EPS8
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Epidermal growth factor receptor kinase substrate 8 is an enzyme that in humans is encoded by the EPS8 gene.[1][2]
Function
This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.[2]
Clinical significance
Mutations in EPS8 cause congenital deafness .Lua error in package.lua at line 80: module 'strict' not found.
Interactions
EPS8 has been shown to interact with:
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References
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<references />, or <references group="..." />Further reading
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