5.8S ribosomal RNA
From Infogalactic: the planetary knowledge core
5.8S ribosomal RNA | |
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Predicted secondary structure and sequence conservation of 5.8S ribosomal RNA | |
Identifiers | |
Symbol | 5_8S_rRNA |
Rfam | RF00002 |
Other data | |
RNA type | Gene; rRNA |
Domain(s) | Eukaryota; Archaea |
GO | 0003735 0005840 |
SO | 0000375 |
In molecular biology the 5.8S ribosomal RNA (5.8S rRNA) is a non-coding RNA component of the large subunit of the eukaryotic ribosome and so plays an important role in protein translation. It is transcribed by RNA polymerase I as part of the 45S precursor that also contains 18S and 28S rRNA. Its function is thought to be in ribosome translocation.[1] It is also known to form covalent linkage to the p53 tumour suppressor protein.[2]
5.8S rRNA can be used as a reference gene for miRNA detection.[3]
References
External links
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