The quarterfinals were two-legged ties determined on aggregate score. The first legs was played on March 23. All return legs were played on March 30. The group winner in each tie, listed as "Team #1", hosted the second leg.
| Team #1 | Agg. | Team #2 | 1st leg | 2nd leg |
|---|---|---|---|---|
UNICS Kazan  |
169–161 |  Pepsi Caserta |
90–84 | 79-77 |
BC Budivelnyk  |
129–144 |  Cajasol |
49–67 | 80-77 |
| Asefa Estudiantes |
153–171 |  Cedevita Zagreb |
81–90 | 72-81 |
| Benetton Basket Bwin |
150–128 |  BG Göttingen |
66–66 | 84-62 |
Game 1
edit23 March 2011
18:00 |
| Cedevita Zagreb |
90–81 | Asefa Estudiantes |
| Scoring by quarter: 21–33, 26–16, 29–12, 14–20 | ||
| Pts: Rudež 21 Rebs: Petrović 8 Asts: Draper 5 |
Pts: Caner-Medley 19 Rebs: Caner-Medley 11 Asts: Granger 4 | |
Dražen Petrović Basketball Hall, Zagreb
Attendance: 5,200 Referees: Paolo Taurino (ITA), Eddie Viator (FRA), Damir Javor (SLO) |
23 March 2011
19:30 |
| BG Göttingen |
66–66 | Benetton Basket Bwin |
| Scoring by quarter: 21–15, 20–17, 9–19, 16–15 | ||
| Pts: Scott 15 Rebs: Scott 8 Asts: Meacham 3 |
Pts: Gentile 22 Rebs: Brunner 10 Asts: Marković 6 | |
23 March 2011
20:00 |
| Pepsi Caserta |
84–90 | UNICS Kazan |
| Scoring by quarter: 18–22, 26–24, 16–15, 24–29 | ||
| Pts: Williams 22 Rebs: Jones 9 Asts: Bowers 4 |
Pts: Veremeenko 30 Rebs: Veremeenko 12 Asts: Popović 6 | |
PalaMaggiò, Caserta
Attendance: 4,963 Referees: Spiros Gkontas (GRE), Robert Vyklicky (CZE), Radomir Vojinovic (MNE) |
23 March 2011
20:00 |
| Cajasol |
67–49 | BC Budivelnyk |
| Scoring by quarter: 14–16, 16–8, 13–13, 24–12 | ||
| Pts: Urtasun 15 Rebs: Kirksay 8 Asts: Urtasun, Bullock 3 |
Pts: Keys, Wilson 11 Rebs: Wilson 6 Asts: Anisimov 3 | |
Palacio Municipal San Pablo, Seville
Attendance: 7,500 Referees: Fabio Facchini (ITA), Gianluca Mattioli (ITA), Joseph Bissang (FRA) |
Game 2
edit30 March 2011
18:30 |
| UNICS Kazan |
79–77 | Pepsi Caserta |
| Scoring by quarter: 26–17, 20–18, 17–24, 16–18 | ||
| Pts: Lampe 31 Rebs: Lampe 16 Asts: Popović 6 |
Pts: Jones 23 Rebs: Jones 10 Asts: Di Bella 6 | |
Basket Hall Arena, Kazan
Attendance: 2,500 Referees: Jakub Zamojski (POL), Murat Biricik (TUR), Tomas Jasevicius (LTU) |
30 March 2011
18:30 |
| BC Budivelnyk |
80–77 | Cajasol |
| Scoring by quarter: 23–22, 17–17, 14–17, 26–21 | ||
| Pts: Ikovlev, Spencer 12 Rebs: Betts 10 Asts: Keys 4 |
Pts: Urtasun 15 Rebs: Triguero 8 Asts: Bullock, Ivanov 3 | |
Palace of Sports, Kyiv
Attendance: 3,450 Referees: Sreten Radovic (CRO), Milivoje Jovcic (SRB), Sergey Mikhaylov (RUS) |
30 March 2011
20:30 |
| Asefa Estudiantes |
72–81 | Cedevita Zagreb |
| Scoring by quarter: 25–26, 17–15, 15–19, 15–21 | ||
| Pts: Gabriel, Jasen 12 Rebs: Caner-Medley 12 Asts: Granger 3 |
Pts: Wright 24 Rebs: Wright 11 Asts: Draper 5 | |
Palacio Vistalegre, Madrid
Attendance: 14,000 Referees: Recep Ankarali (TUR), Paolo Taurino (ITA), Carmelo Paternico (ITA) |
30 March 2011
20:30 |
| Benetton Basket Bwin |
84–62 | BG Göttingen |
| Scoring by quarter: 25–20, 20–17, 20–13, 19–12 | ||
| Pts: Smith 22 Rebs: Perić 8 Asts: Marković 10 |
Pts: Anderson 25 Rebs: Anderson 7 Asts: Five players 1 | |