Fosfestrol

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Fosfestrol
Fosfestrol.svg
Systematic (IUPAC) name
[4-[4-(4-phosphonooxyphenyl)hex-3-en-3-yl]
phenoxy]phosphonic acid
Clinical data
Trade names Honvan
AHFS/Drugs.com International Drug Names
Legal status
  • ℞ (Prescription only)
Identifiers
CAS Number 13425-53-1 N
ATC code L02AA04 (WHO)
PubChem CID: 3032325
ChemSpider 2297327 YesY
UNII A0E0NMA80F YesY
KEGG D00946 YesY
ChEMBL CHEMBL1200598 N
Chemical data
Formula C18H22O8P2
Molecular mass 428.310 g/mol
  • O=P(Oc1ccc(cc1)\C(=C(\c2ccc(OP(=O)(O)O)cc2)CC)CC)(O)O
  • InChI=1S/C18H22O8P2/c1-3-17(13-5-9-15(10-6-13)25-27(19,20)21)18(4-2)14-7-11-16(12-8-14)26-28(22,23)24/h5-12H,3-4H2,1-2H3,(H2,19,20,21)(H2,22,23,24)/b18-17+ YesY
  • Key:NLORYLAYLIXTID-ISLYRVAYSA-N YesY
 NYesY (what is this?)  (verify)

Fosfestrol (INN, BAN, JAN) (brand names Honvan, Difostilben, Fosfostilben, Fostrolin, Stilbol, Stilphostrol, Vagestrol, among others), also known as diethylstilbestrol diphosphate (DESDP, DESP), is a synthetic, non-steroidal estrogen of the stilbestrol group that is used in the treatment of prostate cancer.[1][2] It is a prodrug of diethylstilbestrol.[3]

See also

References

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