Background: During the COVID-19 pandemic, we have witnessed increased complaints from third parti... more Background: During the COVID-19 pandemic, we have witnessed increased complaints from third parties about violent conditions through social media. This study aimed to determine the prevalence of domestic violence (DV) against women following exposure to the COVID-19 pandemic and its relevance to some related factors. Materials and methods: This study was conducted from July 2020 to May 2021 on married women of Babol, Iran. Eligible women entered into the study in a multi-stage cluster random sampling method. Data collection tools included demographic and family data, questionnaire HITS (Hurt, Insult, Threaten and Scream). Relationships were estimated using the Univariate and multivariate regression models. Results: The mean age of 488 women and their spouses was 34.62 ± 9.14 and 38.74 ± 9.07, respectively. Of the total female participants, 37 (7.6%), 68 (13.9%), and 21 (4.3%) were victims of total violence, verbal abuse, and physical violence, respectively. Ninety-five women (19.5) had a history of coronavirus infection. Women who were satisfied with their income and husbands were university educated, their chances of DV were reduced by 72% (95% CI (0.09-0.85), OR = 0.28) and 67% (95% CI (0.11-0.92), OR = 0.33) respectively. Drug abuse by husbands increased the likelihood of DV by up to 4 times (OR = 4.00), and more contact with their husbands at home due to home quarantine was more than twice as likely to have DV (OR = 2.64). Conclusion: Since the level of domestic violence was lower than before the coronavirus pandemic, it seems that most Iranian women were more under the support of their husbands during the coronavirus pandemic to endure the fear and panic caused by the pandemic. Women whose husbands had a university education and sufficient income had less domestic violence.
Maboudi et al. This is an open access article distributed under the terms of the Creative Commons... more Maboudi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Introduction Overt and subclinical thyroid dysfunction may present as female sexual dysfunction (... more Introduction Overt and subclinical thyroid dysfunction may present as female sexual dysfunction (FSD), through their hormonal effect or due to their consecutive psychiatric disorders. Objective To evaluate effect of thyroid dysfunction on FSD in reproductive-aged married premenopausal women in Basrah- Iraq. Methods We received 673 reproductive aged women with different sexually-related complaints. There were 229 women who fulfill the criteria of FSD diagnosis for more than 6 months, with exclusion of any women with any condition, medication, or intervention which might disturb the sexual function. The 229 women were tested by a cascade of hormonal investigations, including: thyrotropin stimulating hormone (TSH), free thyroxine (FT4), total testosterone (TT) with sex hormone binding globulin (SHBG), calculated free testosterone (cFT), estradiol (E2), and prolactin (PRL). We had diagnosed 42 women with different thyroid dysfunction and considered them as (case group), versus 187 women...
International Journal of Environmental Research and Public Health, 2020
Background: Extracellular matrix metalloproteinases (MMPs) play a pivotal role in the damage to t... more Background: Extracellular matrix metalloproteinases (MMPs) play a pivotal role in the damage to the periodontal tissue in patients with periodontitis. Scaling and root planning (SRP) attempt to control the plaque amount and consequentially reduce the bacterial load. Non-surgical periodontal treatment could be integrated with drug therapy and physiotherapy procedures such as ozone therapy. The aim of this study was to evaluate in a cohort of patients with a diagnosis of periodontitis: (1) the efficacy of non-surgical periodontal therapy assisted by the use of ozonated olive oil-based mouthwash on salivary metalloproteinase (MMP-8) and (2) the reduction of periodontal indices. Methods: Ninety-six subjects with a diagnosis of periodontitis were enrolled in this study and randomly assigned to the study group (SRP + mouthwash) or control group (SRP). The study duration was 3 months. Data on MMP-8, plaque index (PI), bleeding on probing (BoP) and probing pocket depth (PPD) were recorded a...
A Cross-Over Trial Using Insulin Glargine and Neutral Protamine Hagedorn insulin for the Poorly... more A Cross-Over Trial Using Insulin Glargine and Neutral Protamine Hagedorn insulin for the Poorly Controlled Patients with Type 2 Diabetes Who Refused Multiple Daily Insulin Injections Background: Data in the literature describing the comparison between Neutral Protamine Insulin of Hagedorn (NPH) and glargine insulins are conflicting. While some studies revealed the superiority of Glargine, others had shown comparable results and even NPH superiority figures. We have many patients on NPH basal therapy in our clinical practice and another good number on Glargine. We did observe adverse effects in both groups, but local data and real numbers comparing both regimens are lacking. Objective To compare basal insulin regimen using NPH or Glargine in efficacy, hypoglycaemic events, and weight gain. Design and setting: A prospective interventional crossover study was conducted in Faiha Specialized Diabetes, Endocrine and Metabolism Center from 2018 through 2021, involving patients less than ...
Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale
More than 20 million people in the East African horn and the southern Arabian Peninsula chew khat... more More than 20 million people in the East African horn and the southern Arabian Peninsula chew khat (Catha edulis) on a daily basis. The glycemic effect of khat chewing, regardless of diabetes status, is still being debated. Using studies from countries where chewing khat is common, we attempted to discuss the potential glycemic effects of Catha edulis in humans and some animal models. This review included a thorough search in PubMed and the Cochrane Library using PRISMA guidelines, with words like (Khat) and (Qat) serving as query indicators for (diabetes) and (glucose), with no language or species restrictions. Khat is chewed for its stimulating and enjoyable properties. Despite a relatively small number of studies on khat’s glycemic effect, the debate continues. Many studies have linked the glycemic effect of khat leaves to their freshness and the duration of the stimulant effect. Although only in animal models, khat’s destructive effect on pancreatic -cells could cause some dysgly...
Background The relationship between diabetic retinopathy (DR) and nephropathy in type 1 diabetes ... more Background The relationship between diabetic retinopathy (DR) and nephropathy in type 1 diabetes mellitus (T1DM) is controversial. This study assessed the utility of the spot urinary albumin creatinine ratio (UACR) as a parameter for correlating diabetic nephropathy with DR in individuals with T1DM in Basrah. Methods The study was a cross-sectional observational study of 216 patients with T1DM (16–49 years old) with different DR types. We used demographic variables, different T1DM-related variables (onset and duration of T1DM, glycemic control, latency between T1DM and DR onset, age of onset of DR), and biochemical investigations, such as spot UACR, renal function tests, glycated hemoglobin (HbA1c), anti-glutamic acid decarboxylase-65 (anti-GAD-65) antibody, lipid profile, and thyrotropin. We used ordinal regression analysis to test for the possible primary covariates and adjusted the findings with an analysis of covariates (ANCOVA). Results The patient population showed a slight ma...
Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale
Flutamide is a non-steroidal anti-androgen drug effective in the management of prostatic carcinom... more Flutamide is a non-steroidal anti-androgen drug effective in the management of prostatic carcinoma. The drug appears to be well tolerated with mild gastrointestinal adverse events and gynecomastia. Flutamide-induced hepatotoxicity may range from minor elevation in liver enzymes to hepatic failure. Here, we tried to discuss the possibility of hepatotoxicity induced by flutamide as antiandrogen therapy in a patient with prostatic adenocarcinoma. Here we present a 75-year-old man who commenced flutamide as a postoperative anti-androgen for prostatic adenocarcinoma for two months. He had markedly elevated levels of liver enzymes due to acute liver failure and subsequent multi-organ failure. The patient died after the failure of the resuscitation measures. The temporal relationship between the flutamide initiation and the emergence of hepatotoxicity is not clear, with a possible latency of 12-16 weeks. Careful monitoring of liver function test during flutamide therapy is essential to pre...
Background: During the COVID-19 pandemic, we have witnessed increased complaints from third parti... more Background: During the COVID-19 pandemic, we have witnessed increased complaints from third parties about violent conditions through social media. This study aimed to determine the prevalence of domestic violence (DV) against women following exposure to the COVID-19 pandemic and its relevance to some related factors. Materials and methods: This study was conducted from July 2020 to May 2021 on married women of Babol, Iran. Eligible women entered into the study in a multi-stage cluster random sampling method. Data collection tools included demographic and family data, questionnaire HITS (Hurt, Insult, Threaten and Scream). Relationships were estimated using the Univariate and multivariate regression models. Results: The mean age of 488 women and their spouses was 34.62 ± 9.14 and 38.74 ± 9.07, respectively. Of the total female participants, 37 (7.6%), 68 (13.9%), and 21 (4.3%) were victims of total violence, verbal abuse, and physical violence, respectively. Ninety-five women (19.5) had a history of coronavirus infection. Women who were satisfied with their income and husbands were university educated, their chances of DV were reduced by 72% (95% CI (0.09-0.85), OR = 0.28) and 67% (95% CI (0.11-0.92), OR = 0.33) respectively. Drug abuse by husbands increased the likelihood of DV by up to 4 times (OR = 4.00), and more contact with their husbands at home due to home quarantine was more than twice as likely to have DV (OR = 2.64). Conclusion: Since the level of domestic violence was lower than before the coronavirus pandemic, it seems that most Iranian women were more under the support of their husbands during the coronavirus pandemic to endure the fear and panic caused by the pandemic. Women whose husbands had a university education and sufficient income had less domestic violence.
Maboudi et al. This is an open access article distributed under the terms of the Creative Commons... more Maboudi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Introduction Overt and subclinical thyroid dysfunction may present as female sexual dysfunction (... more Introduction Overt and subclinical thyroid dysfunction may present as female sexual dysfunction (FSD), through their hormonal effect or due to their consecutive psychiatric disorders. Objective To evaluate effect of thyroid dysfunction on FSD in reproductive-aged married premenopausal women in Basrah- Iraq. Methods We received 673 reproductive aged women with different sexually-related complaints. There were 229 women who fulfill the criteria of FSD diagnosis for more than 6 months, with exclusion of any women with any condition, medication, or intervention which might disturb the sexual function. The 229 women were tested by a cascade of hormonal investigations, including: thyrotropin stimulating hormone (TSH), free thyroxine (FT4), total testosterone (TT) with sex hormone binding globulin (SHBG), calculated free testosterone (cFT), estradiol (E2), and prolactin (PRL). We had diagnosed 42 women with different thyroid dysfunction and considered them as (case group), versus 187 women...
International Journal of Environmental Research and Public Health, 2020
Background: Extracellular matrix metalloproteinases (MMPs) play a pivotal role in the damage to t... more Background: Extracellular matrix metalloproteinases (MMPs) play a pivotal role in the damage to the periodontal tissue in patients with periodontitis. Scaling and root planning (SRP) attempt to control the plaque amount and consequentially reduce the bacterial load. Non-surgical periodontal treatment could be integrated with drug therapy and physiotherapy procedures such as ozone therapy. The aim of this study was to evaluate in a cohort of patients with a diagnosis of periodontitis: (1) the efficacy of non-surgical periodontal therapy assisted by the use of ozonated olive oil-based mouthwash on salivary metalloproteinase (MMP-8) and (2) the reduction of periodontal indices. Methods: Ninety-six subjects with a diagnosis of periodontitis were enrolled in this study and randomly assigned to the study group (SRP + mouthwash) or control group (SRP). The study duration was 3 months. Data on MMP-8, plaque index (PI), bleeding on probing (BoP) and probing pocket depth (PPD) were recorded a...
A Cross-Over Trial Using Insulin Glargine and Neutral Protamine Hagedorn insulin for the Poorly... more A Cross-Over Trial Using Insulin Glargine and Neutral Protamine Hagedorn insulin for the Poorly Controlled Patients with Type 2 Diabetes Who Refused Multiple Daily Insulin Injections Background: Data in the literature describing the comparison between Neutral Protamine Insulin of Hagedorn (NPH) and glargine insulins are conflicting. While some studies revealed the superiority of Glargine, others had shown comparable results and even NPH superiority figures. We have many patients on NPH basal therapy in our clinical practice and another good number on Glargine. We did observe adverse effects in both groups, but local data and real numbers comparing both regimens are lacking. Objective To compare basal insulin regimen using NPH or Glargine in efficacy, hypoglycaemic events, and weight gain. Design and setting: A prospective interventional crossover study was conducted in Faiha Specialized Diabetes, Endocrine and Metabolism Center from 2018 through 2021, involving patients less than ...
Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale
More than 20 million people in the East African horn and the southern Arabian Peninsula chew khat... more More than 20 million people in the East African horn and the southern Arabian Peninsula chew khat (Catha edulis) on a daily basis. The glycemic effect of khat chewing, regardless of diabetes status, is still being debated. Using studies from countries where chewing khat is common, we attempted to discuss the potential glycemic effects of Catha edulis in humans and some animal models. This review included a thorough search in PubMed and the Cochrane Library using PRISMA guidelines, with words like (Khat) and (Qat) serving as query indicators for (diabetes) and (glucose), with no language or species restrictions. Khat is chewed for its stimulating and enjoyable properties. Despite a relatively small number of studies on khat’s glycemic effect, the debate continues. Many studies have linked the glycemic effect of khat leaves to their freshness and the duration of the stimulant effect. Although only in animal models, khat’s destructive effect on pancreatic -cells could cause some dysgly...
Background The relationship between diabetic retinopathy (DR) and nephropathy in type 1 diabetes ... more Background The relationship between diabetic retinopathy (DR) and nephropathy in type 1 diabetes mellitus (T1DM) is controversial. This study assessed the utility of the spot urinary albumin creatinine ratio (UACR) as a parameter for correlating diabetic nephropathy with DR in individuals with T1DM in Basrah. Methods The study was a cross-sectional observational study of 216 patients with T1DM (16–49 years old) with different DR types. We used demographic variables, different T1DM-related variables (onset and duration of T1DM, glycemic control, latency between T1DM and DR onset, age of onset of DR), and biochemical investigations, such as spot UACR, renal function tests, glycated hemoglobin (HbA1c), anti-glutamic acid decarboxylase-65 (anti-GAD-65) antibody, lipid profile, and thyrotropin. We used ordinal regression analysis to test for the possible primary covariates and adjusted the findings with an analysis of covariates (ANCOVA). Results The patient population showed a slight ma...
Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale
Flutamide is a non-steroidal anti-androgen drug effective in the management of prostatic carcinom... more Flutamide is a non-steroidal anti-androgen drug effective in the management of prostatic carcinoma. The drug appears to be well tolerated with mild gastrointestinal adverse events and gynecomastia. Flutamide-induced hepatotoxicity may range from minor elevation in liver enzymes to hepatic failure. Here, we tried to discuss the possibility of hepatotoxicity induced by flutamide as antiandrogen therapy in a patient with prostatic adenocarcinoma. Here we present a 75-year-old man who commenced flutamide as a postoperative anti-androgen for prostatic adenocarcinoma for two months. He had markedly elevated levels of liver enzymes due to acute liver failure and subsequent multi-organ failure. The patient died after the failure of the resuscitation measures. The temporal relationship between the flutamide initiation and the emergence of hepatotoxicity is not clear, with a possible latency of 12-16 weeks. Careful monitoring of liver function test during flutamide therapy is essential to pre...
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