BAPTA

BAPTA

Skeletal formula of BAPTA
Ball-and-stick model of the BAPTA molecule
Names
IUPAC name 1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid
Identifiers
CAS Number	85233-19-8 N
ChEBI	CHEBI:60888 Y
ChemSpider	94562 Y
Jmol 3D model	Interactive image
PubChem	104751
InChI InChI=1S/C22H24N2O10/c25-19(26)11-23(12-20(27)28)15-5-1-3-7-17(15)33-9-10-34-18-8-4-2-6-16(18)24(13-21(29)30)14-22(31)32/h1-8H,9-14H2,(H,25,26)(H,27,28)(H,29,30)(H,31,32) Y Key: FTEDXVNDVHYDQW-UHFFFAOYSA-N Y InChI=1/C22H24N2O10/c25-19(26)11-23(12-20(27)28)15-5-1-3-7-17(15)33-9-10-34-18-8-4-2-6-16(18)24(13-21(29)30)14-22(31)32/h1-8H,9-14H2,(H,25,26)(H,27,28)(H,29,30)(H,31,32) Key: FTEDXVNDVHYDQW-UHFFFAOYAD
SMILES O=C(O)CN(c2ccccc2OCCOc1ccccc1N(CC(=O)O)CC(=O)O)CC(=O)O
Properties
Chemical formula	C22H24N2O10
Molar mass	476.433
Density	1.494 g/cm3
Melting point	177 to 179 °C (351 to 354 °F; 450 to 452 K)
Vapor pressure	{{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

BAPTA (1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid) is a calcium-specific aminopolycarboxylic acid. The presence of four carboxylic acid functional groups makes possible the binding of two calcium ions. The extensive flexibility of the carboxylate ligands is critical to the coordination of calcium and other metal ions.

There is a range of reported values for the dissociation constant of BAPTA, though 0.2 µM appears consistently. The rate constant for calcium binding is 500 µM⁻¹ s⁻¹.

See also

• EDTA
• EGTA
• Fura-2