"Among the validated rhabdomyosarcoma genes, EZH2, CDK6, and
RIPK2 are particularly worthy of further investigation because there are already drugs that target these genes that are either FDA-approved or in clinical trials," Dr.
Budreiko et al., "The expression of CCN2, IQSEC, RSPO1, DNAJC15,
RIPK2, IL13RA2, IRS1, and IRS2 genes in blood of obese boys with insulin resistance," Fiziologicheskii Zhurnal, vol.
Genes P value COL4A1 3.17E-08 PCDH17 7.47E-08 PECAM1 2.07E-07 IGFBP5 2.73E-07 CAV1 2.75E-07 KCNJ8 3.49E-07 PIK3R3 3.53E-07 LCN2 3.77E-07 COL6A3 4.13E-07 COL4A2 4.78E-07 HEG1 5.51E-07 CD93 6.32E-07 ADAM9 6.36E-07
RIPK2 9.92E-07 AMN 1.11E-06 ACVR1 1.11E-06 CALU 1.17E-06 CXCL6 1.32E-06 TMEM158 1.63E-06 TIMP3 1.70E-06 Table 2.