Monkeypox
Monkeypox
Monkeypox
• It is a zoonotic disease that affects primarily animals and spread to humans. There are other
examples of zoonosis: Ebola virus, HIV, Smallpox, Cow pox, Salmonellosis.
• The Monkey pox caused by a virus that was first recorded in the 1950s when two colonies of
monkeys kept for research started showing symptoms similar to smallpox virus in Congo.
• The Monkeypox virus belongs to the same family, (Orthopox virus), which can also cause
smallpox and cowpox. The first positive human case of the monkeypox virus was identified in
the 1970s in the Democratic Republic of the Congo.
• To be noted that Smallpox similar to Monkey pox was the biggest killer in history. 500 million
deaths in 1oo years of existence, the last case was detected in October 1977 and eradicated in
1980 by vaccination. All known stocks of smallpox worldwide were destroyed or transferred to
two WHO-designated reference laboratories – the United States' (CDC) and the Soviet Union's
(now Russia’s) State Research Centre of Virology.
Symptoms and signs
• Fever, Headache.
• Muscle Pain, Chills, Fatigue.
• Swollen lymph nodes.
• Blistering Rash.
Diagnosis,Prevention,Outcome.
• Diagnosis: Through Clinical findings and PCR
• Treatment: Supportive, Antiviral Drugs.
• Prevention: Vaccination, In the U.S., two vaccines (JYNNEOS and ACAM2000)
• Outcome of the Disease:
• After healing, the scabs may leave pale to darker scars.
• Most people can recover from monkeypox on their own.
• The risk of death to the general population remains very low.
• Fatality rates have been reported as around 3.6% in West Africa and 10.6% in Central Africa.
• Most reported deaths have occurred in young children and people with HIV infection.
How does it Spread
• Time of exposure to onset of symptoms:
5 to 21 Days after exposure to the virus.
• Duration of illness: 2 to 4 weeks
• Transmission:
• Transmission from Animal to Human :
• Through infected animal bite or scratch, bush meat preparation, or by contact with an infected animal’s bodily
fluids or lesion material.
• Through broken skin, the respiratory tract, or the mucous membranes of the eyes, nose, or mouth.
• Transmission from Human to Human:
• The virus can spread by respiratory (airborne) contact or by direct contact with an infected person's bodily
fluids or during pregnancy from mother to fetus.
• Transmission can occur during sexual contact.
• Spread via fomites or through indirect contact with lesion material, contaminated beds, through inhalation.
• Risk factors for transmission include sharing a bed or room, or using the same utensils as an infected person.
Control Spreading