Results: The promoters of the defensin A4 and
cecropin B1 genes produced robust expression of luciferase and GFP in the Ae.
HP leads to a micro-ecological imbalance principally because of its production of an antibacterial peptide called
cecropin. This peptide can cause other bacteria to undergo "autogenic autolysis" [28].
[82], when they successfully transformed a commensal symbiont in the hindgut lumen of Rhodnius prolixus, Rhodococcus rhodnii, to express the
cecropin A protein to kill the causative agent of Chagas disease, and Trypanosoma cruzi inside their host.
The AMP
cecropin AD protected weaned piglets against Escherichia coli infection via increasing immune status [24].
Because of the toxic characters of some effective AMPs, hybride peptides such as CAMA (
Cecropin (1-7)-melittin A (2-9) amide) are designed for increasing the antimicrobial activity while decreasing toxicity.
Cecropin peptide family is another subclass of AMPs, mainly derived from roundworms in animal intestinal tracts [13,14].
ni based on antimicrobial peptide gene transcription was determined by testing attacin,
cecropin, gloverin, lebocin, lysozyme, peptidoglycan recognition protein (PGRP), gallerimycin, and defensin (Tamez-Guerra et al.
Expression of a Synthesized Gene Encoding Cationic Peptide
Cecropin B in Transgenic Tomato Plants Protects against Bacterial Diseases.
Inducible resistance of fish bacterial pathogens to the antimicrobial peptide
cecropin B.
(1989) found that an antimicrobial synthetic hybrid peptide (
cecropin A-melittin) showed bactericidal effect against S.