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- Le ribociclib (vendu sous les marques Kisqali et Kryxana), commercialisé par Novartis, est un inhibiteur de la cycline D1/CDK4 et CDK6, et est utilisé pour le traitement de certains types de cancer du sein. (fr)
- Ribociclib, sold under the brand name Kisqali and Kryxana marketed by Novartis, is an inhibitor of cyclin D1/CDK4 and CDK6, and is used for the treatment of certain kinds of breast cancer. Ribociclib is a kinase inhibitor indicated in combination with: an aromatase inhibitor for the treatment of pre/perimenopausal or postmenopausal women with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer, as initial endocrine-based therapy; or fulvestrant for the treatment of postmenopausal women with HR-positive, HER2-negative advanced or metastatic breast cancer, as initial endocrine-based therapy or following disease progression on endocrine therapy. It is also being studied as a treatment for other drug-resistant cancers. It was developed by Novartis and Astex Pharmaceuticals. Ribociclib is currently the only CDK4/6 inhibitor with a proven benefit on overall survival across all three Phase III trials of the MONALEESA clinical program with different endocrine therapy partners, regardless of menopausal status or line of therapy. The European Society of Medical Oncology (ESMO) assigned the highest score on the 'Magnitude of Clinical Benefit Scale' for Kisqali. (en)
- Ribociclib, comercializado sob a marca Kisqali, é um medicamento inibidor da / e usado no tratamento de alguns tipos de cancro da mama. Está também a ser estudado como tratamento para outros tipos de cancro resistentes a fármacos. Foi desenvolvido pela Novartis e . (pt)
- 瑞博西利(英語:Ribociclib)商品名擊癌利(KISQALI)是一種CDK4/6抑制劑類型的乳腺癌藥物,由和诺华制药研发。可使用的對象為:賀爾蒙接受體陽性、HER2陰性患者,以及停經後晚期乳腺癌患者。 (zh)
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- Le ribociclib (vendu sous les marques Kisqali et Kryxana), commercialisé par Novartis, est un inhibiteur de la cycline D1/CDK4 et CDK6, et est utilisé pour le traitement de certains types de cancer du sein. (fr)
- Ribociclib, comercializado sob a marca Kisqali, é um medicamento inibidor da / e usado no tratamento de alguns tipos de cancro da mama. Está também a ser estudado como tratamento para outros tipos de cancro resistentes a fármacos. Foi desenvolvido pela Novartis e . (pt)
- 瑞博西利(英語:Ribociclib)商品名擊癌利(KISQALI)是一種CDK4/6抑制劑類型的乳腺癌藥物,由和诺华制药研发。可使用的對象為:賀爾蒙接受體陽性、HER2陰性患者,以及停經後晚期乳腺癌患者。 (zh)
- Ribociclib, sold under the brand name Kisqali and Kryxana marketed by Novartis, is an inhibitor of cyclin D1/CDK4 and CDK6, and is used for the treatment of certain kinds of breast cancer. Ribociclib is a kinase inhibitor indicated in combination with: an aromatase inhibitor for the treatment of pre/perimenopausal or postmenopausal women with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer, as initial endocrine-based therapy; or fulvestrant for the treatment of postmenopausal women with HR-positive, HER2-negative advanced or metastatic breast cancer, as initial endocrine-based therapy or following disease progression on endocrine therapy. It is also being studied as a treatment for other drug-resistant cancers. I (en)
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- Ribociclib (fr)
- Ribociclib (en)
- Ribociclib (pt)
- 瑞博西利 (zh)
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