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  2. Hemodynamic instability, a life-threatening condition marked by circulatory failure, presents a significant challenge in intensive care unit (ICU) settings, often leading to poor patient outcomes. Traditional ...

    Authors: Dung-Hung Chiang, Zeyu Jiang, Cong Tian and Chien-Ying Wang
    Citation: Critical Care 2025 29:318
    Content type: Research Published on:

  4. Out-of-hospital cardiac arrest (OHCA) has poor survival rates, but extracorporeal cardiopulmonary resuscitation (ECPR) shows promise for selected patients, as a second line of therapy after failure of conventi...

    Authors: Masahiro Kashiura, Yuki Kishihara, Hiroyuki Tamura, Shunsuke Amagasa, Hideto Yasuda and Takashi Moriya
    Citation: Critical Care 2025 29:316
    Content type: Research Published on:

  5. Millions of households have cats or dogs as pets, and infections due to bites or scratches are increasing, with the most common pathogens being Pasteurella spp., Bartonella spp., Capnocytophaga spp, and Francisel...

    Authors: Juliette Quintin, Aurélie Le Thuaut, Fabienne Plouvier, Yoann Zerbib, Michel Sirodot, Nicholas Sedillot, Kahaia de Longeaux, Anthony Le Meur, Bertrand Souweine, Jean-Pierre Quenot, Jean-Claude Lacherade, Julie Noublanche, Mickael Landais, Didier Thevenin, Saad Nseir, Thomas Lafon…
    Citation: Critical Care 2025 29:315
    Content type: Research Published on:

  7. Authors: Makoto Aoki, Toshikazu Abe, Akira Komori, Morihiro Katsura and Kazuhide Matsushima
    Citation: Critical Care 2025 29:313
    Content type: Matters Arising Published on:

    The original article was published in Critical Care 2024 28:253

    The original article was published in Critical Care 2024 28:395

    The original article was published in Critical Care 2024 28:390

  8. Pain and anxiety are frequent among critically ill patients undergoing unplanned invasive procedures, and pharmacological pain relief is not always possible. Although hypnosis is widely used in planned painful...

    Authors: Adel Maamar, Claude Faleur, Kristell Pedrono, Marie-Pierre Adeux, Magali Anne, Adeline Verdes, Pierre Fillâtre, Matthieu Debarre, Nathalie Mercier, Matthieu Revest, Nicolas Massart, Noémie Poilvet, Nicolas Terzi, Jean-Marc Tadié, Arnaud Gacouin and Bruno Laviolle
    Citation: Critical Care 2025 29:312
    Content type: Research Published on:

  10. Admissions of immunocompromised patients to intensive care units (ICUs) are on the increase. The main reason for admission is acute respiratory failure, predominantly of infectious origin. In such circumstance...

    Authors: Jérémy Contier, Laura Platon, Nacim Benchabane, Sonia Tchakerian, Fanchon Herman, Caroline Mollevi, Patrice Ceballos, Sylvain Godreuil and Kada Klouche
    Citation: Critical Care 2025 29:310
    Content type: Research Published on:

  11. Septic shock is a critical condition associated with high mortality and resource utilization. Although improvements in early recognition and management of sepsis have been reported globally, the trends in clin...

    Authors: Taro Imaeda, Takehiko Oami, Tatsuro Yokoyama, Satoshi Nakagawa, Hiroshi Ogura, Nobuaki Shime, Yutaka Umemura, Asako Matsushima, Kiyohide Fushimi and Taka-aki Nakada
    Citation: Critical Care 2025 29:309
    Content type: Research Published on:

  12. Inadequate spinal perfusion in acute spinal cord injury (SCI) can exacerbate secondary injury. While current guidelines recommend maintaining mean arterial pressure (MAP) ≥ 75-80mmHg post-injury, no quantitati...

    Authors: Azasma Tanvir, Abramo Aziz Rizk, Wendy Wang, Hamed Alsagga, Husain Shakil, Ha Le, Prosanta Mondal, Frederick A. Zeiler and Tumul Chowdhury
    Citation: Critical Care 2025 29:308
    Content type: Review Published on:

  17. Immediate initiation of extracorporeal membrane oxygenation (ECMO) has not demonstrated benefit in individuals diagnosed with cardiogenic shock based on the presence of hypotension. The relationship between ot...

    Authors: Petr Ostadal, Dagmar Vondrakova, Richard Rokyta, Jiri Karasek, Andreas Kruger, Marek Janotka, Jan Naar, Jana Smalcova, Marketa Hubatova, Milan Hromadka, Stefan Volovar, Miroslava Seyfrydova, Ales Linhart and Jan Belohlavek
    Citation: Critical Care 2025 29:303
    Content type: Research Published on:

  18. The current Surviving Sepsis Campaign (SSC) guidelines provide recommendations on timing of administering antibiotics in sepsis patients based on probability of sepsis and presence of shock. However, there hav...

    Authors: Ben J. Gross, Allison Donahue, James S. Ford, Xiaolei Lu, Aaron Boussina, Atul Malhotra, Kai Zheng, Shamim Nemati and Gabriel Wardi
    Citation: Critical Care 2025 29:302
    Content type: Research Published on:

  19. Accurate microbiological documentation seems central for managing severe pneumonia. While the FilmArray® Pneumonia + panel (FA-PP) offers rapid pathogen identification, its effectiveness during antibiotic treatme...

    Authors: Julien Dessajan, Michaël Thy, Marc Doman, Jules Stern, Antoine Gallet, Gaëlle Fouque, Samuel Chosidow, Stéphane Ruckly, Signara Gueye, Fariza Lamara, Mariem Dlela, Hermann Do Rego, Michaël Ejzenberg, Luc Haudebourg, Julien Le Marec, Cyril Potier…
    Citation: Critical Care 2025 29:301
    Content type: Research Published on:

  20. Adiponectin, a key adipokine primarily secreted by adipocytes, plays crucial roles in metabolic homeostasis and inflammation, exhibiting anti-diabetic, anti-atherogenic, and anti-inflammatory properties. Its v...

    Authors: Stefano Gianoli, Justin Tang, Kirsten C. Odegard, Koichi Yuki and Sophia Koutsogiannaki
    Citation: Critical Care 2025 29:300
    Content type: Review Published on:

  21. To evaluate the interchangeability of cardiac output (CO) monitoring devices compared to reference methods in adult ICU patients with septic shock, we systematically searched electronic databases through Janua...

    Authors: Raquel Lamarche-Fontaneto, Lee Oud, Kayln D. Howell, Simran A. Ganeriwal, Gaurav U. Manek, Mary C. Schleicher, Jihad Mallat, Maurizio Cecconi, Abhijit Duggal and Matthew T. Siuba
    Citation: Critical Care 2025 29:299
    Content type: Review Published on:

  22. Pediatric acute respiratory distress syndrome (PARDS) causes significant morbidity and mortality, especially in resource-limited settings. This study assessed national hospital and PICU admission rates, region...

    Authors: Rattapon Uppala, Phanthila Sitthikarnkha, Leelawadee Techasatian, Suchaorn Saengnipanthkul, Pope Kosalaraksa, Kaewjai Thepsuthammarat and Sirapoom Niamsanit
    Citation: Critical Care 2025 29:298
    Content type: Research Published on:

  23. Sodium-glucose cotransport-2 inhibitors (SGLT2i) have established benefits in diabetes mellitus, heart failure, and chronic kidney disease, but their physiological effects during critical illness remain unclea...

    Authors: Fernando G. Zampieri, Luciano C. P. Azevedo, Ary Serpa Neto, Álvaro Rea-Neto, Paula G. David-João, Cristina P. Amendola, Amanda C. Kozesinski-Nakatani, Thiago C. Filiponi, Guacyra M. B. Almeida, Ricardo R. Bergo, Rodrigo C. Figueiredo, Clewer J. Schuler, Glauco A. Westphal, Rodrigo S. Biondi, Adriano J. Pereira, Thiago D. Correa…
    Citation: Critical Care 2025 29:297
    Content type: Research Published on:

  25. Patient-ventilator asynchrony (PVA) is a common and harmful complication during mechanical ventilation, often requiring labor-intensive manual assessment. Machine learning (ML) offers a promising approach for ...

    Authors: Guanxu Jiang, Jiawei Ma, Hao Xu, Zigang Zhu, Yi Xie, Shenhui Ji, Tao Yan and Liang Luo
    Citation: Critical Care 2025 29:295
    Content type: Research Published on:

  28. Guidelines recommend immediate endotracheal intubation for patients with a GCS score ≤ 8. However, the impact of immediate airway intubation on patient outcomes remains uncertain. This study aimed to investiga...

    Authors: Keita Shibahashi, Ken Inoue, Taichi Kato and Kazuhiro Sugiyama
    Citation: Critical Care 2025 29:292
    Content type: Research Published on:

  30. Artificial Intelligence (AI) is rapidly transforming the landscape of critical care, offering opportunities for enhanced diagnostic precision and personalized patient management. However, its integration into ...

    Authors: Maurizio Cecconi, Massimiliano Greco, Benjamin Shickel, Derek C. Angus, Heatherlee Bailey, Elena Bignami, Thierry Calandra, Leo Anthony Celi, Sharon Einav, Paul Elbers, Ari Ercole, Hernando Gómez, Michelle Ng Gong, Matthieu Komorowski, Vincent Liu, Soojin Park…
    Citation: Critical Care 2025 29:290
    Content type: Consensus Article Published on:

  31. The aim of this study was to evaluate the effects of three different PEEP titration strategies in ARDS patients, one based on driving pressure and two based on oxygenation (one PEEP level according to the high...

    Authors: Silvia Coppola, Giulia Catozzi, Tommaso Pozzi, Alessandro Monte, Geraldina Besana, Laura Depedri and Davide Chiumello
    Citation: Critical Care 2025 29:289
    Content type: Research Published on:

  33. There is no current consensus on the appropriate timing for discontinuing continuous renal replacement therapy (CRRT). We aimed to review the current clinical evidence associated with the successful liberation...

    Authors: Rupesh Raina, Kianoush Kashani, Sidharth Kumar Sethi, Quen Mok, Aadil Kakajiwala, Samir M. Parikh, Kush Doshi, Jieji Hu, Khalid Alhasan, Marcelo de Sousa Tavares, Hui Kim Yap, Arwa Nada, Timothy Bunchman, Javier A. Neyra, Samuel A. Silver and Ashita Tolwani
    Citation: Critical Care 2025 29:287
    Content type: Consensus Article Published on:

  34. Self-extubation is a common complication in intubated patients in the intensive care unit (ICU) and is associated with a high rate of reintubation. This study aimed to identify predictors of reintubation follo...

    Authors: Léa Trenchat, Louis-Marie Galerneau, Stéphane Ruckly, Florian Sigaud, Nicolas Terzi, Maité Garrouste, Johanna Oziel, Vivien Hong Tuan Ha, Marc Gainnier, Shidasp Siami, Anaïs Dartevel, Claire Dupuis, Jean-Marie Forel, Julien Dessajan, Christophe Adrie, Dany Goldgran-Toledano…
    Citation: Critical Care 2025 29:286
    Content type: Research Published on:

  35. This network meta-analysis (NMA) compared the efficacy of various respiratory training methods in improving respiratory function in patients with spinal cord injury (SCI).

    Authors: Jun Chen, Tianyu Chen, Xia Wang, Xin Tang, Shunyan Yang, Kaiyue Lyu, Fei Li, Jishu Xian, Binbin Tan and Yujie Chen
    Citation: Critical Care 2025 29:285
    Content type: Research Published on:

  38. Acute Respiratory Distress Syndrome (ARDS) is a life-threatening condition characterized by acute onset of respiratory failure, which presents significant challenges in diagnosis and management. Its heterogene...

    Authors: Denise Battaglini, Marcus J. Schultz, Gustavo A. Cortes Puentes, John J. Marini and Patricia R. M. Rocco
    Citation: Critical Care 2025 29:282
    Content type: Review Published on:

  39. Candidemia is a life-threatening fungal infection in intensive care unit (ICU) patients that can be complicated by secondary localization (SL). However, the prevalence, risk-factors, and outcomes of patients w...

    Authors: Florian Reizine, Juliette Henry, Luc Desmedt, Christophe Camus, Valentin Coirier, François Arrive, Estelle Burban, Gabriel Eustache, Tony Belleville, Antoine Marc, Jolan Malherbe, Pierre Bouju, Paul Jaubert, Olivier Lesieur, Maxime Leclerc, Pierre Fillâtre…
    Citation: Critical Care 2025 29:281
    Content type: Research Published on:

  41. Authors: Felipe Muñoz, Cecilia González, Ricardo Castro, Philippe Rola, Glenn Hernández and Eduardo Kattan
    Citation: Critical Care 2025 29:279
    Content type: Matters Arising Published on:

    The original article was published in Critical Care 2024 28:52

    The original article was published in Critical Care 2025 29:262

  42. After the strict visitation restrictions during the COVID-19 pandemic, the value of family presence has been re-emphasized as an essential part of patient- and family-centred care in the intensive care unit (I...

    Authors: Kasumi Shirasaki, Kaori Shimazu, Shinsuke Hashiuchi, Toru Hifumi, Masaki Okajima and Norio Otani
    Citation: Critical Care 2025 29:278
    Content type: Research Published on:

  45.  Ventilator-associated pneumonia (VAP) is a common complication in patients under invasive mechanical ventilation (IMV), yet its underlying mechanisms remain poorly understood. This study investigated the lung...

    Authors: Ingrid G. Bustos, Cristian C. Serrano-Mayorga, José L. Guerrero, Jennifer M. Baker, Christopher Brown, Nicole Falkowski, Piyush Ranjan, Alejandro Acosta-Gonzalez, Lina M. Mendez, Acenet Garcia-Cordoba, Adriana Echeverry-Gutierrez, Denis A. Bojaca, Marcela Chisica-Mahecha, Nicol Guarin-Tequia, Liliana Romero-Romero, Norberto Gonzalez-Juarbe…
    Citation: Critical Care 2025 29:275
    Content type: Research Published on:

  46. Assessing neurological outcome after cardiac arrest (CA) remains challenging. We aim to evaluate the prognostic value of brainstem auditory evoked potentials (BAEPs) and middle latency auditory evoked potentia...

    Authors: Camélia Banana, Estelle Pruvost-Robieux, Wulfran Bougouin, Julie Lévi-Strauss, Camille Legouy, Martine Gavaret, Tarek Sharshar, Alain Cariou and Sarah Benghanem
    Citation: Critical Care 2025 29:274
    Content type: Research Published on:

  47. Vasopressin is currently suggested as a second-line vasopressor in patients with septic shock and persistent arterial hypotension. This survey aimed to assess the current use of vasopressin and terlipressin in...

    Authors: Mathieu Jozwiak, Vladimir L. Cousin, Daniel De Backer, Manu L. N. G. Malbrain, Xavier Monnet, Antonio Messina and Michelle S. Chew
    Citation: Critical Care 2025 29:273
    Content type: Research Published on:

  48. Mechanical ventilation is essential for treating respiratory failure. However, ventilator over-assistance can lead to ventilator-induced diaphragm dysfunction (VIDD), and insufficient assistance can necessitat...

    Authors: Yinxia Lv, Meiling Dong, Haisong Song, Jinglei Liu, Zhiwen Huang, Zhong Ni, Zhen Wang, Xiaorong Jing, Xiaoyong Zhou, Yongfang Zhou, Yan Kang and Bo Wang
    Citation: Critical Care 2025 29:272
    Content type: Research Published on:
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  • ISSN: 1364-8535 (electronic)

Critical Care

ISSN: 1364-8535