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'''''Withania somnifera''''', known commonly as '''ashwagandha''' or '''winter cherry''',<ref name=GRIN>{{GRIN | access-date = 2011-10-29 }}</ref><ref name="drugs">{{cite web |title=Ashwagandha |url=https://www.drugs.com/npp/ashwagandha.html |publisher=Drugs.com |access-date=2 February 2021 |date=2 November 2020}}</ref><ref name="mlp">{{cite web|date=28 August 2020|title=Ashwagandha|url=https://medlineplus.gov/druginfo/natural/953.html|access-date=21 September 2020|publisher=MedlinePlus, US National Library of Medicine}}</ref> is an evergreen shrub in the [[Solanaceae]] or nightshade family that grows in India, the Middle East, and parts of Africa. Several other species in the genus ''Withania'' are morphologically similar.<ref name=drugs/>
'''''Withania somnifera''''', known commonly as '''ashwagandha''' or '''winter cherry''',<ref name=GRIN>{{GRIN | access-date = 2011-10-29 }}</ref><ref name="drugs">{{cite web |title=Ashwagandha |url=https://www.drugs.com/npp/ashwagandha.html |publisher=Drugs.com |access-date=2 February 2021 |date=2 November 2020}}</ref><ref name="mlp">{{cite web|date=28 August 2020|title=Ashwagandha|url=https://medlineplus.gov/druginfo/natural/953.html|access-date=21 September 2020|publisher=MedlinePlus, US National Library of Medicine}}</ref> is an evergreen shrub in the [[Solanaceae]] or nightshade family that grows in India, the Middle East, and parts of Africa. Several other species in the genus ''Withania'' are morphologically similar.<ref name=drugs/>


The plant, particularly its root powder, has been used for centuries in [[Ayurveda|traditional Indian medicine]]. It is used in [[herbalism]] and sold as a [[dietary supplement]] to treat a variety of conditions. While there is not enough evidence to constitute a scientific consensus that it is safe and effective for treating any health condition or disease, systematic reviews of clinical trials and other studies suggest that it may be effective in addressing insomnia and reducing stress. <ref name="drugs" /><ref name="mlp" /><ref>https://onlinelibrary.wiley.com/doi/abs/10.1002/ptr.7598</ref>
The plant, particularly its root powder, has been used for centuries in [[Ayurveda|traditional Indian medicine]]. Although used in [[herbalism]] and sold as a [[dietary supplement]], there is insufficient scientific evidence that it is safe or effective for treating any health condition or disease.<ref name="drugs" /><ref name="mlp" />


== Description ==
== Description ==

Revision as of 04:19, 3 October 2023

Withania somnifera
Scientific classification Edit this classification
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Asterids
Order: Solanales
Family: Solanaceae
Genus: Withania
Species:
W. somnifera
Binomial name
Withania somnifera
Synonyms[1]
  • Physalis somnifera L.
  • Withania kansuensis Kuang & A. M. Lu
  • Withania microphysalis Suess.
Flower

Withania somnifera, known commonly as ashwagandha or winter cherry,[2][3][4] is an evergreen shrub in the Solanaceae or nightshade family that grows in India, the Middle East, and parts of Africa. Several other species in the genus Withania are morphologically similar.[3]

The plant, particularly its root powder, has been used for centuries in traditional Indian medicine. Although used in herbalism and sold as a dietary supplement, there is insufficient scientific evidence that it is safe or effective for treating any health condition or disease.[3][4]

Description

This species is a short shrub growing 35–75 cm (14–30 in) tall. Tomentose branches extend radially from a central stem. Leaves are dull green, elliptic, usually up to 10–12 cm (3.9–4.7 in) long. The flowers are small, green and bell-shaped. The ripe fruit is orange-red.[3]

Etymology

Look up ashwagandha in Wiktionary, the free dictionary.

The Latin species name somnifera means "sleep-inducing".[5] The name "ashwagandha" is a combination of the Sanskrit words 'ashva', meaning horse, and 'gandha', meaning smell, reflecting that the root has a strong horse-like odor.[3]

Cultivation

Withania somnifera is cultivated in many of the drier regions of India. It is also found in Nepal, Sri Lanka, China,[6] and Yemen.[7] It prefers dry stony soil with sun to partial shade. To propagate it can be grown from seed in the early spring, or from greenwood cuttings in the later spring.[8]

Diseases and pests

Withania somnifera is prone to several pests and diseases. Leaf spot disease caused by Alternaria alternata is the most prevalent disease, which occurs in a severe form in Punjab, Haryana, and Himachal Pradesh. A decline in the concentration of its secondary metabolites occurs by leaf spot disease.[9] The leaves are also prone to Alternaria dianthicola in India.[10]

A treehopper (Oxyrachis tarandus) feeds on the apical portions of the stem, making them rough and woody in appearance and brown in colour.[11]

The carmine red spider mite (Tetranychus urticae) is the most prevalent pest of the plant in India.[12] In recent years, this plant has been serving as a new reservoir host for an invasive mealybug species Phenacoccus solenopsis.[13]

Phytochemistry

The main phytochemical constituents are withanolides – which are triterpene lactones – withaferin A, alkaloids, steroidal lactones, tropine, and cuscohygrine.[3] Some 40 withanolides, 12 alkaloids, and numerous sitoindosides have been isolated.[3] Withanolides are structurally similar to the ginsenosides of Panax ginseng, leading to a common name for W. somnifera, "Indian ginseng".[3]

Adverse effects

W. somnifera may cause adverse effects if taken alone or together with prescription drugs.[3][4][14] Side effects may include diarrhea, headache, sedation, or nausea, and the product should not be used during pregnancy or breastfeeding.[4][14]

  • Fruits
    Fruits
  • Druggist's jar containing dried roots of Withania somnifera
    Druggist's jar containing dried roots of Withania somnifera
  • Dried graded roots of Withania somnifera
    Dried graded roots of Withania somnifera

References

  1. ^ "Withania somnifera (L.) Dunal". Tropicos. Missouri Botanical Garden. Retrieved 25 Feb 2012.
  2. ^ "Withania somnifera". Germplasm Resources Information Network. Agricultural Research Service, United States Department of Agriculture. Retrieved 2011-10-29.
  3. ^ a b c d e f g h i "Ashwagandha". Drugs.com. 2 November 2020. Retrieved 2 February 2021.
  4. ^ a b c d "Ashwagandha". MedlinePlus, US National Library of Medicine. 28 August 2020. Retrieved 21 September 2020.
  5. ^ Stearn, W. T. (1995). Botanical Latin: History, Grammar, Syntax, Terminology and Vocabulary (4th ed.). Timber Press. ISBN 978-0-88192-321-6.
  6. ^ Pandit, S.; Chang, K.-W.; Jeon, J.-G. (February 2013). "Effects of Withania somnifera on the growth and virulence properties of Streptococcus mutans and Streptococcus sobrinus at sub-MIC levels". Anaerobe. 19: 1–8. doi:10.1016/j.anaerobe.2012.10.007. PMID 23142795.
  7. ^ Hugh Scott & Kenneth Mason, Western Arabia and the Red Sea, Naval Intelligence Division: London 1946, p. 597 ISBN 0-7103-1034-X.
  8. ^ Deni., Bown (1995). Encyclopedia of herbs & their uses. Montréal: RD Press. ISBN 0888503342. OCLC 32547547.
  9. ^ Pati, P. K.; Sharma, M.; Salar, R. K.; Sharma, A.; Gupta, A. P.; Singh, B. (2009). "Studies on leaf spot disease of Withania somnifera and its impact on secondary metabolites". Indian Journal of Microbiology. 48 (4): 432–437. doi:10.1007/s12088-008-0053-y. PMC 3476785. PMID 23100743.
  10. ^ Maiti, C. K.; Sen, S.; Paul, A. K.; Acharya, K. (2007-04-01). "First Report of Alternaria dianthicola Causing Leaf Blight on Withania somnifera from India". Plant Disease. 91 (4): 467. doi:10.1094/PDIS-91-4-0467B. ISSN 0191-2917. PMID 30781215.
  11. ^ Sharma, A; Pati, P.K. (2011). "First report of Withania somnifera (L.) Dunal, as a New Host of Cowbug (Oxyrachis tarandus, Fab.) in plains of Punjab, Northern India". World Applied Sci. J. 14 (9): 1344–1346.
  12. ^ Sharma, A.; Pati, P. K. (2012). "First record of the carmine spider mite, Tetranychus urticae, infesting Withania somnifera in India". Journal of Insect Science. 12 (50): 1–4. doi:10.1673/031.012.5001. PMC 3476950. PMID 22970740.
  13. ^ Sharma, A.; Pati, P. K. (2013). "First record of Ashwagandha as a new host to the invasive mealybug (Phenacoccus solenopsis Tinsley) in India". Entomological News. 123 (1): 59–62. doi:10.3157/021.123.0114. S2CID 85645762.
  14. ^ a b "Ashwagandha". New York City: Memorial Sloan Kettering Cancer Center. 13 April 2018. Retrieved 26 May 2018.
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