GABA transporter

GABA transporters are neurotransmitter transporters including:

• • GABA transporter type 1 (GAT1; SLC6A1)
  • GABA transporter type 2 (GAT2; SLC6A13)
  • GABA transporter type 3 (GAT3; SLC6A11)
  • Betaine transporter (BGT1; SLC6A12)
  • Vesicular GABA transporter (VGAT)

GAT1 and GAT3 are the major GABA transporters in brain plasma membranes. GAT2 and BGT1 are also expressed in the brain, but at low levels and mostly in the meninges. GAT2 also transports taurine, while BGT1 transports betaine. These two transporters are predominantly expressed in the liver, but are also found in the kidneys and, as mentioned above, in the meninges.