Transcription factor IIIA is a protein that in humans is encoded by the GTF3A gene .[ 5] [ 6]
It was first purified and identified as the first mammalian gene-specific activator by Roeder in 1980,[ 7]
The TFIIIA in Xenopus zinc finger protein discovered.[ 8]
^ a b c GRCh38: Ensembl release 89: ENSG00000122034 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000016503 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Arakawa H, Nagase H, Hayashi N, Ogawa M, Nagata M, Fujiwara T, et al. (Jul 1995). "Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA". Cytogenetics and Cell Genetics . 70 (3–4): 235–8. doi :10.1159/000134041 . PMID 7789179 .
^ "Entrez Gene: GTF3A general transcription factor IIIA" .^ Engelke DR, Ng SY, Shastry BS, Roeder RG (Mar 1980). "Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes". Cell . 19 (3): 717–28. doi :10.1016/S0092-8674(80)80048-1 . PMID 6153931 . S2CID 23955175 . ^ Bruno M, Mahgoub M, Macfarlan TS (December 2019). "The Arms Race Between KRAB-Zinc Finger Proteins and Endogenous Retroelements and Its Impact on Mammals". Annual Review of Genetics . 53 (1). Annual Reviews : 393–416. doi :10.1146/annurev-genet-112618-043717 . PMID 31518518 . S2CID 202572327 .
Engelke DR, Ng SY, Shastry BS, Roeder RG (Mar 1980). "Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes". Cell . 19 (3): 717–28. doi :10.1016/S0092-8674(80)80048-1 . PMID 6153931 . S2CID 23955175 . Murphy JE, Keen JH (May 1992). "Recognition sites for clathrin-associated proteins AP-2 and AP-3 on clathrin triskelia" . The Journal of Biological Chemistry . 267 (15): 10850–5. doi :10.1016/S0021-9258(19)50096-5 PMID 1587861 . Seifart KH, Wang L, Waldschmidt R, Jahn D, Wingender E (January 1989). "Purification of human transcription factor IIIA and its interaction with a chemically synthesized gene encoding human 5 S rRNA" . The Journal of Biological Chemistry . 264 (3): 1702–9. doi :10.1016/S0021-9258(18)94243-2 PMID 2912980 . Drew PD, Nagle JW, Canning RD, Ozato K, Biddison WE, Becker KG (July 1995). "Cloning and expression analysis of a human cDNA homologous to Xenopus TFIIIA". Gene . 159 (2): 215–8. doi :10.1016/0378-1119(95)00145-V . PMID 7622052 . Moorefield B, Roeder RG (August 1994). "Purification and characterization of human transcription factor IIIA" . The Journal of Biological Chemistry . 269 (33): 20857–65. doi :10.1016/S0021-9258(17)31901-4 PMID 8063702 . Fridell RA, Fischer U, Lührmann R, Meyer BE, Meinkoth JL, Malim MH, Cullen BR (April 1996). "Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 Rev" . Proceedings of the National Academy of Sciences of the United States of America . 93 (7): 2936–40. Bibcode :1996PNAS...93.2936F . doi :10.1073/pnas.93.7.2936 PMC 39738 PMID 8610146 . Oettel S, Härtel F, Kober I, Iben S, Seifart KH (June 1997). "Human transcription factors IIIC2, IIIC1 and a novel component IIIC0 fulfil different aspects of DNA binding to various pol III genes" . Nucleic Acids Research . 25 (12): 2440–7. doi :10.1093/nar/25.12.2440 . PMC 146769 PMID 9171097 . Moreland RJ, Dresser ME, Rodgers JS, Roe BA, Conaway JW, Conaway RC, Hanas JS (May 2000). "Identification of a transcription factor IIIA-interacting protein" . Nucleic Acids Research . 28 (9): 1986–93. doi :10.1093/nar/28.9.1986 . PMC 103300 PMID 10756201 . Rao DS, Chang JC, Kumar PD, Mizukami I, Smithson GM, Bradley SV, et al. (November 2001). "Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors" . Molecular and Cellular Biology . 21 (22): 7796–806. doi :10.1128/MCB.21.22.7796-7806.2001 . PMC 99949 PMID 11604514 . Hanas JS, Hocker JR, Cheng YG, Lerner MR, Brackett DJ, Lightfoot SA, et al. (January 2002). "cDNA cloning, DNA binding, and evolution of mammalian transcription factor IIIA". Gene . 282 (1–2): 43–52. doi :10.1016/S0378-1119(01)00796-X . PMID 11814676 . Weser S, Riemann J, Seifart KH, Meissner W (May 2003). "Assembly and isolation of intermediate steps of transcription complexes formed on the human 5S rRNA gene" . Nucleic Acids Research . 31 (9): 2408–16. doi :10.1093/nar/gkg345 . PMC 154231 PMID 12711686 . Pellikainen JM, Ropponen KM, Kataja VV, Kellokoski JK, Eskelinen MJ, Kosma VM (November 2004). "Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis" . Clinical Cancer Research . 10 (22): 7621–8. doi :10.1158/1078-0432.CCR-04-1061 PMID 15569994 . Paing MM, Johnston CA, Siderovski DP, Trejo J (April 2006). "Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization" . Molecular and Cellular Biology . 26 (8): 3231–42. doi :10.1128/MCB.26.8.3231-3242.2006 . PMC 1446942 PMID 16581796 . Yamashita A, Takada T, Nemoto K, Yamamoto G, Torii R (July 2006). "Transient suppression of PPARgamma directed ES cells into an osteoblastic lineage". FEBS Letters . 580 (17): 4121–5. Bibcode :2006FEBSL.580.4121Y . doi :10.1016/j.febslet.2006.06.057 . PMID 16828750 . S2CID 84554520 . Schwartz B, Melnikova VO, Tellez C, Mourad-Zeidan A, Blehm K, Zhao YJ, et al. (June 2007). "Loss of AP-2alpha results in deregulation of E-cadherin and MMP-9 and an increase in tumorigenicity of colon cancer cells in vivo" . Oncogene . 26 (28): 4049–58. doi :10.1038/sj.onc.1210193 PMID 17224907 .
