Temperature-dependent structural and functional properties of a mutant (F71L) αA-crystallin: molecular basis for early onset of age-related cataract (Q24297386)

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Language	Label	Description	Also known as
English	Temperature-dependent structural and functional properties of a mutant (F71L) αA-crystallin: molecular basis for early onset of age-related cataract	scientific article

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scholarly article

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Temperature-dependent structural and functional properties of a mutant (F71L) αA-crystallin: molecular basis for early onset of age-related cataract (English)

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structural biology

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identical protein binding

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GOA release 2020-03-11

author name string

Vakdevi Validandi

1

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V Sudhakar Reddy

2

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P N B S Srinivas

3

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Niklaus H Mueller

4

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S G Bhagyalaxmi

5

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T Padma

6

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J Mark Petrash

7

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G Bhanuprakash Reddy

8

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language of work or name

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publication date

15 December 2011

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585

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24

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3884-9

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The thermal structural transition of α-crystallin inhibits the heat induced self-aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

19 March 2017

Morphological characterization of the Alpha A- and Alpha B-crystallin double knockout mouse lens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

19 March 2017

AlphaB-crystallin in lens development and muscle integrity: a gene knockout approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

19 March 2017

Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

19 March 2017

Mechanism of small heat shock protein function in vivo: a knock-in mouse model demonstrates that the R49C mutation in alpha A-crystallin enhances protein insolubility and cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

19 March 2017

Phe71 is essential for chaperone-like function in alpha A-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

19 March 2017

Cat-Map: putting cataract on the map

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

27 September 2017

Importance of eye lens α‐crystallin heteropolymer with 3:1 αA to αB ratio: Stability, aggregation, and modifications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

27 September 2017

A novel mutation (F71L) in alphaA-crystallin with defective chaperone-like function associated with age-related cataract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

27 September 2017

Modulation of alpha-crystallin chaperone activity: a target to prevent or delay cataract?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

27 September 2017

Chaperone-like activity and hydrophobicity of alpha-crystallin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

27 September 2017

A transgenic mouse model for human autosomal dominant cataract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

27 September 2017

Ageing and vision: structure, stability and function of lens crystallins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

27 September 2017

Molecular genetics of age-related cataract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

27 September 2017

Important Causes of Visual Impairment in the World Today

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

27 September 2017

Alpha-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

27 September 2017

A positive charge preservation at position 116 of alpha A-crystallin is critical for its structural and functional integrity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

27 September 2017

Mutation R120G in alphaB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

27 September 2017

Identification of 1,1'-bi(4-anilino)naphthalene-5,5'-disulfonic acid binding sequences in alpha-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

30 May 2018

Mixed oligomer formation between human alphaA-crystallin and its cataract-causing G98R mutant: structural, stability and functional differences

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.10.049

21 January 2018

Thermally induced disintegration of the oligomeric structure of alphaB-crystallin mutant F28S is associated with diminished chaperone activity

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.10.049

21 January 2018

The alphaA-crystallin R116C mutant has a higher affinity for forming heteroaggregates with alphaB-crystallin

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.10.049

21 January 2018

Effects of congenital cataract mutation R116H on alphaA-crystallin structure, function and stability

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.10.049

21 January 2018

Insights into hydrophobicity and the chaperone-like function of alphaA- and alphaB-crystallins: an isothermal titration calorimetric study.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.10.049

21 January 2018

Cataract-causing alphaAG98R mutant shows substrate-dependent chaperone activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103624

29 November 2018

Synthesis and characterization of a peptide identified as a functional element in alphaA-crystallin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22085609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation of R116C results in highly oligomerized alpha A-crystallin with modified structure and defective chaperone-like function

1 reference

https://pubmed.ncbi.nlm.nih.gov/22085609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chaperone-like activity and quaternary structure of alpha-crystallin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22085609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temperature‐induced exposure of hydrophobic surfaces and its effect on the chaperone activity of α‐crystallin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22085609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chaperone-like activity and temperature-induced structural changes of alpha-crystallin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22085609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of a hereditary cataract phenotype. Mutations in alphaA-crystallin activate substrate binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/22085609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the single point genetic mutation D54G on muscle creatine kinase activity, structure and stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/22085609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance of alpha-crystallin heteropolymer with a 3:1 alphaA/alphaB ratio: chaperone-like activity, structure and hydrophobicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22085609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temperature-dependent coaggregation of eye lens αB- and β-crystallins

1 reference

https://pubmed.ncbi.nlm.nih.gov/22085609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temperature-dependent chaperone activity and structural properties of human alphaA- and alphaB-crystallins

1 reference

https://pubmed.ncbi.nlm.nih.gov/22085609

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.FEBSLET.2011.10.049

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