Paper I MCQ's Physiology

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PHYSIOLOGY

PAPER-I

Basic concept ,genetics and


immunology
1. Protein synthesis occurs in:
a. Smooth ER
b. Golgi bodies
c. rough ER
d. lysosomes
2. The intracellular digestive system refers to:
a. Golgi apparatus
b. Mitochondria
c. Lysosomes
d. Endoplasmic reticulum
3. A major force affecting the distribution of water
and solutes in different body compartments is:
a. diffusion
b. osmosis
c. Active transport
d. Carrier type processes
4. Most of the body fluid is present in:
a. Extracellular compartment
b. Intracellular compartment
c. Transcellular compartment
d. Intravascular compartment
5. The exocytosis requires which ion?
a. sodium
b. potassium
c. calcium
d. magnesium

6. Deuterium oxide is used to measure volume of:
a. blood
b. total body water
c. extracellular fluid
d. intracellular fluid
7. Gap junctions are intercellular connections that:
a. primarily serve to keep cells separated and allow for
transport across a tissue barrier.
b. Serve as a regulated cytoplasmic bridge for sharing of
small molecules between cells.
c. Serve as a barrier to prevent protein movement within the
cellular membrane.
d. Are cellular components for constitutive exocytosis that
occurs between adjacent cells.
8. Synaptic signal involves:
a. endocrine signals
b. paracrine signals
c. autocrine signals
d. neurocrine signals
9. Sodium-potassium pump is characterized by all of
the following except:
a. Requires binding by only sodium and potassium for
its activation
b. Uses membrane bound ATPase as a carrier
molecule
c. Is responsible for maintaining high potassium and
low sodium concentration in the cell
d. accounts for a large part of the basal metabolism
10. Simple diffusion and facilitated diffusion share
which of the following characteristics:
a. can be blocked by specific inhibitors
b. do not require adenosine triphosphate
c. require transport protein
d. saturation kinetics
11. A molecule that produces an immune response is
a. Antigen
b. Antibody
c. Carcinogen
d. Mutagen
12. Antibodies are produced by

a. Histiocytes
b. Mast cells
c. Plasma cells
d. Fibroblasts
13. C5b of complement complex is known as:
a. opsonizing complex
b. chemotaxic complex
c. lytic complex
d. agglutinating complex
14. Which of the following applies to AIDS patients?
a. able to generate a normal antibody response.
b. Increased helper T cells
c. Increased secretion of interleukins
d. Decrease in helper T cells.
15. IL-2 is an important molecule in the immune
response. What is the function of IL-2?
a. Binds to and presents antigen
b. Stimulates proliferation of cytotoxic T cells
c. Kills virus-infected cells
d. Is required for replication
16. The first two weeks after conception are known
as the

a. germinal stage
b. embryonic stage
c. fetal stage
17.The fertilized egg is known as
a. Morula
b. Blastocyst
c. Zygote
18. In males the__________________ persists, and
forms the tube of the epididymis.
a. Pronephric duct
b. Müllerian ducts
c. Wolffian duct
19. This is a 12-16 cells stage
a. Morula
b. Blastocyst
c. Zygote
20. Most boys start developing sexually between the ages of :
a. 8 to 14
b. 10 to 13
c. 20 -24
21. Absolute refractory period:
a. Begins from the time the firing level is reached
until the repolarization is complete
b. During this period stimulus stronger than usual
can cause excitation
c. During this period more sodium channels open up.
d. During this period no stimulus, no matter how
strong can initiate the fresh impulse.
22. Resting nerve membrane is more permeable to
K+ than to Na+ by:
a. 1-5 times
b. 50-100 times
c. 20-50 times
d. 200-500 times
23. Magnitude of resting membrane potential from
tissue to tissue ranges from …………….. mV
a. -50 to -70
b. -40 to -90
c. -10 to -100
d. -70 to -100
24. All or none law refers to:
a. Resting Potential
b. Action Potential
c. Excitatory Post synaptic potential
d. Strength of contraction
25. What is the equilibrium potential for Cl- across
the plasma membrane of this cell?
a. O mV
b. -122 mV
c. -61 mV
d. +122 mV
26. Homeostasis means
a. Maintenance of constant internal environment.
b. Clotting of blood
c. Maintenance of constant external environment
d. None of the above
27. Which of the following is not the example of
positive feedback mechanism?
a. Clotting of blood
b. Parturition reflex
c. Regulation of normal serum T3/T4
d. Milk let down reflex
28. Internal environment of the body is composed by:
a. ECF
b. ICF
c. Interstitial fluid
d. Total body water
29. Which of the following factor doesn’t play any role
in maintenance of Resting Membrane Potential?
a. Leaky K+ channels
b. Na+/K+ pump
c. Unequal distribution of ions across the cell
membrane
d. Voltage gated Na+ channels
30. The point at which a run away spike potential is
initiated is called:
a. Local response
b. Depolarization
c. Firing Level
d. Repolarization
ANSWERS
1.C 16. a 26. a
2.C 17. c 27. c
3. a 18. c 28. a
4. b 19. a 29. d
5. c 20. b 30. c
6. b 21. d
7.b 22. b
8. d 23. C
9. a 24. b
10. b 25. C
11. a
12. c
13. a
14. d
15. b

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