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Cell cycle

Checking two steps

Nature volume 410, pages 766–767 (2001)Cite this article

When their DNA is damaged, cells temporarily stop multiplying to prevent the build-up of mutations. Two types of delay triggered by ionizing radiation appear to have common molecular starting points.

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Figure 1: Steps involved in the cell-cycle checkpoints that are induced in response to ionizing radiation.

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  1. Department of Hematology-Oncology, St Jude Children's Hospital, Memphis, 38105, Tennessee, USA

    Michael B. Kastan

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  1. Michael B. Kastan
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Correspondence to Michael B. Kastan.

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Kastan, M. Checking two steps. Nature 410, 766–767 (2001). https://doi.org/10.1038/35071218

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