Table 2: Frequency of
alleles and genotypes of the FOXO3 SNP rs2802288 and Minor
Allele Frequency (MAF).
Peak height of SNP
alleles in the sequencing map and
allele frequencies which are estimated by MWsnap are shown in Table II.
Of the 33 different combinations, the highest combinations observed in SHWs were 'null, 6+8, 2.1+10.5' followed by 'null, 6+8, 1.5+10' and '2*, 6+8, 2+12', while, the Pakistani cultivars and land races harbored 'null, 20, 12+2' and '1, 7+8, 2+12'
alleles.
Progression to AIDS has been strongly associated with the human leukocyte antigen B (HLA-B)
alleles, particularly HLA-B*57 and HLA-B*27
allele groups (protection), and HLA-B*35 (susceptibility), due to the restricted recognition of HIV epitopes by cytotoxic immune system cells [4].
The present data explains prevalence of
alleles and genotypes frequency of CAT-21A/T (rs7943316) gene polymorphism in healthy individuals.
HLA-DRB1
alleles and genotypes in patients with relapsing-remitting multiple sclerosis from western Mexico: a pilot study
The protective FOXO3
allele (G
allele) is associated with longevity with one G
allele (GT genotype) doubling the odds to live to 100 and two G
alleles (GG genotype) tripling the odds to live to 100.
The chi-square test ([chi square]) was applied to analyze the accordance with Hardy-Weinberg equilibrium and the differences in the distribution of
alleles and genotypes.
Given the need for routine HLA genotyping for histocompatibility testing, the Immunogenetics community has characterized over 14000 named HLA
alleles using a variety of techniques including traditional serological approaches and more recent DNA-based methodologies including restriction fragment length polymorphism (RFLP) analysis, PCR-sequence specific oligonucleotide probes (PCR-SSOP), sequence specific primer PCR (SSP-PCR), Sanger sequence based typing (SBT) and most recently next generation sequencing (NGS) (8-19).