Papers by Pallavi Sharma
International Article History: Received 20th February, 2024 Received in revised form 25th March, 2024 Accepted 14th April, 2024 Published online 23rd May, 2024 Citation: Pallavi Sharma and Tulika Mishra. 2024. Current Research, 16, (05), 28279-28282. Key words: In vitro Regeneration, Nodal ..., 2024
Gloriosa superba since time immemorial. The current rare state of this plant is the result of ove... more Gloriosa superba since time immemorial. The current rare state of this plant is the result of over medical uses. To address embryogenesis techniques needed to be standardized. In the present study, we tried to develop a standard protocol for superba explants. The combination of MS+1.5 mg/l BAP+0.5 mg/l NAA produced the most number of shoots (7±0.18), demonstrating the best shoot induction. The number of shoots per culture increased by adding 1 increased by adding 100 mg/l of urea to the media. Shoots cultivated on half supplemented with 1.0 mg/l IBA + 0.5 mg/l NAA showed the best rooting. The medic conservation components of satisfy future economic demands.
International Journal of Development Research (ISSN: 2230-9926), 2024
Colchicine is a phytochemical extracted commercially from two plants of the Colchicaceae family, ... more Colchicine is a phytochemical extracted commercially from two plants of the Colchicaceae family, Gloriosa superba (flame lily) and Colchicum autumnale (autumn crocus). One of the seven upavishas (semi-poisonous drugs) in Indian medicine, colchicine is claimed to treat a number of illnesses but can be lethal if administered improperly. Colchicine dosages greater than 10 mg in humans are always fatal within three days. Due to colchicine's potent anti-inflammatory properties, it can cure many cardiovascular conditions, including coronary artery disease, atherosclerosis, recurring pericarditis, vascular restenosis, heart failure and myocardial infarction. Colchicine has lately demonstrated therapeutic effectiveness in reducing COVID-19 cardiovascular complications. The research on colchicine's anti-inflammatory mechanisms is gaining popularity. The ability of colchicine to inhibit microtubule formation is mainly responsible for its anti-inflammatory effects. Colchicine blocks the following cellular processes: platelet stimulation, macrophage chemotaxis, migration and adhesion, smooth muscle cell growth and migration, and endothelial dysfunction and inflammation. Colchicine suppresses NF-κB signaling, the release of proinflammatory cytokines, and the activation of the NLRP3 inflammasome at the molecular level. In the present review, we are covering the reported mechanism of colchicine used as a drug in various diseases.
European Journal of Biomedical AND Pharmaceutical sciences , 2022
Gloriosa superba (Flame lily) is a creeper plant belonging to the family Colchicaceae. This plant... more Gloriosa superba (Flame lily) is a creeper plant belonging to the family Colchicaceae. This plant has been used asa remedy in classical times. In rustic regions of Asian continents, the plant has been used as ethnomedicine. It has antimicrobial, antioxidant, anti-inflammatory, anthelmintic, and anti-coagulant properties. This plant is a rich source of important phytochemicals like colchicines and colchicocides, which are very expensive, as these are used in modern medicine, this plant is also exported from India. Colchicine has the potential for treating fatal diseases like cancer and it is also used to treat the hyper-inflammatory phase in COVID-19 patients. It is also used in prevention of cardiac diseases like pericarditis. In recent years, G. superba is copiously used as a source of colchicine to treat gout because colchicine is a substitute for those who are unable to tolerate non-steroidal anti-inflammatory drugs used in gout. Literature data revealed that this species is also used to cure disorders like rheumatism, arthritis, cholera, impotence, typhus, etc. This species is on the border of extinction and is included in the „Red Data Book' by the International Union for Conservation of Nature. Current communication tried to cover an overall review of various medicinal and pharmacological aspects of G. superba.
Suraj Punj Journal for Multidisciplinary Research, 2021
Gloriosa superba (Glory lily) is an important medicinal plant but it does not propagate easily in... more Gloriosa superba (Glory lily) is an important medicinal plant but it does not propagate easily in the natural environment. Due to its high pharmaceutical demand and poor natural propagation, this plant is harvested from the wild. Consequently, it is placed in the 'Red List' of the International Union for Conservation of Nature (IUCN). The seed germination is unpredictable and takes several weeks to months to propagate and the tubers sprouts irregularly. Several studies have shown that various treatments of seed and tubers can enhance the chances of reproduction. Commercially, it is propagated through tubers because its reproduction through tubers is easier than seeds. The present communication covers the standard methods by which this rare and demanding plant can be reproduced by its tubers in easy and effective ways.
World Journal of Pharmacy and Pharmaceutical Sciences , 2020
Gloriosa superba is an excellent medicinal plant found in Africa and tropical Asian countries. Th... more Gloriosa superba is an excellent medicinal plant found in Africa and tropical Asian countries. This plant has been used as ethnomedicine in India and several parts of the world. It has shown many pharmacological activities like anti-arthritic, analgesic, uterotonic, anti-microbial, anti-inflammatory, anthelmintic, antioxidant, anti-cancerous, anti-fertility, antithrombotic, anti-diabetic, and anti-anxiety. It can also cure diseases like leprosy, piles, tumor, fistula, gout, gynecological disorders, oral diseases, vitiligo, intestinal disorders, cough, snakebite, cholera, kidney problems, typhus, and many types of endoparasitic diseases. The problems encountered during the cultivation of Gloriosa sp. (Glory lily) include, poor seed set, low tuber propagation, pests, fungal and soil-borne diseases. Due to high demand and low production, it is harvested from the wild at a high rate. This plant species has become endangered in Asian countries hence facing local extinction and it is included in 'Red Data Book' by the IUCN. Mass propagation and quality planting material can be achieved by exploring tissue culture methods to conserve this plant. The current review covers all the aspects of strategies for the conservation of Gloriosa superba.
Conference Presentations by Pallavi Sharma
Glory Lily (Gloriosa superba) is a magnificent medicinal plant found in many Asian countries. It ... more Glory Lily (Gloriosa superba) is a magnificent medicinal plant found in many Asian countries. It is potentially known to cure ulcers, gout, hemorrhoids, kidney problems, sexually transmitted diseases, etc. This plant species is a rich source of pharmacologically important bio-functional compounds like flavonoids, tannins, glycoside, luterlin, alkaloids. The seeds and tubers of G. superba contain a high quantity of Colchicine and its derivatives. Colchicine is used as a drug to treat various numbers of diseases like inflammatory diseases, heart diseases, gout, etc. Colchicine is also used to treat the hyper-inflammatory phase in COVID-19 patients. Many studies have shown that colchicine has the potential to induce apoptosis in malignant cell lines.
Uploads
Papers by Pallavi Sharma
Conference Presentations by Pallavi Sharma