Cefminox

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Cefminox
Cefminox.svg
Systematic (IUPAC) name
(6R,7S)-7-(((((2S)-2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
Clinical data
AHFS/Drugs.com International Drug Names
Legal status
  • ℞ (Prescription only)
Routes of
administration
IM, IV
Identifiers
CAS Number 84305-41-9 YesY
ATC code J01DC12 (WHO)
PubChem CID: 71141
ChemSpider 64286 N
UNII PW08Y13465 YesY
KEGG D07642 YesY
ChEMBL CHEMBL1276342 N
Chemical data
Formula C16H21N7O7S3
Molecular mass 519.57 g/mol
  • O=C2N1/C(=C(\CS[C@@H]1[C@]2(OC)NC(=O)CSC[C@H](C(=O)O)N)CSc3nnnn3C)C(=O)O
  • InChI=1S/C16H21N7O7S3/c1-22-15(19-20-21-22)33-4-7-3-32-14-16(30-2,13(29)23(14)10(7)12(27)28)18-9(24)6-31-5-8(17)11(25)26/h8,14H,3-6,17H2,1-2H3,(H,18,24)(H,25,26)(H,27,28)/t8-,14-,16+/m1/s1 N
  • Key:JSDXOWVAHXDYCU-VXSYNFHWSA-N N
 NYesY (what is this?)  (verify)

Cefminox (INN) is a second-generation cephalosporin antibiotic.[1][2]

Spectrum

Cefminox is a broad-spectrum, bactericidal cephalosporin antibiotic. It is especially effective against Gram-negative and anaerobic bacteria. The following represents MIC data for a few medically significant microorganisms.

  • Clostridium difficile: 2 - 4 µg/ml
  • Escherichia coli: 0.125 - 16 µg/ml
  • Pseudomonas aeruginosa: 256 µg/ml

[3]

References


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