A617 A retrospective, cross-sectional analysis of Brazil National Health and Wellness Survey data... more A617 A retrospective, cross-sectional analysis of Brazil National Health and Wellness Survey data was conducted. Economic outcomes included work productivity and activity impairment (past 7 days) and self-reported healthcare use (past 6 months). Humanistic outcomes included Health-related quality of life (HRQoL) using SF-12v2 or SF-36v2 (4-week recall version), and self-reported psychological complaints (past 12 months). Adult patients currently treated for CU were matched 1:4 to controls (never experienced CU) by survey year, age, sex, private insurance and socioeconomic status. Generalized linear models were conducted to compare the patients and matched controls, adjusting for race, income, smoking, obesity, and other comorbidities, using distributions and link functions appropriate for each outcome. Results: Among the patients currently treated for CU (N= 127) and matched controls (N= 508), 80.3% and 78.9% respectively were in labor force (p= 0.73). Employed patients reported significantly higher presenteeism (33.9% vs 21.0%), and overall work impairment (39.1% vs 25.9%); patients also reported higher activity impairment (35.5% vs 23.7%) relative to controls (all p< 0.01). Mean healthcare practitioner (9.7 vs 5.0), emergency room (1.32 vs 0.63) and allergist visits (0.54 vs 0.07) were higher in patients compared to controls (all p< 0.01). Patients had worse HRQoL, including lower mental (5 points) and physical (2.5 points) component summary scores (both p< 0.01), lower (0.06 points) health utility scores (p< 0.001), and were more likely to report anxiety (adjusted odds ratio [OR] = 2.7) and sleep difficulties (OR= 2.2) than controls (both p< 0.001). ConClusions: CSU is likely to impose substantial economic and humanistic burden in Brazilian adults with high impact on patients' HRQoL and on society.
Background/objective Cardiovascular diseases (CVD) are the leading cause of mortality in European... more Background/objective Cardiovascular diseases (CVD) are the leading cause of mortality in European countries. This study aimed at estimating the 10-year risk of fatal CVD in Portuguese adults and to assess the prevalence of major cardiovascular risk factors, according to the SCORE® risk prediction system. Subjects and methods A cross-sectional survey was carried out in 60 community pharmacies (CP) from October 2005 to January 2006 in a sample of CP users (≥40 and ≤65 years). Data were collected by patient interviews using a structured questionnaire applied by a trained pharmacist. Results A total of 1,043 individuals were enrolled in the study (participation rate: 91%). The mean age was 53.7 years (SD: 7.1) with a ratio men/women of 0.68. The average risk in the sample was 1.94 (minimum 0, maximum 28, SD=2.69). About 20% of the studied adults were at high risk, of which 39.4% were asymptomatic. CV risk was significantly higher in the oldest age group and in men (p< 0.05). The prevalence of main CV risk factors was: hypertension-54.8%; hypercholesterolemia-63.1%, diabetes-13.4%; smoking-10.4% and obesity-29.0%. About 1/3 of those asked had family history of premature CVD. Mean values of biochemical and clinical parameters were: systolic blood pressure (mmHg): 134.8± 19.7; diastolic blood pressure (mmHg): 81.0±11.4; total cholesterol (mg/dl): 193.8±34.6; body mass index (kg/m 2): 28.0±4.5. Conclusions According to SCORE®, about one-fifth of the individuals was classified as high risk, and 7.7% was asymptomatic. CV risk was significantly higher in the oldest age group (55-65 years old) and in men (p<0.05). These results show a high prevalence of some risk factors, particularly hypertension and hypercholesterolemia.
This study aimed to test a novel method of compliance measurement in Portuguese community pharmac... more This study aimed to test a novel method of compliance measurement in Portuguese community pharmacy in Helicobacter pylori patients. A case series design was used where compliance indicators were electronically measured, aside with patients' reports. Experienced adverse drug reactions, perceived benefit of therapy and quality of life were also measured. Mean compliance proportion was 56% and a positive impact on…
This study aimed to test a novel method of compliance measurement in Portuguese community pharmac... more This study aimed to test a novel method of compliance measurement in Portuguese community pharmacy in Helicobacter pylori patients. A case series design was used where compliance indicators were electronically measured, aside with patients' reports. Experienced adverse drug reactions, perceived benefit of therapy and quality of life were also measured. Mean compliance proportion was 56% and a positive impact on patients' perceived health status was found. The method used was welcomed by community pharmacists, albeit having an influence on patients' normal behaviour.
Background/objective Cardiovascular diseases (CVD) are the leading cause of mortality in European... more Background/objective Cardiovascular diseases (CVD) are the leading cause of mortality in European countries. This study aimed at estimating the 10-year risk of fatal CVD in Portuguese adults and to assess the prevalence of major cardiovascular risk factors, according to the SCORE® risk prediction system.
A617 A retrospective, cross-sectional analysis of Brazil National Health and Wellness Survey data... more A617 A retrospective, cross-sectional analysis of Brazil National Health and Wellness Survey data was conducted. Economic outcomes included work productivity and activity impairment (past 7 days) and self-reported healthcare use (past 6 months). Humanistic outcomes included Health-related quality of life (HRQoL) using SF-12v2 or SF-36v2 (4-week recall version), and self-reported psychological complaints (past 12 months). Adult patients currently treated for CU were matched 1:4 to controls (never experienced CU) by survey year, age, sex, private insurance and socioeconomic status. Generalized linear models were conducted to compare the patients and matched controls, adjusting for race, income, smoking, obesity, and other comorbidities, using distributions and link functions appropriate for each outcome. Results: Among the patients currently treated for CU (N= 127) and matched controls (N= 508), 80.3% and 78.9% respectively were in labor force (p= 0.73). Employed patients reported significantly higher presenteeism (33.9% vs 21.0%), and overall work impairment (39.1% vs 25.9%); patients also reported higher activity impairment (35.5% vs 23.7%) relative to controls (all p< 0.01). Mean healthcare practitioner (9.7 vs 5.0), emergency room (1.32 vs 0.63) and allergist visits (0.54 vs 0.07) were higher in patients compared to controls (all p< 0.01). Patients had worse HRQoL, including lower mental (5 points) and physical (2.5 points) component summary scores (both p< 0.01), lower (0.06 points) health utility scores (p< 0.001), and were more likely to report anxiety (adjusted odds ratio [OR] = 2.7) and sleep difficulties (OR= 2.2) than controls (both p< 0.001). ConClusions: CSU is likely to impose substantial economic and humanistic burden in Brazilian adults with high impact on patients' HRQoL and on society.
Background/objective Cardiovascular diseases (CVD) are the leading cause of mortality in European... more Background/objective Cardiovascular diseases (CVD) are the leading cause of mortality in European countries. This study aimed at estimating the 10-year risk of fatal CVD in Portuguese adults and to assess the prevalence of major cardiovascular risk factors, according to the SCORE® risk prediction system. Subjects and methods A cross-sectional survey was carried out in 60 community pharmacies (CP) from October 2005 to January 2006 in a sample of CP users (≥40 and ≤65 years). Data were collected by patient interviews using a structured questionnaire applied by a trained pharmacist. Results A total of 1,043 individuals were enrolled in the study (participation rate: 91%). The mean age was 53.7 years (SD: 7.1) with a ratio men/women of 0.68. The average risk in the sample was 1.94 (minimum 0, maximum 28, SD=2.69). About 20% of the studied adults were at high risk, of which 39.4% were asymptomatic. CV risk was significantly higher in the oldest age group and in men (p< 0.05). The prevalence of main CV risk factors was: hypertension-54.8%; hypercholesterolemia-63.1%, diabetes-13.4%; smoking-10.4% and obesity-29.0%. About 1/3 of those asked had family history of premature CVD. Mean values of biochemical and clinical parameters were: systolic blood pressure (mmHg): 134.8± 19.7; diastolic blood pressure (mmHg): 81.0±11.4; total cholesterol (mg/dl): 193.8±34.6; body mass index (kg/m 2): 28.0±4.5. Conclusions According to SCORE®, about one-fifth of the individuals was classified as high risk, and 7.7% was asymptomatic. CV risk was significantly higher in the oldest age group (55-65 years old) and in men (p<0.05). These results show a high prevalence of some risk factors, particularly hypertension and hypercholesterolemia.
This study aimed to test a novel method of compliance measurement in Portuguese community pharmac... more This study aimed to test a novel method of compliance measurement in Portuguese community pharmacy in Helicobacter pylori patients. A case series design was used where compliance indicators were electronically measured, aside with patients' reports. Experienced adverse drug reactions, perceived benefit of therapy and quality of life were also measured. Mean compliance proportion was 56% and a positive impact on…
This study aimed to test a novel method of compliance measurement in Portuguese community pharmac... more This study aimed to test a novel method of compliance measurement in Portuguese community pharmacy in Helicobacter pylori patients. A case series design was used where compliance indicators were electronically measured, aside with patients' reports. Experienced adverse drug reactions, perceived benefit of therapy and quality of life were also measured. Mean compliance proportion was 56% and a positive impact on patients' perceived health status was found. The method used was welcomed by community pharmacists, albeit having an influence on patients' normal behaviour.
Background/objective Cardiovascular diseases (CVD) are the leading cause of mortality in European... more Background/objective Cardiovascular diseases (CVD) are the leading cause of mortality in European countries. This study aimed at estimating the 10-year risk of fatal CVD in Portuguese adults and to assess the prevalence of major cardiovascular risk factors, according to the SCORE® risk prediction system.
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