Papers by Isabel Maria Carrion Madroñal
Revista Espanola De Quimioterapia, 2020
Revista española de quimioterapia : publicación oficial de la Sociedad Española de Quimioterapia, Mar 24, 2020
Revista Española de Geriatría y Gerontología, Mar 1, 2023
OBJECTIVE: To assess the quality of medication prescribing in ambulatory elderly patients on mult... more OBJECTIVE: To assess the quality of medication prescribing in ambulatory elderly patients on multiple medications using the Medication Appropriateness Index (MAl). DESIGN: Cross-sectional study. SETTING: General Medical Clinic of the Durham VA Medical Center. PATIENTS: 208 elderly outpatients on five or more regularly scheduled medications. MEASUREMENTS: Medication prescribing appropriateness was measured with the MAl, a reliable method that employs 10 implicit criteria. A weighted MAl score (range 0-18 per drug) served as a summary measure of appropriateness. RESULTS: There were 1644 medications evaluated; 26% received no inappropriate ratings, 37% had one, 19% had two, and 18% had three or more. Of 16,440 ratings, 2295 (14%) were evaluated as inappropriate. The percentage of inappropriate ratings varied across prescribing dimensions: drug-drug interactions, 00/0; drug-disease interactions, 1.4%; medication effectiveness, 4.7%; therapeutic duplication, 5.7%; indication, 11.50/0; duration of treatment, 16.5%; dosage, 17.3%; practical directions, 20.3%; cost, 29.7%; and correct directions, 32.4%. The mean MAl score for all medications was 2.2 ± 2.1 (range 0-10) and varied by therapeutic class. MAl scores were significantly lower for medications with a high potential for adverse effects compared with those with a low potential (MAl score of 1.8 vs 2.9, P < 0.001). Regression analysis revealed that no patient characteristics were associated with a higher likelihood of inappropriate prescribing. CONCLUSIONS: Medication prescribing for elderly outpatients taking multiple medications was substantially appropriate. Prescribing dimensions with the most room for
European journal of clinical pharmacy: atención farmacéutica, 2019
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Papers by Isabel Maria Carrion Madroñal