Scribd Logo
Upload

Welcome to Scribd!

  • 171 views

    Degeneration and Necrosis

    Uploaded by

    Carrie Rodriguez
    The document discusses several types of cell and tissue death (necrosis): - Coagulative necrosis results in pale, dry tissue that may become inflamed. Microscopically, there is decreased staining without nuclear structure. - Caseous necrosis causes soft, crumbly white masses where cellular outlines are lost, seen in tuberculosis. - Liquefactive necrosis fully digests cells by enzymes, causing a fluid-filled space after debris removal by white blood cells. It is associated with abscesses. - Gangrene and fat necrosis are also discussed as forms of tissue death.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPT, PDF or read online from Scribd

    Degeneration and Necrosis

    Uploaded by

    Carrie Rodriguez
    171 views64 pages
    The document discusses several types of cell and tissue death (necrosis): - Coagulative necrosis results in pale, dry tissue that may become inflamed. Microscopically, there is decreased staining without nuclear structure. - Caseous necrosis causes soft, crumbly white masses where cellular outlines are lost, seen in tuberculosis. - Liquefactive necrosis fully digests cells by enzymes, causing a fluid-filled space after debris removal by white blood cells. It is associated with abscesses. - Gangrene and fat necrosis are also discussed as forms of tissue death.

    Original Description:

    DISCLAIMER: I did not make or own this.

    Copyright

    © Attribution Non-Commercial (BY-NC)

    Available Formats

    PPT, PDF or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    The document discusses several types of cell and tissue death (necrosis): - Coagulative necrosis results in pale, dry tissue that may become inflamed. Microscopically, there is decreased staining without nuclear structure. - Caseous necrosis causes soft, crumbly white masses where cellular outlines are lost, seen in tuberculosis. - Liquefactive necrosis fully digests cells by enzymes, causing a fluid-filled space after debris removal by white blood cells. It is associated with abscesses. - Gangrene and fat necrosis are also discussed as forms of tissue death.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPT, PDF or read online from Scribd
    Download as ppt or pdf
    171 views64 pages

    Degeneration and Necrosis

    Uploaded by

    Carrie Rodriguez
    The document discusses several types of cell and tissue death (necrosis): - Coagulative necrosis results in pale, dry tissue that may become inflamed. Microscopically, there is decreased staining without nuclear structure. - Caseous necrosis causes soft, crumbly white masses where cellular outlines are lost, seen in tuberculosis. - Liquefactive necrosis fully digests cells by enzymes, causing a fluid-filled space after debris removal by white blood cells. It is associated with abscesses. - Gangrene and fat necrosis are also discussed as forms of tissue death.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPT, PDF or read online from Scribd
    Download as ppt or pdf
    You are on page 1of 64

    Cell Swelling

    Cell Swelling

    Cloudy Swelling

    Fatty Degeneration

    Fatty change

    Hyaline Degeneration

    Amyloidosis

    Amyloidosis

    Amyloidosis

    Amyloidosis

    Amyloidosis

    Lipofuscin, wear and tear pigment

    Anthracosis, lung

    Anthracosis

    anthracosis

    Silicosis

    Asbestosis

    Hematin

    Hemosiderin

    hemosiderin

    Bilirubin

    Bilirubin

    Lipofuscin

    Melanin

    Melanin

    Dystrophic Calcification

    Metastatic Calcification

    Iron

    Coagulative necrosis
     Macroscopic  The macroscopic appearance of an area of

    coagulative necrosis is a pale segment of tissue contrasting against surrounding well vascularised tissue and is dry on cut surface. The tissue may later turn red due to inflammatory response. The surrounding surviving cells can aid in regeneration of the affected tissue unless they are stable or permanent.

     Microscopic  The microscopic anatomy shows a lighter

    staining tissue (when stained with H&E) containing no nuclei with very little structural damage giving the appearance often quoted as 'ghost cells'. The decreased staining is due to digested nuclei which no longer show up as dark purple when stained with hematoxylin and removed cytoplasmic structures giving reduced amounts of intracellular protein reducing the usual dark pink staining cytoplasm with eosin.

    Coagulative necrosis

    Coagulative necrosis

    Caseous necrosis
     Caseous necrosis describes a form of

    biological tissue death, caseous meaning it has a cheese-like appearance. The dead tissue appears as a soft and white proteinaceous dead cell mass, all cellular outline is lost and tissue appears crumbly and cheeselike, usually seen in tuberculosis. Also called caseous degeneration.

    Caseous necrosis

    Caseous necrosis

    Caseous necrosis

    Caseous necrosis

    Caseous necrosis

    Caseous necrosis

    Caseous necrosis

    Caseous necrosis

    Caseous necrosis

     Liquefactive necrosis (or colliquative necrosis) is a

    type of necrosis which is characteristic of focal bacterial or fungal infections. In liquefactive necrosis, the affected cell is completely digested by hydrolytic enzymes, resulting in a soft, circumscribed lesion consisting of pus and the fluid remains of necrotic tissue. After the removal of cell debris by white blood cells, a fluid filled space is left. It is generally associated with abscess formation and is commonly found in the central nervous system

    Liquefactive necrosis

    Liquefactive necrosis

    Liquefactive necrosis

    Liquefactive necrosis

    Liquefactive necrosis

    Liquefactive necrosis

    Gangrene

    Gangrene

    Fat necrosis
    Fat necrosis is a form of necrosis characterized by the action upon fat by digestive enzymes.[1] In fat necrosis the enzyme lipase releases fatty acids from triglycerides. The fatty acids then complex with calcium to form soaps. These soaps appear as white chalky deposits.[2] It is usually associated with trauma of the pancreas or acute pancreatitis.[2][3] It can also occur in the breast[4] and neonates after a traumatic delivery.

    Fat necrosis

    Fat necrosis

    Fat necrosis

    Fibrinoid necrosis

    Fibrinoid necrosis

    Nuclear Death

    You might also like