rpoE
The gene rpoE (RNA polymerase, extracytoplasmic E) encodes the sigma factor sigma-24 (σ24, sigma E, or RpoE), a protein in Escherichia coli[1] and other species of bacteria. Depending on the bacterial species, this gene may be referred to as sigE.[2]
RpoE appears to be necessary for the exocytoplasmic stress response. E. coli mutants without rpoE cannot grow at high temperatures (that is, above 42 degrees C)[3] and show growth defects at lower temperatures, though this may be due to compensatory mutations.[4] In some bacterial species, such as Clostridium botulinum, this sigma factor may be necessary for sporulation.[5]
The stress response regulation activities of RpoE are modulated by the Hfq protein in E. coli.[6]
References
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