Tuberculosis

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Tuberculosis

• Tuberculosis (TB) is an infectious disease that most often affects the


lungs and is caused by a certain type of bacteria. It is spread through
the air when infected people cough, sneeze or expectorate.
• SymptomsPeople with latent TB infection do not feel sick and are not
contagious. Only a small proportion of infected people develop TB and
show symptoms. Infants and children are at increased risk.People
who:suffer from diabetes (high blood sugar);have a weakened immune
system (for example, people with HIV infection or AIDS);suffer from
malnutrition;use tobacco.
PreventionTo prevent TB infection and spread, you must do the following:If you
experience symptoms such as a persistent cough, fever and unexplained weight loss, seek
medical help as treating TB early can help stop the disease from spreading and improve
your chances of recovery.Get tested for TB infection if you are at increased risk, for
example if you have HIV infection or have contact with people with TB at home or at
work.If you are prescribed treatment to prevent TB, complete the entire course.If you
have TB, practice good cough hygiene, including avoiding contact with other people and
wearing a mask, covering your mouth and nose when coughing or sneezing, and properly
disposing of sputum and used tissues.Specific measures such as the use of respirators and
ventilation are essential to control the spread of infection in health care and other settings.
• DiagnosticsWHO recommends rapid molecular diagnostic tests as
the initial diagnostic test for all people with signs and symptoms of
TB.WHO recommends Xpert MTB/RIF Ultra and Truenat as
diagnostic rapid tests. These tests have high diagnostic accuracy
and will lead to significant improvements in the early detection of
TB and drug-resistant TB.A tuberculin skin test (TST) or an
interferon gamma release assay (IGRA) may be used to identify
people with infection.Diagnosing multidrug-resistant TB and other
resistant forms of TB (see section on multidrug-resistant TB below),
as well as HIV-associated TB, can be difficult and
expensive.Tuberculosis is especially difficult to diagnose in children.
• TreatmentTuberculosis should be treated with antibiotics.
Treatment is recommended for both TB infection and TB disease.The
most commonly used antibiotics
are:isoniazid,rifampicin,pyrazinamide,ethambutol,streptomycin.For
effective treatment, these drugs must be taken daily for 4–6
months. It is dangerous to stop taking medications prematurely or
without consulting a doctor. This may allow the TB pathogen that
persists in the body to become drug resistant.Tuberculosis that does
not respond to standard drugs is called drug-resistant TB and
requires the use of more toxic drugs.

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