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Counterirritant

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A counterirritant is a substance which creates inflammation in one location with the goal of lessening the inflammation in another location.[1] . This strategy falls into the more general category of counterstimulation.

Capsaicin is an example of a counterirritant.[2]

Template:Cleanup-remainder B COUNTER IRRITANT Described by "Federal Register / Vol. 44, No. 234 / Tuesday, December 4, 1979, FDA", Counter Irritant is "An externally applied substance that causes irritation or mild inflammation of the skin for the purpose of relieving pain in muscles, joints and viscera distal to the site of application. They differ from the anesthetics, analgesics, and antipruritic agents, however, in that the pain relief they produce results from stimulation --- rather than depression --- of the cutaneous sensory receptors and occurs in structures of the body other than the skin areas to which they are applied as for example, in joints, muscles, tendons and certain viscera. The use of these products dates from antiquity."

References

  1. ^ WordNet Search - 3.0
  2. ^ Prasad BC, Kumar V, Gururaj HB, Parimalan R, Giridhar P, Ravishankar GA (2006). "Characterization of capsaicin synthase and identification of its gene (csy1) for pungency factor capsaicin in pepper (Capsicum sp.)". Proc. Natl. Acad. Sci. U.S.A. 103 (36): 13315–20. doi:10.1073/pnas.0605805103. PMC 1569161. PMID 16938870.{{cite journal}}: CS1 maint: multiple names: authors list (link) (Retracted. If this is an intentional citation to a retracted paper, please replace {{retracted|...}} with {{retracted|...|intentional=yes}}.)


Federal Register / Vol. 44, No. 234 / Tuesday, December 4, 1979, FDA