(S)-carnitine 3-dehydrogenase
Appearance
(S)-carnitine 3-dehydrogenase | |||||||||
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Identifiers | |||||||||
EC no. | 1.1.1.254 | ||||||||
CAS no. | 169277-49-0 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a (S)-carnitine 3-dehydrogenase (EC 1.1.1.254) is an enzyme that catalyzes the chemical reaction
- (S)-carnitine + NAD+ 3-dehydrocarnitine + NADH + H+
Thus, the two substrates of this enzyme are (S)-carnitine and NAD+, whereas its 3 products are 3-dehydrocarnitine, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (S)-carnitine:NAD+ oxidoreductase.
References
[edit]- Setyahadi S, Ueyama T, Arimoto T, Mori N, Kitamoto Y (1997). "Purification and properties of a new enzyme, D-carnitine dehydrogenase, from Agrobacterium sp. 525a". Biosci. Biotechnol. Biochem. 61 (6): 1055–8. doi:10.1271/bbb.61.1055. PMID 9214773.