string virtualEnvPath = $@".\myDir\.venv";
    string venvSitePackagesPath = $@"{sVirtualEnvPath}\Lib\site-packages";

    // Resolve editable dependencies manually because Python.NET doesn't do so
    string[] editableDependencyReferences = Directory.GetFiles(venvSitePackagesPath, "*.pth");
    string[] editableDependencyPaths = editableDependencyReferences
      .Select(filePath => File.ReadAllText(filePath).Trim())
      .ToArray();

    string pythonPath = $"{venvSitePackagesPath};" +
                         @"C:\Program Files\Python312\Lib;" +
                         @"C:\Program Files\Python312\DLLs;" +
                         string.Join(";", editableDependencyPaths); // Add them to the path

    Environment.SetEnvironmentVariable("PATH", 
                                       Environment.GetEnvironmentVariable("PATH").TrimEnd(';') + ";" +
                                       virtualEnvPath, EnvironmentVariableTarget.Process);
    Environment.SetEnvironmentVariable("PYTHONHOME", virtualEnvPath, EnvironmentVariableTarget.Process);
    Environment.SetEnvironmentVariable("PYTHONPATH", pythonPath, EnvironmentVariableTarget.Process);

    PythonEngine.PythonHome = virtualEnvPath;
    PythonEngine.PythonPath = pythonPath;
    PythonEngine.Initialize();

    using (Py.GIL())
    {
      dynamic mymodule = Py.Import("mymodule"); // Succeeds now!
    }