in air.
•Vehicleborne - Vehicles that may indirectly transmit an infectious agent include
food, water, biologic products (blood), and fomites (inanimate objects such as
handkerchiefs, bedding, or surgical scalpels).
•Vectorborne (mechanical or biologic) - Vectors such as mosquitoes, fleas, and ticks
may carry an infectious agent through purely mechanical means or may support growth
or changes in the agent.
Portal of Entry

The portal of entry refers to the manner in which a pathogen


enters a susceptible host.

Other portals of entry include the skin (hookworm), mucous


membranes (syphilis), and blood (hepatitis B, human •Mouth
immunodeficiency virus). •Cuts in the skin
•Eyes
Susceptible Host

The final link in the chain of infection is a susceptible host.


The person who is at risk for developing an infection from the •Babies
disease. Several factors make a person more susceptible to
disease including age (young people and elderly people •Children
generally are more at risk), underlying chronic diseases such •Elderly
as diabetes or asthma, conditions that weaken the immune •People with a weakened
system like
immune system
HIV, certain types of medications, invasive devices like
feeding tubes, and malnutrition. •Unimmunized people
Anyone
6 Links in the Chain
Infectious Agent

Reservoir

Portal of Exit

Mode of Transmission

Portal of Entry

Susceptible Host
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