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Duygu Altuntas

Zonguldak Bülent Ecevit University, Medicine, Faculty Member

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Halil Erdem Özel

Ali Baran Budak

Emine Samdancı

MARMARA ÜNİVERSİTESİ

Bayram Veyseller

Bezmialem Vakif University

University of Virginia

Eskisehir Osmangazi University, Turkey

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Papers by Duygu Altuntas

Effects of polymer-based, silver nanoparticle-coated silicone splints on the nasal mucosa of rats

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, Jan 18, 2016

Infection is a serious complication after nasal packing that otolaryngologists seek to avoid. The... more Infection is a serious complication after nasal packing that otolaryngologists seek to avoid. The aim of this study is to investigate the use of silver (Ag) nanoparticle, which serves as antimicrobial agents, with nasal tampons. The study design is an experimental animal model and the setting is tertiary referral center. Twenty-four rats were randomized into the following four groups: (1) control group (n = 6); (2) silicone nasal splint (SNS) group (n = 6); (3) polypropylene-grafted polyethylene glycol (PP-g-PEG) amphiphilic graft copolymer-coated SNS group (n = 6); and (4) Ag nanoparticle-embedded PP-g-PEG (Ag-PP-g-PEG) amphiphilic graft copolymer-coated SNS group (n = 6). These tampons were applied to rats for 48 h, after which they were removed in a sterile manner, and the rats were sacrificed. The nasal septa of the rats were excised, and assessments of tissue changes in the nasal mucosa were compared among the groups. The removed tampons were microbiologically examined, a...

The effects of surgery type and different ossiculoplasty materials on the hearing results in cholesteatoma surgery

European Archives of Oto-Rhino-Laryngology, 2016

To investigate the effects of surgery type [intact canal wall (ICW) or canal wall down (CWD) mast... more To investigate the effects of surgery type [intact canal wall (ICW) or canal wall down (CWD) mastoidectomy] and different ossiculoplasty materials on hearing outcome in single-staged cholesteatoma surgery. A retrospective case-control study. A total of 116 cases (97 adults, 29 children) underwent surgery, including ossiculoplasty, between 2012 and 2015 for cholesteatoma. Patients who had undergone surgery for the first time, and whose grafts were successful, were included in the study. Patients with adhesive otitis media, unsuccessful grafts, revision and recurrent cases, radical mastoidectomy, and craniofacial anomalies were excluded. Audiogram examinations of the enrolled patients were performed 3-6 months after surgery, and the audiometric results were analyzed according to the criteria of the American Academy of Otolaryngology, Head and Neck Surgery. All ossiculoplasties were performed during the first operation. The preoperative average air-bone gap (ABG) of the patients was decreased from 31.37 ± 10.1 to 27.42 ± 10.4 dB; this decrease was found to be highly significant (p = 0.0001). Concerning the ICW

Reply to the letter to the editor ''in response to: a better design is needed for clinical studies of chronic tympanic membrane perforations using biological materials'' 10.1007/s00405-016-4019-0

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, Nov 1, 2016

Design of TENS Electrodes Using Diff erent Production Techniques

Tekstilec, 2016

Transcutaneous electrical nerve stimulation (TENS) treatment has been widely used in physical the... more Transcutaneous electrical nerve stimulation (TENS) treatment has been widely used in physical therapy to relieve diff erent types of pain. The TENS therapy is a non-invasive method applied with general types of electrodes, i.e. carbon and self-adhesive hydrogel electrodes. These electrodes are reusable, which might cause hygiene problems. In this study, two diff erent types of textile TENS electrodes were designed and produced with the sewing and embroidering technique using conductive yarn. Afterwards, the resistance values of produced electrodes were measured and compared to conventional carbon and self-adhesive hydrogel electrodes. Furthermore, the designed electrodes were connected to a commercially available TENS device and current transmission from the electrodes was tested on subjects.

Pretreatment Neutrophil-Lymphocyte Ratio in Salivary Gland Tumors Is Associated with Malignancy

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, Dec 19, 2016

To assess pretreatment levels in the counts and percentages of leukocytes and the neutrophil-lymp... more To assess pretreatment levels in the counts and percentages of leukocytes and the neutrophil-lymphocyte ratio (NLR) in benign and malignant salivary gland tumors (SGTs) while investigating whether NLR is an inflammatory marker for distinguishing low- from high-grade parotid gland tumors. Case series with chart review. Tertiary referral center. This study was performed on 182 patients with SGTs (age range: 16-87 years; 93 male and 89 female) who were treated between January 2010 and May 2015. Pretreatment counts and percentages of leukocytes and NLR were measured preoperatively in benign and malignant tumors. Mean neutrophil percentage (63.50% ± 12.11% vs 58.76% ± 8.20%, P = .008) and NLR (3.29 ± 3.13 vs 2.13 ± 1.26, P = .008) were significantly higher in patients with malignant SGTs than in patients with benign SGTs. Mean lymphocyte count (2.42 ± 0.72 10(3)/mm(3) vs 1.97 ± 0.87 10(3)/mm(3), P < .001) and percentage (30.67% ± 7.68% vs 26.86% ± 10.15%, P = .011) were lower in patie...

Design of TENS electrodes using conductive yarn

International Journal of Clothing Science and Technology, 2016

Purpose – The purpose of this paper is to develop textile-based transcutaneous electrical nerve s... more Purpose – The purpose of this paper is to develop textile-based transcutaneous electrical nerve stimulation (TENS) electrodes using conductive yarn to bring a solution to uncomfortable feelings and hygiene problems of conventional conductive hydrogel electrodes. It proposes washing process, resistance measurements and subjective tests to evaluate the performance of the developed textile-based electrode. Design/methodology/approach – In this study, six different textile electrode pairs were designed and produced with different patterns. Designed electrodes were washed for ten times. In order to evaluate the effect of pattern differences and washing process on electrode performances, two different tests were realized before and after washing. The first of these tests is resistance measurement with a multimeter, and the second one is subjective test carried out on subjects. Findings – The results obtained from resistance measurements indicated that the pattern differences cause resista...

Difficult septal deviation cases: open or closed technique?

Brazilian Journal of Otorhinolaryngology, 2017

The aim of this study is to compare the functional aspects of open technique (OTS) and endonasal ... more The aim of this study is to compare the functional aspects of open technique (OTS) and endonasal septoplasty (ENS) in ''difficult septal deviation cases''. Methods: 60 patients with severe nasal obstruction from S-shaped deformities, multiple deformities, high deviations etc. were included in the study. The OTS was used in 30 patients and the ENS was performed in 30 patients. The Nasal Obstruction Symptom Evaluation (NOSE) scale was administered preoperatively and at first month following surgery. Patients were also evaluated for pain postoperatively with Visual Analog Scale (VAS). Results: The mean NOSE score was decreased 62.5---11.0 in the OTS group and 61.3---21.33 in the ENS group. Improvement of the symptoms following the two surgical techniques is similar and no statistically significant difference was found between both techniques. Also there was no statistically significant difference in postoperative pain between the OTS and ENS groups evaluated by VAS. Conclusion: ENS is as successful as the OTS in management difficult septal deviation cases. In patients with severe septal deformities type of the surgical technique should be selected according to the surgeon's experience and the patient's preference.

A new graft material for myringoplasty: bacterial cellulose

European Archives of Oto-Rhino-Laryngology, 2016

Midface Osseous Dimensions are not Affected by Uncorrected Nasal Septal Deviation

by Ismail Serifoglu and Duygu Altuntas

Archives of Otolaryngology & Rhinology, 2015

Recovery time for inflamed middle ear mucosa in chronic otitis media

Acta Oto-Laryngologica, 2015

The present study shows that 2-3 weeks after medical treatment the status of middle ear mucosa in... more The present study shows that 2-3 weeks after medical treatment the status of middle ear mucosa in draining ears is similar to that of dry ears for at least 3 months. To measure the time required for an inflamed middle ear mucosa to return into optimal state after appropriate medical treatment in chronic suppurative otitis media (CSOM). To assess optimal timing for elective surgical treatment of draining ears in uncomplicated CSOM. In this prospective study, the Eustachian tube (ET) mucociliary clearance time (MCT) was used as the method to demonstrate the status of middle ear mucosa. In group 1 (28 patients) ET-MCT was measured in ears that were free of drainage for at least 3 months. In Group 2 (21 patients), ET-MCT was measured in draining ears, who responded to 10-14 days medical treatment, at presentation, after 10 days and 1 month. The ET-MCT was 8.63 ± 1.32 min in group 1 and 28.96 ± 8.19 min in group 2 at presentation; and the difference was statistically significant (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.001). The ET-MCT was 14.76 ± 5.11 min after 10 days and 9.31 ± 2.33 min after 1 month in group 2. The ET-MCT was indifferent between groups 1 and 2 after 1 month (p = 0.235).

Audiometric correlations with pathologies of ossicular chain in 159 ears with chronic otitis media

Clinical Otolaryngology, 2016

Hearing loss in chronic suppurative otitis media may result from tympanic membrane perforation an... more Hearing loss in chronic suppurative otitis media may result from tympanic membrane perforation and/or a pathology of the ossicular chain including discontinuity or immobility. We analysed preoperative audiogram and intraoperative findings in ears with chronic suppurative otitis media to investigate predictive value of audiogram in diagnosis of ossicular chain pathologies. The air-bone gaps at 500, 1000 and 2000 Hz were significantly higher in ears with immobile vs. mobile ossicular chain and the air-bone gap at 4000 Hz was not different. The air-bone gaps at 500, 1000, 2000 or 4000 Hz were significantly greater in ears with ossicular chain discontinuity than in ears with intact ossicular chain. Ears with intact ossicular chain, independent from being mobile or immobile, shows best hearing (least air-bone gap) at 2000 Hz compared to other frequencies while the ears with ossicular chain discontinuity causes greater air-bone gap at all frequencies including 2000 Hz. This article is protected by copyright. All rights reserved.

Role of Chlamydia pneumoniae and Helicobacteria pylori in the development of tympanosclerosis

European Archives of Oto-Rhino-Laryngology, 2015

The etiology of tympanosclerosis (TS) is not known, but TS commonly develops secondary to acute a... more The etiology of tympanosclerosis (TS) is not known, but TS commonly develops secondary to acute and chronic otitis media (COM). Since calcification process in TS resembles that of atherosclerosis (AS), pathogens that are related to pathogenesis of AS may be involved in development of TS. This prospective and controlled study, performed at a tertiary referral center, investigated a possible relationship between the presence of Chlamydia (C.) pneumoniae and Helicobacter (H.) pylori and the development of a tympanosclerotic plaque. The presence of C. pneumoniae was examined in the surgical specimens of 62 patients (29 females and 33 males; age range 10-70 years, mean age 30.8 ± 13.3 years), including 30 patients with TS, 14 patients with cholesteatoma, and 18 patients with chronic suppurative otitis media (CSOM). The presence of H. pylori was examined in the surgical specimens of 88 patients (41 females and 47 males; age range 6-70 years, mean age 32.5 ± 14.8 years), including 35 patients with TS, 22 patients with cholesteatoma, 20 patients with CSOM, and 11 patients with otosclerosis. Tympanosclerotic plaques and control specimens from the cholesteatoma, polypoid mucosa, or mucosal portion of the perforations and stapes supra structure were examined for the presence of H. pylori and/or C. pneumoniae using real-time polymerase chain reaction analysis. The analysis demonstrated that specimens from the tympanosclerotic plaques and the other types of COM were all negative for C. pneumoniae and H. pylori. An association between C. pneumoniae or H. pylori infection and the development of TS or other types of COM could not be established.

[Peripheral ossifying fibroma of maxilla]

Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat

Peripheral ossifying fibromas are rare pathologies characterized by the replacement of bone to fi... more Peripheral ossifying fibromas are rare pathologies characterized by the replacement of bone to fibrous tissue. In this article, we report a 64-year-old female case admitted to our clinic with a mass in the oral cavity for 10 years. On physical examination, a 5x4 cm, well-defined, pedunculated mass was detected in the anterior arch of the right maxilla. Based on the clinical, radiographic and histopathological findings, the mass was diagnosed as an ossifying fibroma.

Risk factors for otitis media effusion in children who have adenoid hypertrophia

International Journal of Pediatric Otorhinolaryngology, 2015

Objective: Many studies have shown that children with adenoid hypertrophy (AH) are more likely to... more Objective: Many studies have shown that children with adenoid hypertrophy (AH) are more likely to have chronic otitis media with effusion (COME). However, not every child with AH has COME. In this study, we investigated the socio-demographic risk factors of children who underwent surgery for AH, including a subgroup with COME. Our aim was to identify the factors involved in the development of COME. The study population consisted of 170 pediatric patients (118 males, 52 females) who underwent adenoidectomy between 2005 and 2008. The patients were divided into two groups, those with AH alone and those with AH and COME (AH+COME). Major factors such as age, gender, breast-milk feeding, bottle-feeding, tobacco smoke exposure, familial predisposition, allergies, congenital diseases, and school attendance were compared between the two groups. Results: AH alone was detected in 102 of the patients, 68% of whom were male, and AH+COME in the remaining 68, of whom 72% were male. The mean age was 6.5 years in the AH group and 5.3 years in the AH+COME group. There were no significant differences between the two groups with respect to breast-feeding, bottle-feeding, familial predisposition, tobacco exposure, and allergies. However, the relationships between COME and male sex, congenital diseases, and school attendance were significant. Conclusions: COME is seen in young children with AH. Among the socio-demographic features examined in this study, only male sex, congenital diseases, and school attendance were statistically significant risk factors for COME development.

Effects of Duct Shape on a Ducted Propeller Performance

51st AIAA Aerospace Sciences Meeting including the New Horizons Forum and Aerospace Exposition, 2013

Performance characteristics and velocity field of a ducted propeller in hover and axial flight co... more Performance characteristics and velocity field of a ducted propeller in hover and axial flight conditions are investigated experimentally. Five different circular duct shapes has been tested. Effect of duct geometry is studied by means of measurements at various flow conditions. Velocity field upstream and downstream of the propeller, axial force acting on each component of the propulsive system, rotor speed and torque are measured. Pressure distribution on duct inner surface is also investigated. Experimental results obtained for open and ducted propeller are compared.

Effects of polymer-based, silver nanoparticle-coated silicone splints on the nasal mucosa of rats

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, Jan 18, 2016

Infection is a serious complication after nasal packing that otolaryngologists seek to avoid. The... more Infection is a serious complication after nasal packing that otolaryngologists seek to avoid. The aim of this study is to investigate the use of silver (Ag) nanoparticle, which serves as antimicrobial agents, with nasal tampons. The study design is an experimental animal model and the setting is tertiary referral center. Twenty-four rats were randomized into the following four groups: (1) control group (n = 6); (2) silicone nasal splint (SNS) group (n = 6); (3) polypropylene-grafted polyethylene glycol (PP-g-PEG) amphiphilic graft copolymer-coated SNS group (n = 6); and (4) Ag nanoparticle-embedded PP-g-PEG (Ag-PP-g-PEG) amphiphilic graft copolymer-coated SNS group (n = 6). These tampons were applied to rats for 48 h, after which they were removed in a sterile manner, and the rats were sacrificed. The nasal septa of the rats were excised, and assessments of tissue changes in the nasal mucosa were compared among the groups. The removed tampons were microbiologically examined, a...

The effects of surgery type and different ossiculoplasty materials on the hearing results in cholesteatoma surgery

European Archives of Oto-Rhino-Laryngology, 2016

To investigate the effects of surgery type [intact canal wall (ICW) or canal wall down (CWD) mast... more To investigate the effects of surgery type [intact canal wall (ICW) or canal wall down (CWD) mastoidectomy] and different ossiculoplasty materials on hearing outcome in single-staged cholesteatoma surgery. A retrospective case-control study. A total of 116 cases (97 adults, 29 children) underwent surgery, including ossiculoplasty, between 2012 and 2015 for cholesteatoma. Patients who had undergone surgery for the first time, and whose grafts were successful, were included in the study. Patients with adhesive otitis media, unsuccessful grafts, revision and recurrent cases, radical mastoidectomy, and craniofacial anomalies were excluded. Audiogram examinations of the enrolled patients were performed 3-6 months after surgery, and the audiometric results were analyzed according to the criteria of the American Academy of Otolaryngology, Head and Neck Surgery. All ossiculoplasties were performed during the first operation. The preoperative average air-bone gap (ABG) of the patients was decreased from 31.37 ± 10.1 to 27.42 ± 10.4 dB; this decrease was found to be highly significant (p = 0.0001). Concerning the ICW

Reply to the letter to the editor ''in response to: a better design is needed for clinical studies of chronic tympanic membrane perforations using biological materials'' 10.1007/s00405-016-4019-0

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, Nov 1, 2016

Design of TENS Electrodes Using Diff erent Production Techniques

Tekstilec, 2016

Transcutaneous electrical nerve stimulation (TENS) treatment has been widely used in physical the... more Transcutaneous electrical nerve stimulation (TENS) treatment has been widely used in physical therapy to relieve diff erent types of pain. The TENS therapy is a non-invasive method applied with general types of electrodes, i.e. carbon and self-adhesive hydrogel electrodes. These electrodes are reusable, which might cause hygiene problems. In this study, two diff erent types of textile TENS electrodes were designed and produced with the sewing and embroidering technique using conductive yarn. Afterwards, the resistance values of produced electrodes were measured and compared to conventional carbon and self-adhesive hydrogel electrodes. Furthermore, the designed electrodes were connected to a commercially available TENS device and current transmission from the electrodes was tested on subjects.

Pretreatment Neutrophil-Lymphocyte Ratio in Salivary Gland Tumors Is Associated with Malignancy

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, Dec 19, 2016

To assess pretreatment levels in the counts and percentages of leukocytes and the neutrophil-lymp... more To assess pretreatment levels in the counts and percentages of leukocytes and the neutrophil-lymphocyte ratio (NLR) in benign and malignant salivary gland tumors (SGTs) while investigating whether NLR is an inflammatory marker for distinguishing low- from high-grade parotid gland tumors. Case series with chart review. Tertiary referral center. This study was performed on 182 patients with SGTs (age range: 16-87 years; 93 male and 89 female) who were treated between January 2010 and May 2015. Pretreatment counts and percentages of leukocytes and NLR were measured preoperatively in benign and malignant tumors. Mean neutrophil percentage (63.50% ± 12.11% vs 58.76% ± 8.20%, P = .008) and NLR (3.29 ± 3.13 vs 2.13 ± 1.26, P = .008) were significantly higher in patients with malignant SGTs than in patients with benign SGTs. Mean lymphocyte count (2.42 ± 0.72 10(3)/mm(3) vs 1.97 ± 0.87 10(3)/mm(3), P < .001) and percentage (30.67% ± 7.68% vs 26.86% ± 10.15%, P = .011) were lower in patie...

Design of TENS electrodes using conductive yarn

International Journal of Clothing Science and Technology, 2016

Purpose – The purpose of this paper is to develop textile-based transcutaneous electrical nerve s... more Purpose – The purpose of this paper is to develop textile-based transcutaneous electrical nerve stimulation (TENS) electrodes using conductive yarn to bring a solution to uncomfortable feelings and hygiene problems of conventional conductive hydrogel electrodes. It proposes washing process, resistance measurements and subjective tests to evaluate the performance of the developed textile-based electrode. Design/methodology/approach – In this study, six different textile electrode pairs were designed and produced with different patterns. Designed electrodes were washed for ten times. In order to evaluate the effect of pattern differences and washing process on electrode performances, two different tests were realized before and after washing. The first of these tests is resistance measurement with a multimeter, and the second one is subjective test carried out on subjects. Findings – The results obtained from resistance measurements indicated that the pattern differences cause resista...

Difficult septal deviation cases: open or closed technique?

Brazilian Journal of Otorhinolaryngology, 2017

The aim of this study is to compare the functional aspects of open technique (OTS) and endonasal ... more The aim of this study is to compare the functional aspects of open technique (OTS) and endonasal septoplasty (ENS) in ''difficult septal deviation cases''. Methods: 60 patients with severe nasal obstruction from S-shaped deformities, multiple deformities, high deviations etc. were included in the study. The OTS was used in 30 patients and the ENS was performed in 30 patients. The Nasal Obstruction Symptom Evaluation (NOSE) scale was administered preoperatively and at first month following surgery. Patients were also evaluated for pain postoperatively with Visual Analog Scale (VAS). Results: The mean NOSE score was decreased 62.5---11.0 in the OTS group and 61.3---21.33 in the ENS group. Improvement of the symptoms following the two surgical techniques is similar and no statistically significant difference was found between both techniques. Also there was no statistically significant difference in postoperative pain between the OTS and ENS groups evaluated by VAS. Conclusion: ENS is as successful as the OTS in management difficult septal deviation cases. In patients with severe septal deformities type of the surgical technique should be selected according to the surgeon's experience and the patient's preference.

A new graft material for myringoplasty: bacterial cellulose

European Archives of Oto-Rhino-Laryngology, 2016

Midface Osseous Dimensions are not Affected by Uncorrected Nasal Septal Deviation

by Ismail Serifoglu and Duygu Altuntas

Archives of Otolaryngology & Rhinology, 2015

Recovery time for inflamed middle ear mucosa in chronic otitis media

Acta Oto-Laryngologica, 2015

The present study shows that 2-3 weeks after medical treatment the status of middle ear mucosa in... more The present study shows that 2-3 weeks after medical treatment the status of middle ear mucosa in draining ears is similar to that of dry ears for at least 3 months. To measure the time required for an inflamed middle ear mucosa to return into optimal state after appropriate medical treatment in chronic suppurative otitis media (CSOM). To assess optimal timing for elective surgical treatment of draining ears in uncomplicated CSOM. In this prospective study, the Eustachian tube (ET) mucociliary clearance time (MCT) was used as the method to demonstrate the status of middle ear mucosa. In group 1 (28 patients) ET-MCT was measured in ears that were free of drainage for at least 3 months. In Group 2 (21 patients), ET-MCT was measured in draining ears, who responded to 10-14 days medical treatment, at presentation, after 10 days and 1 month. The ET-MCT was 8.63 ± 1.32 min in group 1 and 28.96 ± 8.19 min in group 2 at presentation; and the difference was statistically significant (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.001). The ET-MCT was 14.76 ± 5.11 min after 10 days and 9.31 ± 2.33 min after 1 month in group 2. The ET-MCT was indifferent between groups 1 and 2 after 1 month (p = 0.235).

Audiometric correlations with pathologies of ossicular chain in 159 ears with chronic otitis media

Clinical Otolaryngology, 2016

Hearing loss in chronic suppurative otitis media may result from tympanic membrane perforation an... more Hearing loss in chronic suppurative otitis media may result from tympanic membrane perforation and/or a pathology of the ossicular chain including discontinuity or immobility. We analysed preoperative audiogram and intraoperative findings in ears with chronic suppurative otitis media to investigate predictive value of audiogram in diagnosis of ossicular chain pathologies. The air-bone gaps at 500, 1000 and 2000 Hz were significantly higher in ears with immobile vs. mobile ossicular chain and the air-bone gap at 4000 Hz was not different. The air-bone gaps at 500, 1000, 2000 or 4000 Hz were significantly greater in ears with ossicular chain discontinuity than in ears with intact ossicular chain. Ears with intact ossicular chain, independent from being mobile or immobile, shows best hearing (least air-bone gap) at 2000 Hz compared to other frequencies while the ears with ossicular chain discontinuity causes greater air-bone gap at all frequencies including 2000 Hz. This article is protected by copyright. All rights reserved.

Role of Chlamydia pneumoniae and Helicobacteria pylori in the development of tympanosclerosis

European Archives of Oto-Rhino-Laryngology, 2015

The etiology of tympanosclerosis (TS) is not known, but TS commonly develops secondary to acute a... more The etiology of tympanosclerosis (TS) is not known, but TS commonly develops secondary to acute and chronic otitis media (COM). Since calcification process in TS resembles that of atherosclerosis (AS), pathogens that are related to pathogenesis of AS may be involved in development of TS. This prospective and controlled study, performed at a tertiary referral center, investigated a possible relationship between the presence of Chlamydia (C.) pneumoniae and Helicobacter (H.) pylori and the development of a tympanosclerotic plaque. The presence of C. pneumoniae was examined in the surgical specimens of 62 patients (29 females and 33 males; age range 10-70 years, mean age 30.8 ± 13.3 years), including 30 patients with TS, 14 patients with cholesteatoma, and 18 patients with chronic suppurative otitis media (CSOM). The presence of H. pylori was examined in the surgical specimens of 88 patients (41 females and 47 males; age range 6-70 years, mean age 32.5 ± 14.8 years), including 35 patients with TS, 22 patients with cholesteatoma, 20 patients with CSOM, and 11 patients with otosclerosis. Tympanosclerotic plaques and control specimens from the cholesteatoma, polypoid mucosa, or mucosal portion of the perforations and stapes supra structure were examined for the presence of H. pylori and/or C. pneumoniae using real-time polymerase chain reaction analysis. The analysis demonstrated that specimens from the tympanosclerotic plaques and the other types of COM were all negative for C. pneumoniae and H. pylori. An association between C. pneumoniae or H. pylori infection and the development of TS or other types of COM could not be established.

[Peripheral ossifying fibroma of maxilla]

Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat

Peripheral ossifying fibromas are rare pathologies characterized by the replacement of bone to fi... more Peripheral ossifying fibromas are rare pathologies characterized by the replacement of bone to fibrous tissue. In this article, we report a 64-year-old female case admitted to our clinic with a mass in the oral cavity for 10 years. On physical examination, a 5x4 cm, well-defined, pedunculated mass was detected in the anterior arch of the right maxilla. Based on the clinical, radiographic and histopathological findings, the mass was diagnosed as an ossifying fibroma.

Risk factors for otitis media effusion in children who have adenoid hypertrophia

International Journal of Pediatric Otorhinolaryngology, 2015

Objective: Many studies have shown that children with adenoid hypertrophy (AH) are more likely to... more Objective: Many studies have shown that children with adenoid hypertrophy (AH) are more likely to have chronic otitis media with effusion (COME). However, not every child with AH has COME. In this study, we investigated the socio-demographic risk factors of children who underwent surgery for AH, including a subgroup with COME. Our aim was to identify the factors involved in the development of COME. The study population consisted of 170 pediatric patients (118 males, 52 females) who underwent adenoidectomy between 2005 and 2008. The patients were divided into two groups, those with AH alone and those with AH and COME (AH+COME). Major factors such as age, gender, breast-milk feeding, bottle-feeding, tobacco smoke exposure, familial predisposition, allergies, congenital diseases, and school attendance were compared between the two groups. Results: AH alone was detected in 102 of the patients, 68% of whom were male, and AH+COME in the remaining 68, of whom 72% were male. The mean age was 6.5 years in the AH group and 5.3 years in the AH+COME group. There were no significant differences between the two groups with respect to breast-feeding, bottle-feeding, familial predisposition, tobacco exposure, and allergies. However, the relationships between COME and male sex, congenital diseases, and school attendance were significant. Conclusions: COME is seen in young children with AH. Among the socio-demographic features examined in this study, only male sex, congenital diseases, and school attendance were statistically significant risk factors for COME development.

Effects of Duct Shape on a Ducted Propeller Performance

51st AIAA Aerospace Sciences Meeting including the New Horizons Forum and Aerospace Exposition, 2013

Performance characteristics and velocity field of a ducted propeller in hover and axial flight co... more Performance characteristics and velocity field of a ducted propeller in hover and axial flight conditions are investigated experimentally. Five different circular duct shapes has been tested. Effect of duct geometry is studied by means of measurements at various flow conditions. Velocity field upstream and downstream of the propeller, axial force acting on each component of the propulsive system, rotor speed and torque are measured. Pressure distribution on duct inner surface is also investigated. Experimental results obtained for open and ducted propeller are compared.