In this work, in order to prepare biocomposites of ciprofloxacin- montmorillonite/N,N,N-triethyl ... more In this work, in order to prepare biocomposites of ciprofloxacin- montmorillonite/N,N,N-triethyl chitosan (CMC/TEC and CMC׳/TEC), ciprofloxacin was intercalated into the Na+-montmorillonite layers in two different pHs and coated with N,N,N-triethyl chitosan. XRD and FT-IR data demonstrated that ciprofloxacin (CIP) diffused among the layers of montmorillonite. The prepared biocomposites were further characterised by TG, SEM, BET, DSC, and disk diffusion method to investigate antibacterial activity against Staphylococcus aureus as well. Coated composites with N,N,N-triethyl chitosan possessed efficiency of the drug encapsulation, and controlled the release of drug from the biocomposites in comparison with composites without N,N,N-triethyl chitosan. Study of antibacterial activities of two biocomposites of CMC1/TEC and CMC2/TEC with lower release rates and lower concentrations of CIP than other biocomposites revealed that likely N,N,N-triethyl chitosan could considerably help to reduce the consumption of ciprofloxacin. By doing more researches on other bacterial strains and performing advanced tests on our own biocomposites, N,N,N-triethyl chitosan can probably be proved as a suitable candidate for a substitute in biomedical activities.
In this work and in continuation of our strategy for improving the performance of heterogeneous c... more In this work and in continuation of our strategy for improving the performance of heterogeneous catalysts, the SiO 2 @GO-OSO 3 H catalyst was applied as a very efficient solid acid catalyst for the Beckmann rearrangement. This catalyst effectively catalyzed the liquid-phase Beckmann rearrangement of cyclohexanone oxime to capro-lactam in high yield under very mild conditions. The improvement of GO-OSO 3 H catalyst in regard to its separation from reaction mixture is achieved by coating it with a mesoporous SiO 2 layer. The influence of the operating parameters on the performance of the catalyst namely solvent, temperature, amount of catalyst, and time was studied.
In this work and in continuation of our strategy for improving the performance of heterogeneous c... more In this work and in continuation of our strategy for improving the performance of heterogeneous catalysts, the SiO 2 @GO-OSO 3 H catalyst was applied as a very efficient solid acid catalyst for the Beckmann rearrangement. This catalyst effectively catalyzed the liquid-phase Beckmann rearrangement of cyclohexanone oxime to capro-lactam in high yield under very mild conditions. The improvement of GO-OSO 3 H catalyst in regard to its separation from reaction mixture is achieved by coating it with a mesoporous SiO 2 layer. The influence of the operating parameters on the performance of the catalyst namely solvent, temperature, amount of catalyst, and time was studied.
Abstract In this work and in continuation of our strategy for improving the performance of hetero... more Abstract In this work and in continuation of our strategy for improving the performance of heterogeneous catalysts, the SiO 2 @GO-OSO 3 H catalyst was applied as a very efficient solid acid catalyst for the Beckmann rearrangement. This catalyst effectively catalyzed the liquid-phase Beckmann rearrangement of cyclohexanone oxime to caprolactam in high yield under very mild conditions. The improvement of GO-OSO 3 H catalyst in regard to its separation from reaction mixture is achieved by coating it with a mesoporous SiO 2 layer. The influence of the operating parameters on the performance of the catalyst namely solvent, temperature, amount of catalyst, and time was studied.
In this work, in order to prepare biocomposites of ciprofloxacin-montmorillonite/N,N,N-triethyl c... more In this work, in order to prepare biocomposites of ciprofloxacin-montmorillonite/N,N,N-triethyl chitosan (CMC/ TEC and CMC/׳TEC), ciprofloxacin was intercalated into the Na +-montmorillonite layers in two different pHs and coated with N,N,N-triethyl chitosan. XRD and FT-IR data demonstrated that ciprofloxacin (CIP) diffused among the layers of montmorillonite. The prepared biocomposites were further characterised by TG, SEM, BET, DSC, and disk diffusion method to investigate antibacterial activity against Staphylococcus aureus as well. Coated composites with N,N,N-triethyl chitosan possessed efficiency of the drug encapsulation, and controlled the release of drug from the biocomposites in comparison with composites without N,N,N-triethyl chitosan. Study of antibacterial activities of two biocomposites of CMC1/TEC and CMC2/TEC with lower release rates and lower concentrations of CIP than other biocomposites revealed that likely N,N,N-triethyl chitosan could considerably help to reduce the consumption of ciprofloxacin. By doing more researches on other bacterial strains and performing advanced tests on our own biocomposites, N,N,N-triethyl chitosan can probably be proved as a suitable candidate for a substitute in biomedical activities.
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was e... more ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
In this work and in continuation of our strategy for improving the performance of heterogeneous c... more In this work and in continuation of our strategy for improving the performance of heterogeneous catalysts, the SiO 2 @GO-OSO 3 H catalyst was applied as a very efficient solid acid catalyst for the Beckmann rearrangement. This catalyst effectively catalyzed the liquid-phase Beckmann rearrangement of cyclohexanone oxime to capro-lactam in high yield under very mild conditions. The improvement of GO-OSO 3 H catalyst in regard to its separation from reaction mixture is achieved by coating it with a mesoporous SiO 2 layer. The influence of the operating parameters on the performance of the catalyst namely solvent, temperature, amount of catalyst, and time was studied.
In this study, a new methodology was applied for controlling the release of different drugs by
en... more In this study, a new methodology was applied for controlling the release of different drugs by encapsulating them in organic-inorganic hybrids via sol-gel technique. The assembled organic-inorganic hybrids had diverse BET surface area, porosity, and high heat resistance. The synthesized organic-inorganic hybrids were based on zirconium(IV) propoxide, and tetraethyl orthosilicate as precursor of inorganic network, and chitosan or N-triethylchitosan as organic or biopolymer components. In these hybrid composites, drug and biopolymer were coated with a mesoporous inorganic material. FT-IR, FE-SEM, DSC, BET, XRD techniques, and Zeta potential analysis used for investigating the formation of metformin/chitosan@ZrO2 and sodium naproxen/N-triethylchitosan@SiO2 hybrid composites. Then for investigating the role of sol-gel process, the release of metformin and sodium naproxen in the prepared hybrid composites was investigated as model drugs. Compare to drug/biopolymer composite, incorporation of ZrO2 or SiO2 coating enhanced the drug entrapment appreciably, and naturally reduced the rate of drug release. For example, the metformin/chitosan composite without ZrO2 coating released the whole drug in less than10 h in pH 7.4 when the composite coated with ZrO2 released the entrapped drug after 25 h.
In this work and in continuation of our strategy for improving the performance of heterogeneous c... more In this work and in continuation of our strategy for improving the performance of heterogeneous catalysts, the SiO 2 @GO-OSO 3 H catalyst was applied as a very efficient solid acid catalyst for the Beckmann rearrangement. This catalyst effectively catalyzed the liquid-phase Beckmann rearrangement of cyclohexanone oxime to capro-lactam in high yield under very mild conditions. The improvement of GO-OSO 3 H catalyst in regard to its separation from reaction mixture is achieved by coating it with a mesoporous SiO 2 layer. The influence of the operating parameters on the performance of the catalyst namely solvent, temperature, amount of catalyst, and time was studied.
In this work, in order to prepare biocomposites of ciprofloxacin- montmorillonite/N,N,N-triethyl ... more In this work, in order to prepare biocomposites of ciprofloxacin- montmorillonite/N,N,N-triethyl chitosan (CMC/TEC and CMC׳/TEC), ciprofloxacin was intercalated into the Na+-montmorillonite layers in two different pHs and coated with N,N,N-triethyl chitosan. XRD and FT-IR data demonstrated that ciprofloxacin (CIP) diffused among the layers of montmorillonite. The prepared biocomposites were further characterised by TG, SEM, BET, DSC, and disk diffusion method to investigate antibacterial activity against Staphylococcus aureus as well. Coated composites with N,N,N-triethyl chitosan possessed efficiency of the drug encapsulation, and controlled the release of drug from the biocomposites in comparison with composites without N,N,N-triethyl chitosan. Study of antibacterial activities of two biocomposites of CMC1/TEC and CMC2/TEC with lower release rates and lower concentrations of CIP than other biocomposites revealed that likely N,N,N-triethyl chitosan could considerably help to reduce the consumption of ciprofloxacin. By doing more researches on other bacterial strains and performing advanced tests on our own biocomposites, N,N,N-triethyl chitosan can probably be proved as a suitable candidate for a substitute in biomedical activities.
In this work and in continuation of our strategy for improving the performance of heterogeneous c... more In this work and in continuation of our strategy for improving the performance of heterogeneous catalysts, the SiO 2 @GO-OSO 3 H catalyst was applied as a very efficient solid acid catalyst for the Beckmann rearrangement. This catalyst effectively catalyzed the liquid-phase Beckmann rearrangement of cyclohexanone oxime to capro-lactam in high yield under very mild conditions. The improvement of GO-OSO 3 H catalyst in regard to its separation from reaction mixture is achieved by coating it with a mesoporous SiO 2 layer. The influence of the operating parameters on the performance of the catalyst namely solvent, temperature, amount of catalyst, and time was studied.
In this work and in continuation of our strategy for improving the performance of heterogeneous c... more In this work and in continuation of our strategy for improving the performance of heterogeneous catalysts, the SiO 2 @GO-OSO 3 H catalyst was applied as a very efficient solid acid catalyst for the Beckmann rearrangement. This catalyst effectively catalyzed the liquid-phase Beckmann rearrangement of cyclohexanone oxime to capro-lactam in high yield under very mild conditions. The improvement of GO-OSO 3 H catalyst in regard to its separation from reaction mixture is achieved by coating it with a mesoporous SiO 2 layer. The influence of the operating parameters on the performance of the catalyst namely solvent, temperature, amount of catalyst, and time was studied.
Abstract In this work and in continuation of our strategy for improving the performance of hetero... more Abstract In this work and in continuation of our strategy for improving the performance of heterogeneous catalysts, the SiO 2 @GO-OSO 3 H catalyst was applied as a very efficient solid acid catalyst for the Beckmann rearrangement. This catalyst effectively catalyzed the liquid-phase Beckmann rearrangement of cyclohexanone oxime to caprolactam in high yield under very mild conditions. The improvement of GO-OSO 3 H catalyst in regard to its separation from reaction mixture is achieved by coating it with a mesoporous SiO 2 layer. The influence of the operating parameters on the performance of the catalyst namely solvent, temperature, amount of catalyst, and time was studied.
In this work, in order to prepare biocomposites of ciprofloxacin-montmorillonite/N,N,N-triethyl c... more In this work, in order to prepare biocomposites of ciprofloxacin-montmorillonite/N,N,N-triethyl chitosan (CMC/ TEC and CMC/׳TEC), ciprofloxacin was intercalated into the Na +-montmorillonite layers in two different pHs and coated with N,N,N-triethyl chitosan. XRD and FT-IR data demonstrated that ciprofloxacin (CIP) diffused among the layers of montmorillonite. The prepared biocomposites were further characterised by TG, SEM, BET, DSC, and disk diffusion method to investigate antibacterial activity against Staphylococcus aureus as well. Coated composites with N,N,N-triethyl chitosan possessed efficiency of the drug encapsulation, and controlled the release of drug from the biocomposites in comparison with composites without N,N,N-triethyl chitosan. Study of antibacterial activities of two biocomposites of CMC1/TEC and CMC2/TEC with lower release rates and lower concentrations of CIP than other biocomposites revealed that likely N,N,N-triethyl chitosan could considerably help to reduce the consumption of ciprofloxacin. By doing more researches on other bacterial strains and performing advanced tests on our own biocomposites, N,N,N-triethyl chitosan can probably be proved as a suitable candidate for a substitute in biomedical activities.
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was e... more ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
In this work and in continuation of our strategy for improving the performance of heterogeneous c... more In this work and in continuation of our strategy for improving the performance of heterogeneous catalysts, the SiO 2 @GO-OSO 3 H catalyst was applied as a very efficient solid acid catalyst for the Beckmann rearrangement. This catalyst effectively catalyzed the liquid-phase Beckmann rearrangement of cyclohexanone oxime to capro-lactam in high yield under very mild conditions. The improvement of GO-OSO 3 H catalyst in regard to its separation from reaction mixture is achieved by coating it with a mesoporous SiO 2 layer. The influence of the operating parameters on the performance of the catalyst namely solvent, temperature, amount of catalyst, and time was studied.
In this study, a new methodology was applied for controlling the release of different drugs by
en... more In this study, a new methodology was applied for controlling the release of different drugs by encapsulating them in organic-inorganic hybrids via sol-gel technique. The assembled organic-inorganic hybrids had diverse BET surface area, porosity, and high heat resistance. The synthesized organic-inorganic hybrids were based on zirconium(IV) propoxide, and tetraethyl orthosilicate as precursor of inorganic network, and chitosan or N-triethylchitosan as organic or biopolymer components. In these hybrid composites, drug and biopolymer were coated with a mesoporous inorganic material. FT-IR, FE-SEM, DSC, BET, XRD techniques, and Zeta potential analysis used for investigating the formation of metformin/chitosan@ZrO2 and sodium naproxen/N-triethylchitosan@SiO2 hybrid composites. Then for investigating the role of sol-gel process, the release of metformin and sodium naproxen in the prepared hybrid composites was investigated as model drugs. Compare to drug/biopolymer composite, incorporation of ZrO2 or SiO2 coating enhanced the drug entrapment appreciably, and naturally reduced the rate of drug release. For example, the metformin/chitosan composite without ZrO2 coating released the whole drug in less than10 h in pH 7.4 when the composite coated with ZrO2 released the entrapped drug after 25 h.
In this work and in continuation of our strategy for improving the performance of heterogeneous c... more In this work and in continuation of our strategy for improving the performance of heterogeneous catalysts, the SiO 2 @GO-OSO 3 H catalyst was applied as a very efficient solid acid catalyst for the Beckmann rearrangement. This catalyst effectively catalyzed the liquid-phase Beckmann rearrangement of cyclohexanone oxime to capro-lactam in high yield under very mild conditions. The improvement of GO-OSO 3 H catalyst in regard to its separation from reaction mixture is achieved by coating it with a mesoporous SiO 2 layer. The influence of the operating parameters on the performance of the catalyst namely solvent, temperature, amount of catalyst, and time was studied.
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Papers by marieh ghazaie
encapsulating them in organic-inorganic hybrids via sol-gel technique. The assembled
organic-inorganic hybrids had diverse BET surface area, porosity, and high heat resistance.
The synthesized organic-inorganic hybrids were based on zirconium(IV) propoxide, and
tetraethyl orthosilicate as precursor of inorganic network, and chitosan or N-triethylchitosan
as organic or biopolymer components. In these hybrid composites, drug and biopolymer were
coated with a mesoporous inorganic material. FT-IR, FE-SEM, DSC, BET, XRD techniques,
and Zeta potential analysis used for investigating the formation of metformin/chitosan@ZrO2
and sodium naproxen/N-triethylchitosan@SiO2 hybrid composites. Then for investigating the
role of sol-gel process, the release of metformin and sodium naproxen in the prepared hybrid
composites was investigated as model drugs. Compare to drug/biopolymer composite,
incorporation of ZrO2 or SiO2 coating enhanced the drug entrapment appreciably, and
naturally reduced the rate of drug release. For example, the metformin/chitosan composite
without ZrO2 coating released the whole drug in less than10 h in pH 7.4 when the composite
coated with ZrO2 released the entrapped drug after 25 h.
encapsulating them in organic-inorganic hybrids via sol-gel technique. The assembled
organic-inorganic hybrids had diverse BET surface area, porosity, and high heat resistance.
The synthesized organic-inorganic hybrids were based on zirconium(IV) propoxide, and
tetraethyl orthosilicate as precursor of inorganic network, and chitosan or N-triethylchitosan
as organic or biopolymer components. In these hybrid composites, drug and biopolymer were
coated with a mesoporous inorganic material. FT-IR, FE-SEM, DSC, BET, XRD techniques,
and Zeta potential analysis used for investigating the formation of metformin/chitosan@ZrO2
and sodium naproxen/N-triethylchitosan@SiO2 hybrid composites. Then for investigating the
role of sol-gel process, the release of metformin and sodium naproxen in the prepared hybrid
composites was investigated as model drugs. Compare to drug/biopolymer composite,
incorporation of ZrO2 or SiO2 coating enhanced the drug entrapment appreciably, and
naturally reduced the rate of drug release. For example, the metformin/chitosan composite
without ZrO2 coating released the whole drug in less than10 h in pH 7.4 when the composite
coated with ZrO2 released the entrapped drug after 25 h.