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Calorie restriction falters in the long run

Genetics and healthy diets matter more for longevity.

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References

  1. Mattison, J. A. et al. Nature http://dx.doi.org/10.1038/nature11432 (2012).

  2. Colman, R. J. et al. Science 325, 201–204 (2009).

    Article  ADS  CAS  Google Scholar 

  3. Berrington de Gonzalez, A. et al. N. Engl. J. Med. 363, 2211–2219 (2010).

    Article  CAS  Google Scholar 

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Maxmen, A. Calorie restriction falters in the long run. Nature 488, 569 (2012). https://doi.org/10.1038/488569a

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