Scrambler mouse
Scrambler is a spontaneous mutant lacking a functional DAB1 gene, resulting in a phenotype resembling that seen in the Reeler Mouse.[1]
The strain was first described by Sweet et al in 1996.[2]
References
- ^ González JL, Russo CJ, Goldowitz D, Sweet HO, Davisson MT, Walsh CA. Birthdate and cell marker analysis of scrambler: a novel mutation affecting cortical development with a reeler-like phenotype. J. Neurosci. 17, 9204–11, 1997, pmid=9364067 |doi=|url=http://www.jneurosci.org/cgi/pmidlookup?view=long&pmid=9364067}}
- ^ Sweet HO, Bronson RT, Johnson KR, Cook SA, Davisson MT |title=Scrambler, a new neurological mutation of the mouse with abnormalities of neuronal migration. Mamm. Genome 7, 798–802, 1996, pmid=8875886 |doi=10.1007/s003359900240|url=http://link.springer-ny.com/link/service/journals/00335/bibs/7n11p798.html}}