Stress Physiology
Stress Physiology
Stress Physiology
Dr Pramod Kumar
Department of Veterinary Physiology
Bihar Veterinary College, Patna
Stress
Any event which an individual finds difficult to
cope with is called a stressor.
The stress may be physical, psychological or
socio-culture.
Animals have to endure many stressors in
their natural environments. For eg, food
shortages, survivability from predator or
parasites, conflicts with group members,
fluctuations in food and water availability and
temperature.
Stress
• Stress = Nervous system + endocrine system
to prepare the body for a challenge.
• Physiological response - The fight-or-flight
sympathetic nervous system response works
to keep alive, like release of endorphins,
dopamine and other neurotransmitters
• Autonomic nervous system :
• Effects via PSNS (Trophotropic response) are
inhibition, slowing and restorative functions
• Effects of neural activation via SNS (ergotropic
response) are generalized arousal.
• Adrenocorticotropic Hormone, Corticotropin
Releasing Hormone and Glucocorticoid
increases energy and reduce inflammation,
histamines and immunity at ACTH axis
• General Adaptation Syndrome was proposed
by Hans Seyle (1956 ) as an integrative model
for the stress response. It is tri- phasic
phenomenon which involves alarm, resistance
and exhaustion phase
• Epinephrine effects heart rate and stroke
volume: acts on blood and resources to non-
essentials like guts, reproductive, skin, heart,
brain, lungs, skeletal muscle
• Other effects: release stored nutrients from
liver and fat into blood stream send WBCs to
battle stations in skin during injury
• Oxytocin —released during stress and makes
us seek out social connections
• Stress – released less cortisol and more
oxytocin (vasodilation) and repairs damaged
cardiac muscle from stress, combats
inflammation