Mark Jensen
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Papers by Mark Jensen
representation of aspects of neurological diseases that are relevant to their treatment and study. ND is a
representational tool that addresses the need for unambiguous annotation, storage, and retrieval of data associated
with the treatment and study of neurological diseases. ND is being developed in compliance with the Open
Biomedical Ontology Foundry principles and builds upon the paradigm established by the Ontology for General
Medical Science (OGMS) for the representation of entities in the domain of disease and medical practice. Initial
applications of ND will include the annotation and analysis of large data sets and patient records for Alzheimer’s
disease, multiple sclerosis, and stroke.
Description: ND is implemented in OWL 2 and currently has more than 450 terms that refer to and describe
various aspects of neurological diseases. ND directly imports the development version of OGMS, which uses BFO 2.
Term development in ND has primarily extended the OGMS terms ‘disease’, ‘diagnosis’, ‘disease course’, and
‘disorder’. We have imported and utilize over 700 classes from related ontology efforts including the Foundational
Model of Anatomy, Ontology for Biomedical Investigations, and Protein Ontology. ND terms are annotated with
ontology metadata such as a label (term name), term editors, textual definition, definition source, curation status,
and alternative terms (synonyms). Many terms have logical definitions in addition to these annotations. Current
development has focused on the establishment of the upper-level structure of the ND hierarchy, as well as on the
representation of Alzheimer’s disease, multiple sclerosis, and stroke. The ontology is available as a version-controlled
file at http://code.google.com/p/neurological-disease-ontology along with a discussion list and an issue tracker.
Conclusion: ND seeks to provide a formal foundation for the representation of clinical and research data pertaining
to neurological diseases. ND will enable its users to connect data in a robust way with related data that is
annotated using other terminologies and ontologies in the biomedical domain.
representation of aspects of neurological diseases that are relevant to their treatment and study. ND is a
representational tool that addresses the need for unambiguous annotation, storage, and retrieval of data associated
with the treatment and study of neurological diseases. ND is being developed in compliance with the Open
Biomedical Ontology Foundry principles and builds upon the paradigm established by the Ontology for General
Medical Science (OGMS) for the representation of entities in the domain of disease and medical practice. Initial
applications of ND will include the annotation and analysis of large data sets and patient records for Alzheimer’s
disease, multiple sclerosis, and stroke.
Description: ND is implemented in OWL 2 and currently has more than 450 terms that refer to and describe
various aspects of neurological diseases. ND directly imports the development version of OGMS, which uses BFO 2.
Term development in ND has primarily extended the OGMS terms ‘disease’, ‘diagnosis’, ‘disease course’, and
‘disorder’. We have imported and utilize over 700 classes from related ontology efforts including the Foundational
Model of Anatomy, Ontology for Biomedical Investigations, and Protein Ontology. ND terms are annotated with
ontology metadata such as a label (term name), term editors, textual definition, definition source, curation status,
and alternative terms (synonyms). Many terms have logical definitions in addition to these annotations. Current
development has focused on the establishment of the upper-level structure of the ND hierarchy, as well as on the
representation of Alzheimer’s disease, multiple sclerosis, and stroke. The ontology is available as a version-controlled
file at http://code.google.com/p/neurological-disease-ontology along with a discussion list and an issue tracker.
Conclusion: ND seeks to provide a formal foundation for the representation of clinical and research data pertaining
to neurological diseases. ND will enable its users to connect data in a robust way with related data that is
annotated using other terminologies and ontologies in the biomedical domain.