Small nucleolar RNA SNORD110

Small Nucleolar RNA SNORD110
220px
Predicted secondary structure and sequence conservation of SNORD110
Identifiers
Symbol	SNORD110
Rfam	RF00610
Other data
RNA type	Gene; snRNA; snoRNA; C/D-box
Domain(s)	Eukaryota
GO	0006396 0005730
SO	0000593

Small Nucleolar RNA SNORD110 (also known as HBII-55) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.

HBII-55 belongs to the C/D box class of snoRNAs which contain the C (UGAUGA) and D (CUGA) box motifs. Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. HBII-55 is predicted to guide the 2'O-ribose methylation of 18S ribosomal RNA (rRNA) at residue U1288.

External links

• Page for Small Nucleolar RNA SNORD110 at Rfam
• Entry for SNORD110 at snoRNABase