L-687,384

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L-687,384
Systematic (IUPAC) name
200px
1'-benzylspiro[2,3-dihydro-1H-naphthalene-4,4'-piperidine]
Identifiers
CAS Number	95417-67-7^Y
ATC code	none
PubChem	CID: 125328
ChemSpider	111534^N
Chemical data
Formula	C₂₁H₂₅N
Molecular mass	291.429 g/mol
SMILES c3ccccc3CN2CCC1(CC2)CCCc4c1cccc4
InChI InChI=1S/C21H25N/c1-2-7-18(8-3-1)17-22-15-13-21(14-16-22)12-6-10-19-9-4-5-11-20(19)21/h1-5,7-9,11H,6,10,12-17H2^N Key:MLDCBJPLHBPJET-UHFFFAOYSA-N^N

^NY (what is this?) (verify)

L-687,384 is a sigma receptor agonist, selective for the σ₁ subtype,^[1] as well as an NMDA antagonist.^[2]

References

σ (1, 2)

Agonists	3-MeO-PCE 3-MeO-PCP 3-PPP 4-MeO-PCP 4-IBP 4-PPBP Afobazole Alazocine Amitriptyline Arketamine BD-1008 BD1031 BD1052 Berberine Buprenorphine Captodiame Citalopram Clorgiline Cocaine Cutamesine Cyclazocine DHEA DHEA-S Desipramine Dextrallorphan Dextromethorphan Dextrorphan Dimemorfan DMT DTG Escitalopram Fluoxetine Fluvoxamine Heroin Ibogaine Igmesine Imipramine JO-1784 Ketamine L-687,384 Lamotrigine Lu 28-179 MDMA Metaphit Methamphetamine Methoxetamine Methylphenidate Morphine Naluzotan Noscapine OPC-14523 Opipramol PB-28 PD-144,415 Pentazocine Pentoxyverine Phencyclidine PRE-084 Pregnenolone Pregnenolone sulfate Quetiapine RTI-55 SA-4503 Siramesine Tapentadol Tenocyclidine Tramadol UMB23 UMB82 Venlafaxine
Antagonists	AC927 AHD1 AZ66 BD1008 BD-1047 BD1060 BD1063 BD1067 BMY-14802 CM156 E-5842 Haloperidol Lamotrigine LR132 LR172 Memantine MIN-101 MS-377 NE-100 Panamesine PD-144418 Progesterone Rimcazole S1RA (E-52862) Sertraline SM-21 SR-31742A UMB100 UMB101 UMB103 UMB116 YZ-011 YZ-069 YZ-185
Unknown/unsorted	4C-T-2 5-MeO-DiPT 18-MC β-Endopsychosin Clocapramine DiPT DPT Gevotroline TMA; Allosteric modulators: SKF-83959

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