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Haplogroup CZ

(Redirected from Haplogroup CZ (mtDNA))

In human mitochondrial genetics, the Haplogroup CZ is a human mitochondrial DNA (mtDNA) haplogroup.

Haplogroup CZ
AncestorM8
DescendantsC, Z
Defining mutations249d[1]

Origin

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Haplogroup CZ is a descendant of haplogroup M8 and is a parent to the haplogroups C and Z. The C and Z subclades share a common ancestor dated to approximately 36,500 years ago.[2][3]

Distribution

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Today, CZ is found in eastern Asian, Central Asian, Siberian, indigenous American, and European populations, and is most common in Siberian populations. It is recognized by a genetic marker at 249d.

Subclades

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Tree

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This phylogenetic tree of haplogroup CZ subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation[1] and subsequent published research.

  • M
    • M8
      • CZ
        • C
        • Z

See also

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Phylogenetic tree of human mitochondrial DNA (mtDNA) haplogroups

  Mitochondrial Eve (L)    
L0 L1–6  
L1 L2   L3     L4 L5 L6
M N  
CZ D E G Q   O A S R   I W X Y
C Z B F R0   pre-JT   P   U
HV JT K
H V J T

References

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  1. ^ a b van Oven, Mannis; Manfred Kayser (13 Oct 2008). "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation. 30 (2): E386–E394. doi:10.1002/humu.20921. PMID 18853457. S2CID 27566749.
  2. ^ Behar et al., 2012b
  3. ^ Sebastian Lippold; et al. (2014). "Human paternal and maternal demographic histories: insights from high-resolution Y chromosome and mtDNA sequences". bioRxiv 10.1101/001792.
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