Sphingomyelin deacylase
From Infogalactic: the planetary knowledge core
| Sphingomyelin deacylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.5.1.109 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Sphingomyelin deacylase (EC 3.5.1.109, SM deacylase, GcSM deacylase, glucosylceramide sphingomyelin deacylase, sphingomyelin glucosylceramide deacylase, SM glucosylceramide GCer deacylase, SM-GCer deacylase, SMGCer deacylase) is an enzyme with systematic name N-acyl-sphingosylphosphorylcholine amidohydrolase.[1][2][3] This enzyme catalyses the following chemical reaction
- (1) an N-acyl-sphingosylphosphorylcholine + H2O
a fatty acid + sphingosylphosphorylcholine;; - (2) a D-glucosyl-N-acylsphingosine + H2O a fatty acid + D-glucosyl-sphingosine
The enzyme is involved in the sphingolipid metabolism in the epidermis.
References
External links
- Sphingomyelin deacylase at the US National Library of Medicine Medical Subject Headings (MeSH)
