ACAT2

Not to be confused with Acyl-CoA:cholesterol acyltransferase or Acetyl-CoA C-acyltransferase.

Acetyl-CoA acetyltransferase 2
250px PDB rendering based on 1wl4.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1WL4, 1WL5
Identifiers
Symbol	ACAT2
External IDs	OMIM: 100678 MGI: 109182 HomoloGene: 55855 IUPHAR: 2436 ChEMBL: 2240 GeneCards: ACAT2 Gene
EC number	2.3.1.9
Gene ontology Molecular function • acetyl-CoA C-acetyltransferase activity • protein binding Cellular component • nucleus • nucleoplasm • nucleolus • cytoplasm • extracellular exosome Biological process • lipid metabolic process Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	39	110460
Ensembl	ENSG00000120437	ENSMUSG00000023832
UniProt	Q9BWD1	Q8CAY6
RefSeq (mRNA)	NM_001303253	NM_009338
RefSeq (protein)	NP_001290182	NP_033364
Location (UCSC)	Chr 6: 159.76 – 159.78 Mb	Chr 17: 12.94 – 12.96 Mb
PubMed search	[1]	[2]

Acetyl-CoA acetyltransferase, cytosolic, also known as cytosolic acetoacetyl-CoA thiolase, is an enzyme that in humans is encoded by the ACAT2 (acetyl-Coenzyme A acetyltransferase 2) gene

Acetyl-Coenzyme A acetyltransferase 2 is an acetyl-CoA C-acetyltransferase enzyme.

Gene

This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.