DAPK2

DAPK2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1WMK, 1WRZ, 1Z9X, 1ZUZ, 1ZWS, 2A27, 2A2A, 2CKE
Dynodwyr
Cyfenwau	DAPK2, DRP-1, DRP1, death-associated protein kinase 2, death associated protein kinase 2
Dynodwyr allanol	OMIM: 616567 HomoloGene: 74940 GeneCards: DAPK2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • protein kinase activity • calmodulin binding • kinase activity • protein serine/threonine kinase activity • GO:0001948, GO:0016582 protein binding • identical protein binding • ATP binding Cydrannau o'r gell • cytoplasm • autophagosome lumen • GO:0016023 cytoplasmic vesicle • Golgi apparatus • intracellular membrane-bounded organelle • cnewyllyn cell Prosesau biolegol • regulation of apoptotic process • GO:0007243 intracellular signal transduction • regulation of intrinsic apoptotic signaling pathway • phosphorylation • protein phosphorylation • positive regulation of eosinophil chemotaxis • regulation of autophagy • anoikis • positive regulation of neutrophil chemotaxis • protein autophosphorylation • neutrophil migration • GO:0097285 apoptotic process • GO:0035404 peptidyl-serine phosphorylation • peptidyl-threonine phosphorylation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23604	n/a
Ensembl	ENSG00000035664	n/a
UniProt	Q9UIK4	n/a
RefSeq (mRNA)	NM_014326 NM_001363730 NM_001384997 NM_001384998 NM_001384999 NM_001385000	n/a
RefSeq (protein)	NP_055141 NP_001350659	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DAPK2 yw DAPK2 a elwir hefyd yn Death associated protein kinase 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 15, band 15q22.31.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DAPK2.

• DRP1
• DRP-1

Llyfryddiaeth

• "The death-associated protein kinase 2 is up-regulated during normal myeloid differentiation and enhances neutrophil maturation in myeloid leukemic cells. ". J Leukoc Biol. 2007. PMID 17347302.
• "DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death. ". J Cell Biol. 2002. PMID 11980920.
• "Identification of Novel Death-Associated Protein Kinase 2 Interaction Partners by Proteomic Screening Coupled with Bimolecular Fluorescence Complementation. ". Mol Cell Biol. 2016. PMID 26483415.
• "DAPK2 regulates oxidative stress in cancer cells by preserving mitochondrial function. ". Cell Death Dis. 2015. PMID 25741596.
• "DAPK2 is a novel regulator of mTORC1 activity and autophagy.". Cell Death Differ. 2015. PMID 25361081.