tricyclic

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tri·cyc·lic

(trī-sĭk′lĭk, -sī′klĭk)

adj.

Having or being a molecular structure that contains three closed rings: a tricyclic molecule.

A tricyclic antidepressant drug.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

tricyclic

(traɪˈsaɪklɪk)

adj

(Chemistry) (of a chemical compound) containing three rings in the molecular structure

(Pharmacology) an antidepressant drug having a tricyclic molecular structure

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

tri•cy•clic

(traɪˈsaɪ klɪk, -ˈsɪk lɪk)

adj.

1. pertaining to or embodying three cycles.

2. having a three-ring chemical structure.

3. Also called tricy′clic antidepres′sant. any of a group of pharmacologically active substances that share a common three-ring structure, used to treat depression and cocaine abuse.

[1890–95]

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Noun

tricyclic - an antidepressant drug that acts by blocking the reuptake of norepinephrine and serotonin and thus making more of those substances available to act on receptors in the brain

tricyclic antidepressant, tricyclic antidepressant drug

amitriptyline, amitriptyline hydrochloride, Elavil - a tricyclic antidepressant drug (trade name Elavil) with serious side effects; interacts with many other medications

antidepressant, antidepressant drug - any of a class of drugs used to treat depression; often have undesirable side effects

clomipramine - a tricyclic antidepressant drug

desipramine - a tricyclic antidepressant drug that activates the psychomotor system

Adapin, doxepin, doxepin hydrochloride, Sinequan - a tricyclic antidepressant (trade names Adapin and Sinequan) with numerous side effects (dry mouth and sedation and gastrointestinal disturbances)

Imavate, imipramine, impramine hydrochloride, Tofranil - a tricyclic antidepressant (trade names Imavate and Tofranil) used to treat clinical depression

nortriptyline, Pamelor - a tricyclic antidepressant drug (trade name Pamelor) used along with psychotherapy to treat dysthymic depression; may interact dangerously if taken with other drugs

protriptyline - tricyclic antidepressant used to treat clinical depression

Surmontil, trimipramine - tricyclic antidepressant drug (trade name Surmontil) used to treat depression and anxiety and (sometimes) insomnia

References in periodicals archive ?

Tricyclic antidepressants are an example of this type of drug, as are anticonvulsants.

Neuropathic pain syndromes. (Pain)

In a study comparing 38 depressed children receiving another tricyclic, imipramine, with controls on a placebo, Puig-Antich similarly found no advantage for the antidepressant drug.

Growing up sad: depression in children attracts scrutiny

Patients on mirtazapine (Remeron), reboxetine (Vestra), and quetiapine (Seroquel) displayed substantially less psychomotor impairment and scored substantially higher on the standardized tests of global driving ability used in Germany than did patients on tricyclic antidepressants, selective serotonin reuptake inhibitors (SSRIs), or venlafaxine (Effexor), Dr.

Fitness to drive depends on antidepressant type

Off-label use of systemic therapies usually starts with tricyclic antidepressants, most often amitriptyline.

Comprehensive treatment essential for vulvodynia

The analysis included patients who were treated with six different, selective serotonin reuptake inhibitors, including paroxetine (Paxil) and fluoxetine; two tricyclic antidepressants, amitriptyline and doxepin; and venlafaxine (Effexor), a selective norepinephrine reuptake inhibitor.

Antidepressant benefit may show within 2 weeks

Desmopressin (DDAVP) and tricyclic drugs reduce the number of wet nights by 1 to 2 per week during treatment, although the effect is not sustained after treatment is finished (SOR: A, based on a SR of homogeneous RCTs).

What is the best treatment for nocturnal enuresis in children?

A number of treatments are available for women with postpartum depressive disorder, including tricyclic antidepressants, monoamine oxidase inhibitors, selective serotonin reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, and hormone therapy.

Don't Miss Maternal Depression After Delivery

Those currently taking an antianxiety drug with effects extending over several days (including Valium), a tricyclic antidepressant (the most commonly used group of drugs to treat depression) or an antipsychotic were substantially more likely to have had a hip fracture.

Treating the mind, risking the body

ISTANBUL, TURKEY -- The use of tricyclic antidepressants to treat depression and /or anxiety was associated with a sharply increased risk of metabolic syndrome, compared with other antidepressant classes in a large prospective Dutch cohort study.

Tricyclics are associated with metabolic syndrome

In the selection of pharmacotherapy, a selective serotonin reuptake inhibitor (SSRI) would be the first choice for younger women or postmenopausal women on hormone therapy, while a tricyclic antidepressant may be more effective in men and older women not taking hormones, said Dr.

Consider key gender differences when treating depression

Most patients with diabetic peripheral neuropathic pain will experience significant relief and improved quality of life when treated with tricyclic antidepressants, duloxetine, controlled-release oxycodone, pregabalin, or a combination of these agents, according to new treatment guidelines issued by the American Society of Pain Educators.

Be persistent in treating diabetic neuropathic pain

Tricyclic antidepressants, anticonvulsants, and capsaicin reduce the pain of diabetic neuropathy; limited data suggests that lidocaine patches may also be efficacious.